C/EBPα inducer 1
Based on 1 publication(s) in Google Scholar
C/EBPα inducer 1 (compound 78) is a potent inducer of C/EBPα and myeloid differentiation.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity : 99.82%
- CAS No.: 2374285-52-4
- 화학식: C20H12FN3O4
- 분자량:377.33
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보관:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Publications Citing Use of MedChemExpress (MCE) C/EBPα inducer 1
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Biological Activity
제품 설명
In Vitro
C/EBPα inducer 1 (compound 78, 3 μM) causes myeloid differentiation differentiation[1].
C/EBPα inducer 1 (compound 78) increases the expression of the neutrophil differentiation surface marker CD11b[1].
C/EBPα inducer 1 (compound 78) induces the expression of the neutrophil differentiation surface marker CD11b and upregulation of CEBPA and its downstream targets[1].
C/EBPα inducer 1 (compound 78) can upregulate G-CSF receptors, and render leukemic cells more sensitive to G-CSF stimulation[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2374285-52-4
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Appearance Solid
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분자량 377.33
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화학식 C20H12FN3O4
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Color Light yellow to yellow
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SMILES
O=C1N(C2=CC=CC=C2)C(/C=C/C3=CC=C([N+]([O-])=O)O3)=NC4=CC=C(F)C=C41
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
용액&용해도
In Vitro:
DMSO : 6.25 mg/mL (16.56 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (274 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6502 mL | 13.2510 mL | 26.5020 mL | 66.2550 mL |
| 5 mM | 0.5300 mL | 2.6502 mL | 5.3004 mL | 13.2510 mL | |
| 10 mM | 0.2650 mL | 1.3251 mL | 2.6502 mL | 6.6255 mL | |
| 15 mM | 0.1767 mL | 0.8834 mL | 1.7668 mL | 4.4170 mL |