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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
50 Results for "
NSC 20116
" in MedChemExpress (MCE) Product Catalog:
Products (50)
50 Results for "NSC 20116" in MCE Product Catalog:
Cat. No.: HY-168344
CAS No.: 1030781-08-8
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CACPD2011a-0001278239 is a β2AR mixed agonist that shows a wide range of high-affinity binding to both wild-type and T164I β2AR variants, with no cytotoxicity or mutagenicity, making it suitable for asthma research .
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Ameltolide (LY-201116; ADD 75073) is a novel anticonvulsant agent and can be used for epilepsy research .
Cat. No.: HY-50898C
CAS No.: 1187538-35-7
Synonyms: GW572016 tosylate; GW2016 tosylate
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Lapatinib (GW572016) tosylate is a potent, orally active inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively .
Cat. No.: HY-B1558
CAS No.: 90293-01-9
Synonyms: MCI-2016 free base
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Bifemelane is a nootropic compound. Bifemelan causes the first peak by stimulating release from intracellular Ca 2+ stores and the second by capacitive entry through store–operated Ca 2+ channels. Bifemelane will be provided as a pharmacological tool for basic studies on astrocytes .
Cat. No.: HY-76772A
Synonyms: (+)-SNI-2011; (+)-AF102B hydrochloride hemihydrate
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(+)-Cevimeline hydrochloride hemihydrate ((+)-SNI-2011), a potent muscarinic receptor agonist, is a candidate therapeutic drug for xerostomia in Sjogren's syndrome.
Cat. No.: HY-76772B
Synonyms: (-)-SNI-2011; (-)-AF102B hydrochloride hemihydrate
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(-)-Cevimeline hydrochloride hemihydrate ((-)-SNI-2011), a novel muscarinic receptor agonist, is a candidate therapeutic drug for xerostomia in Sjogren's syndrome.
Cat. No.: HY-164399A
CAS No.: 1202920-93-1
SST0116CL1 free base is a HSP90 inhibitor (IC50: 0.21 μM). SST0116CL1 free base binds to the ATP binding pocket of Hsp90, and interferes with Hsp90 chaperone function thus resulting in client protein (EGFR, CDK4 and AKT) degradation. SST0116CL1 free base induces degradation of Her2 in BT-474 cell (IC50: 0.2 μM). SST0116CL1 free base has antiproliferative activity and inhibits tumor growth. SST0116CL1 free base has antiproliferative activity and inhibits tumor growth. SST0116CL1 free base can be used for the study of leukemia, gastric and ovarian carcinoma .
Cat. No.: HY-50898R
CAS No.: 231277-92-2
Synonyms: GW572016 (Standard); GW2016 (Standard)
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Lapatinib (Standard) is the analytical standard of Lapatinib. This product is intended for research and analytical applications. Lapatinib (GW572016) is a potent, orally active inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively .
Cat. No.: HY-50898BR
CAS No.: 388082-78-8
Synonyms: GW572016 ditosylate monohydrate (Standard); GW2016 ditosylate monohydrate (Standard)
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Lapatinib (ditosylate monohydrate) (Standard) is the analytical standard of Lapatinib (ditosylate monohydrate). This product is intended for research and analytical applications. Lapatinib ditosylate monohydrate (GW572016 ditosylate monohydrate) is a potent, orally active inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively .
Cat. No.: HY-50898AR
CAS No.: 388082-77-7
Synonyms: GW572016 ditosylate (Standard); GW2016 ditosylate (Standard)
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Lapatinib (ditosylate) (Standard) is the analytical standard of Lapatinib (ditosylate). This product is intended for research and analytical applications. Lapatinib ditosylate (GW572016 ditosylate) is a potent, orally active inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively .
Cat. No.: HY-50898CS
CAS No.: 2749856-05-9
Synonyms: GW572016-d4 tosylate; GW2016-d4 tosylate
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Lapatinib-d4 (GW572016-d4) tosylate is deuterium labeled Lapatinib (tosylate). Lapatinib (GW572016) tosylate is a potent, orally active inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively .
Cat. No.: HY-50898S2
CAS No.: 2748212-14-6
Synonyms: GW572016-d5; GW2016-d5
Cat. No.: HY-164353
CAS No.: 2959475-51-3
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HX20111 is an ADC linker, and can be used for synthesis of ADCs .
Cat. No.: HY-P811641
Cat. No.: HY-P991528
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Cat. No.: HY-P88429A
Synonyms: FLJ20516
Cat. No.: HY-R00439A
hsa-miR-2116-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
