15533-09-2
15533-09-2
Chemical Structure
Compound C108
- CAS No.: 15533-09-2
- Formula:C15H14N2O3
- Molecular Weight:270.28
IUPAC Name: (E)-2-hydroxy-N'-(1-(2-hydroxyphenyl)ethylidene)benzohydrazide
InChIKey: LQGMBUGEAAGJKW-MHWRWJLKSA-N
SMILES: O=C(N/N=C(C1=CC=CC=C1O)\C)C2=CC=CC=C2O
Biological Activity: Compound C108 is a G3BP2 inhibitor. Compound C108 also targeted stress granule-associated proteins and Gtpase-activating protein (SH3 domain) binding protein 2. Compound C108 potently inhibits esophageal squamous cell carcinoma (ESCC) cell metastasis[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Compound C108 | 99.32% | Compound C108 is a G3BP2 inhibitor. Compound C108 also targeted stress granule-associated proteins and Gtpase-activating protein (SH3 domain) binding protein 2. Compound C108 potently inhibits esophageal squamous cell carcinoma (ESCC) cell metastasis. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.84
HY-160191LSD1-IN-30 -
Similarity Score 0.82
HY-103528RSCS (Standard) -
Similarity Score 0.76
HY-123579Androgen receptor ligand 4 -
Similarity Score 0.72
HY-114503NSAH -
Similarity Score 0.72
HY-114503A(E/Z)-NSAH -
Similarity Score 0.71
HY-112914mTOR inhibitor-1 -
Similarity Score 0.69
HY-W1542652,2′-Dihydroxychalcone -
Similarity Score 0.69
HY-135474KM91104 -
Similarity Score 0.68
HY-B1408RSalicylanilide (Standard) -
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References
- [1]. Gupta N, et al. Stress granule-associated protein G3BP2 regulates breast tumor initiation. Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):1033-1038. [Content Brief]
- [2]. Zheng Y, et al. G3BP2 regulated by the lncRNA LINC01554 facilitates esophageal squamous cell carcinoma metastasis through stabilizing HDGF transcript. Oncogene. 2022 Jan;41(4):515-526. [Content Brief]
