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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
61 Results for "
Human dermal fibroblasts
" in MedChemExpress (MCE) Product Catalog:
Products (61)
61 Results for "Human dermal fibroblasts" in MCE Product Catalog:
Cat. No.: HY-W010736
CAS No.: 30334-71-5
Cat. No.: HY-P5237
CAS No.: 960608-16-6
Cat. No.: HY-P11112
CAS No.: 1609454-11-6
Research Areas:
Cat. No.: HY-164826
CAS No.: 30881-23-3
Target:
Interleukin Related Reactive Oxygen Species (ROS) MMP Pyroptosis Ferroptosis Notch Keap1-Nrf2 PINK1/Parkin Mitophagy Caspase Apoptosis
Research Areas:
Acetyl zingerone is an analog of Zingerone (HY-14621). Acetyl zingerone downregulates the expression of ROS metabolism-related genes, fibroblast senescence-related genes, keratinocyte differentiation-related genes, and IL-17A target genes. Acetyl zingerone inhibits the activities of MMP-1, MMP-3, and MMP-12, as well as the activation of NLRP3 inflammasome, pyroptosis (pyroptosis), ferroptosis (ferroptosis), cartilage destruction, and UVA-induced cyclobutane pyrimidine dimer formation. Acetyl zingerone upregulates the expression of collagen, proteoglycan, extracellular matrix glycoprotein, Notch pathway, and GPX4 gene, activates Nrf2 and HO-1, induces extracellular matrix synthesis and PINK1/Parkin-mediated mitophagy (mitophagy), and promotes chondrocyte survival. Acetyl zingerone alleviates the progression of osteoarthritis in mice . Acetyl zingerone can be used in research related to skin aging, inflammatory skin diseases, osteoarthritis, melanoma, and non-melanoma skin cancer .
Cat. No.: HY-N11072
CAS No.: 29836-40-6
Cat. No.: HY-P5261
CAS No.: 2673230-58-3
Synonyms: KP1
Target:
Research Areas:
Cat. No.: HY-W743654R
CAS No.: 470-38-2
Target:
Research Areas:
Capsorubin (Standard) is the analytical standard of Capsorubin. This product is intended for research and analytical applications. Capsorubin is a carotenoid found in peppers with multiple biological activities. Capsorubin (167 μM) inhibits lipid peroxidation induced by 2,2'-azobis(2,4-dimethylvaleronitrile) (AMVN) in vitro. Capsorubin (1 μM) reduces UVB-induced DNA strand breaks and apoptosis in human dermal fibroblasts. Capsorubin also inhibits Epstein-Barr virus early antigen (EBV-EA) activation induced by phorbol 12-myristate 13-acetate in Raji cells, a marker of tumorigenesis.
Cat. No.: HY-W097122
CAS No.: 170941-79-4
Target:
Research Areas:
Fmoc-Gly-Gly-Gly-OH is a self-assembling gelator tripeptide modified with 9-fluorenylmethoxycarbonyl (Fmoc). Fmoc-Gly-Gly-Gly-OH forms a secondary supramolecular network through non-covalent interactions in hybrid polymer hydrogel systems. Fmoc-Gly-Gly-Gly-OH contributes to the construction of double-network hydrogels. Fmoc-Gly-Gly-Gly-OH can be used in studies of tissue regeneration and biomedical delivery applications .
Cat. No.: HY-W745164
CAS No.: 340167-81-9
Target:
Cat. No.: HY-113365R
CAS No.: 601-57-0
Synonyms: 4-Cholesten-3-one (Standard)
Category:
Cat. No.: HY-W250160
CAS No.: 100403-24-5
Synonyms: Polydeoxyribonucleotide
Category:
Cat. No.: HY-D1463
CAS No.: 699018-10-5
Cat. No.: HY-W763546A
CAS No.: 26403-72-5
Cat. No.: HY-107425B
Purity: ≥99.0%
Target:
Research Areas:
cis-MZ 1 hydrate serves as a negative control for BRD4-targeted PROTAC MZ 1 (HY-107425). cis-MZ 1 hydrate can be used in colorectal cancer-related research .
Target:
Cat. No.: HY-W442049
CAS No.: 893412-73-2
Synonyms: HPR
Target:
Research Areas:
Hydroxypinacolone retinoate (HPR) is a direct-binding agonist of retinoic acid receptor (RAR). Hydroxypinacolone retinoate has low irritation and high stability; when formulated into nanoparticles, its transdermal efficiency is enhanced, allowing it to penetrate deep into the dermis and achieve sustained release. When used in combination with Retinyl propionate, hydroxypinacolone retinoate promotes fibroblast proliferation and upregulates the gene expression of type IV collagen, CRBP-I and RARB. Hydroxypinacolone retinoate can be used in research related to skin wrinkles and skin aging .
Cat. No.: HY-N12653
CAS No.: 99572-22-2
Synonyms: (-)-Exserohilone
Category:
Target:
Cat. No.: HY-147505
CAS No.: 2412142-93-7
Antitubercular agent-21 (Compound 15) is an antitubercular agent with an MIC of o.4 µg/mL against M. tuberculosis H37Rv. Antitubercular agent-21 exhibits lower activity against other microorganism such as bacteria gram-positive, gram-negative or fungi. Antitubercular agent-21 shows low cytotoxicity .
Cat. No.: HY-W010736R
CAS No.: 30334-71-5
Category:
Target:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
