C/EBPα inducer 1
Based on 1 Customer Validation
C/EBPα inducer 1 (compound 78) is a potent inducer of C/EBPα and myeloid differentiation.
For research use only. We do not sell to patients.
- Purity: 99.82%
- CAS No.: 2374285-52-4
- Formula: C20H12FN3O4
- Molecular Weight:377.33
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Biological Activity
C/EBPα inducer 1 (compound 78, 3 μM) causes myeloid differentiation differentiation[1].
C/EBPα inducer 1 (compound 78) increases the expression of the neutrophil differentiation surface marker CD11b[1].
C/EBPα inducer 1 (compound 78) induces the expression of the neutrophil differentiation surface marker CD11b and upregulation of CEBPA and its downstream targets[1].
C/EBPα inducer 1 (compound 78) can upregulate G-CSF receptors, and render leukemic cells more sensitive to G-CSF stimulation[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2374285-52-4
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Appearance Solid
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Molecular Weight 377.33
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Formula C20H12FN3O4
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Color Light yellow to yellow
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SMILES
O=C1N(C2=CC=CC=C2)C(/C=C/C3=CC=C([N+]([O-])=O)O3)=NC4=CC=C(F)C=C41
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 6.25 mg/mL (16.56 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6502 mL | 13.2510 mL | 26.5020 mL | 66.2550 mL |
| 5 mM | 0.5300 mL | 2.6502 mL | 5.3004 mL | 13.2510 mL | |
| 10 mM | 0.2650 mL | 1.3251 mL | 2.6502 mL | 6.6255 mL | |
| 15 mM | 0.1767 mL | 0.8834 mL | 1.7668 mL | 4.4170 mL |
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