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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
71 Results for "
Prostacyclin
" in MedChemExpress (MCE) Product Catalog:
Products (71)
71 Results for "Prostacyclin" in MCE Product Catalog:
Cat. No.: HY-A0096R
CAS No.: 78919-13-8
Synonyms: Ciloprost (Standard); ZK 36374 (Standard)
Cat. No.: HY-14870S3
CAS No.: 1265295-92-8
Synonyms: NS-304-d6; ACT-293987-d6
Cat. No.: HY-114671
CAS No.: 108945-35-3
Synonyms: CG-4203
Target:
Research Areas:
Taprostene (CG-4203) is a synthetic, chemically stable analogue of Prostacyclin (PGI2). Taprostene exhibits endothelium and myocardial protecting actions after acute myocardial ischemia and reperfusion in cats. Taprostene enhances cytoprotective actions, while minimizing unwanted hemodynamic effects .
Cat. No.: HY-A0096S
CAS No.: 1035094-10-0
Cat. No.: HY-14870R
CAS No.: 475086-01-2
Synonyms: NS-304 (Standard); ACT-293987 (Standard)
Research Areas:
Selexipag (Standard) is the analytical standard of Selexipag. This product is intended for research and analytical applications. Selexipag (NS-304) is an orally available and potent agonist for the Prostacyclin (PGI2) receptor (IP receptor).
Cat. No.: HY-173420
CAS No.: 155326-57-1
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Research Areas:
15-Keto Iloprost is a C-15 oxidized derivative of Iloprost (HY-A0096). Iloprost (ZK 36374) is a prostacyclin (PGI2) analogue, involves in embryo development and inflammation improvement, and inhibits tumor metastasis .
Cat. No.: HY-112079
CAS No.: 132684-62-9
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Research Areas:
NPC-15669 is a novel Mac-1 inhibitor. NPC-15669 reduces plasma levels of ET-1, TxB, prostacyclin, AT-III, and total protein S. NPC-15669 can be used in the research of myocardial infarction .
Cat. No.: HY-108912R
CAS No.: 221529-58-4
Synonyms: CAY10441 (Standard)
Research Areas:
RO1138452 (Standard) is the analytical standard of RO1138452. This product is intended for research and analytical applications. RO1138452 is a potent and selective IP (prostacyclin) receptor antagonist. RO1138452 displays high affinity for IP receptors. In human platelets, pKi is 9.3±0.1; in a recombinant IP receptor system, pKi is 8.7±0.06.
Cat. No.: HY-13569AR
CAS No.: 496807-11-5
Synonyms: TRK-100 (Standard); ML 1129 sodium (Standard)
Research Areas:
Beraprost (sodium) (Standard) is the analytical standard of Beraprost (sodium). This product is intended for research and analytical applications. Beraprost sodium, a prostacyclin analog, is a stable and orally active proagent of PGI2. Beraprost sodium is a potent vasodilator, has the potential for pulmonary arterial hypertension treatment through expanding renal vessels, improving microcirculation . Beraprost (sodium) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Cat. No.: HY-B1016R
CAS No.: 15421-84-8
Synonyms: AR-12008 (Standard)
Research Areas:
Trapidil (Standard) (AR-12008 (Standard)) is the analytical standard of Trapidil (HY-B1016R). This product is intended for research and analytical applications. Trapidil (AR-12008) is an orally active vasodilator and antiplatelet agent. Trapidil antagonizes platelet-derived growth factor (PDGF), inhibits phosphodiesterase, thromboxane A2 synthesis and pro-inflammatory cytokine production. Trapidil promotes prostacyclin biosynthesis, reduces lipid peroxidation, regulates nitric oxide metabolism, and inhibits cell proliferation and migration. Trapidil exerts tissue-protective effects, regulates bone turnover, and inhibits pyroptosis via the GPX3/Nrf2 pathway. Trapidil is applicable to research related to renal ischemia-reperfusion injury, chronic stable angina, restenosis, meningioma, diabetic cardiomyopathy and peripheral nerve crush injury.
Cat. No.: HY-A0126AR
CAS No.: 61849-14-7
Synonyms: Prostaglandin I2 sodium salt (Standard); Prostacyclin sodium salt (Standard); Flolan (Standard)
Research Areas:
Epoprostenol (sodium) (Standard) is the analytical standard of Epoprostenol (sodium). This product is intended for research and analytical applications. Epoprostenol sodium (Prostaglandin I2 (sodium salt)), the synthetic form of the natural prostaglandin derivative prostacyclin (prostaglandin I2), is registered worldwide for the treatment of Pulmonary arterial hypertension (PAH) . Epoprostenol sodium is used in pulmonary hypertension and transplantation as a potent inhibitor of platelet aggregation .
Cat. No.: HY-148670
CAS No.: 1201082-00-9
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Research Areas:
Pulmonary arterial hypertension agent-1 is a phenylphosphate-prodrug of a prostacyclin with activation by lung phosphatases to release prostacyclin. Pulmonary arterial hypertension agent-1 can be used for the research of pulmonary arterial hypertension .
Cat. No.: HY-123293
CAS No.: 72818-36-1
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UK 34787 is a selective thromboxane synthetase inhibitor with little or no activity against cyclooygenase or prostacyclin synthetase .
Cat. No.: HY-167091
CAS No.: 88430-50-6
Synonyms: (Rac)-TRK-100 free acid; (Rac)-ML 1229
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Research Areas:
(Rac)-Beraprost ((Rac)-ML 1229) is an orally active prostacyclin analog that inhibits the release of Ca 2+ from intracellular storage sites by binding to prostacyclin membrane receptors (Prostaglandin Receptor), leading to relaxation of smooth muscle cells and vasodilation. Beraprost has vasodilatory, antiplatelet, and cytoprotective effects, making it promising for research in the field of cardiovascular diseases, such as thromboangiitis obliterans and atherosclerosis .
Cat. No.: HY-127162
CAS No.: 69413-73-6
Synonyms: PGK1
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Research Areas:
Prostaglandin K1 (compound 46) is a structurally modified analog of prostacyclin (prostanoid) with an EC50 of 2800 nM for EP1 and a Ki of 2800 nM .
Cat. No.: HY-Z7721
CAS No.: 88475-69-8
Synonyms: (Rac)-TRK-100; (Rac)-ML 1129 sodium
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Research Areas:
(Rac)-Beraprost ((Rac)-ML 1129) sodium is a racemic isomer of Beraprost sodium (HY-13569A). Beraprost sodium is an orally active prostacyclin analog that inhibits the release of Ca 2+ from intracellular storage sites by binding to prostacyclin membrane receptors (Prostaglandin Receptor), leading to relaxation of smooth muscle cells and vasodilation. Beraprost sodium has vasodilatory, antiplatelet, and cytoprotective effects, making it promising for research in the field of cardiovascular diseases, such as thromboangiitis obliterans and atherosclerosis .
Cat. No.: HY-114587
CAS No.: 105284-21-7
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RS 93427-007 is an orally active prostacyclin stable mimetic agent. RS 93427-007 can be used for the research of cardiovascular disease, such as atherosclerosis .
Cat. No.: HY-105315
CAS No.: 171232-82-9
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Research Areas:
AFP-07 is a derivative of 7, 7-difluoroprostacyclic and is a highly potent and selective prostacyclin receptor IP receptor agonist with a Ki value of 0.561 nM .
Cat. No.: HY-120309
CAS No.: 136451-58-6
Target:
Research Areas:
BMY 42393 is an orally active prostacyclin agonist which suppresses monocyte-macrophage atherogenic activity and cytokine production. BMY 42393 can be used for atherosclerosis research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
