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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
34 Results for "
PS1
" in MedChemExpress (MCE) Product Catalog:
Products (34)
34 Results for "PS1" in MCE Product Catalog:
Cat. No.: HY-123761
CAS No.: 1374647-07-0
Target:
Research Areas:
L505-yne is an active site-directed γ-secretase inhibitor. L505-yne blocks photoaffinity labeling of PS1-NTF, PS1-CTF, and SPP by clickable GSI photoprobes, binds the γ-secretase complex and inhibits Aβ42 production. L458-BPyne can be used for the research of Alzheimer’s disease [1] .
Cat. No.: HY-RS11276
Target:
Research Areas:
PSEN1 Human Pre-designed siRNA Set A contains three designed siRNAs for PSEN1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-18157
CAS No.: 1100361-36-1
Target:
Research Areas:
SCH 900229 is a potent γ-secretase inhibitor with selective activity against PS1. The Aβ40 IC50 value of SCH 900229 is 1.3 nM, showing its excellent ability in reducing Aβ. SCH 900229 has shown good Aβ-lowering effects after oral administration in preclinical animal models. SCH 900229 has been advanced to human clinical trials for further development of compounds for the inhibition of Alzheimer's disease [1].
Cat. No.: HY-143675S
Cat. No.: HY-167592S
CAS No.: 2936622-56-7
Synonyms: 1-Heptadecanoyl-2-eicosatrienoyl-sn-glycero(d5)-3-phospho- L-serine sodium
Cat. No.: HY-182367
Target:
Research Areas:
TMN-OMe is a blood-brain barrier-permeable GPR39 agonist and a radiotracer for positron emission tomography (PET). TMN-OMe activates GPR39 by recruiting β-arrestin, exhibits highly selective binding ability in the mouse brain, and enables quantitative analysis of GPR39 at the in vivo level. TMN-OMe shows specific uptake in GPR39 knockout mice, Alzheimer's disease model (APP/PS1) mice, and blocking experiments. TMN-OMe facilitates in-depth exploration of changes in GPR39-related mechanisms in neurological diseases and is widely used in Alzheimer's disease research [1].
Cat. No.: HY-RS18076
Target:
Research Areas:
Psen1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Psen1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-164231
CAS No.: 132014-80-3
Synonyms: 1-Stearoyl-2-arachidonoyl-sn-glycero-3-phospho-L-serine; SAPS (18:0/20:4(5Z,8Z,11Z,14Z))
Target:
Research Areas:
18:0,20:4 PS (1-Stearoyl-2-arachidonoyl-sn-glycero-3-phospho-L-serine) is a phosphatidylserine component for RNA particle formulations. 18:0,20:4 PS can be used as RNA delivery vehicles [1].
Cat. No.: HY-164231A
CAS No.: 474967-15-2
Synonyms: 1-Stearoyl-2-arachidonoyl-sn-glycero-3-phospho-L-serine sodium; SAPS (18:0/20:4(5Z,8Z,11Z,14Z)) sodium
Target:
Research Areas:
18:0,20:4 PS (1-Stearoyl-2-arachidonoyl-sn-glycero-3-phospho-L-serine) sodium can be incorporated into RNA particles that act as RNA delivery vehicles for in vivo application, facilitating delivery of RNA to target tissues [1].
Cat. No.: HY-14371
CAS No.: 1055027-48-9
Target:
Research Areas:
LX2932 is an orally active LX2931 (HY-14370) analogue and S1P/S1PR signaling axis modulator. LX2932 yields a dose-dependent decrease in circulating lymphocyte numbers. LX2932 improves collagen-induced arthritis [1] .
Cat. No.: HY-P7453
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ACTB; Beta Actin; Actin Beta; PS1TP5BP1; Actin, Cytoplasmic 1; Β-Actin; PS1TP5-Binding Protein 1; BKRNS; Beta-Actin; BRWS1; Beta Cytoskeletal Actin; CSMH; HCG15971, Isoform CRA_b; DDS1; HCG15971, Isoform CRA_a; THC8; ACTB Protein; BNS; I(2)-Actin
Species:
Human
Source:
E. coli
Cat. No.: HY-P704538
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SRXN1; YKL086W; Prev. C20orf139; Sulfiredoxin 1 Homolog (S. Cerevisiae); SRX1; Chromosome 20 Open Reading Frame 139; Npn3; HBV PreS1-Transactivated Protein 5; Srx; CDNA FLJ25552 Fis, Clone JTH02127; Sulfiredoxin-1; PS1TP5; Sulphiredoxin; SRX; DJ850E9.2; S
Species:
Human
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
