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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
71 Results for "
Prostacyclin
" in MedChemExpress (MCE) Product Catalog:
Products (71)
71 Results for "Prostacyclin" in MCE Product Catalog:
Cat. No.: HY-129293
CAS No.: 788799-13-3
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AFP-07 free acid is a derivative of 7, 7-difluoroprostacyclic and is a highly potent and selective prostacyclin receptor IP receptor agonist with a Ki value of 0.561 nM .
Cat. No.: HY-160993
CAS No.: 81845-44-5
Synonyms: 9β-Methylcarbacyclin
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Ciprostene is analog of prostacyclin (PGI2). Ciprostene inhibits adenosine diphosphate-induced platelet aggregation. Ciprostene can be used for research of peripheral vascular disease .
Cat. No.: HY-122499
CAS No.: 81703-55-1
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Ciprostene calcium is a prostacyclin analogue.Ciprostene calcium inhibits adenosine diphosphate-induced platelet aggregation. Ciprostene calcium can be used for research of peripheral vascular disease .
Cat. No.: HY-106699
CAS No.: 87440-45-7
Synonyms: CG 4203 sodium
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Taprostene sodium is a partial agonist at prostanoid prostacyclin (IP) receptors. Taprostene sodium interacts additively with Prostaglandin E2 (PGE2) (HY-101952), ONO-AE1-259 (selective EP2 agonist), and acetylcholine. Taprostene sodium exerts a significant cardioprotection .
Cat. No.: HY-142972
CAS No.: 115461-40-0
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19(S)-HETE is an arachidonic acid metabolite produced by cytochrome P450 enzymes. 19(S)-HETE is a full orthosteric agonist of the prostacyclin (IP) receptor with an EC50 value of 567 nM. 19(S)-HETE inhibits platelet activation and relaxation of vessels .
Cat. No.: HY-124124R
CAS No.: 114-33-0
Category:
Cat. No.: HY-106110
CAS No.: 101758-79-6
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OP-2507 is a prostacyclin analog. OP-2507 can increase brain glucose levels in mice, suppress the breakdown of energy metabolism under hypoxic conditions, and has a protective effect against changes in cyclic nucleotides in hypoxic brain tissue (specifically, an increase in cyclic AMP and a decrease in cyclic GMP). OP-2507 provides protective effects against brain hypoxia and edema .
Cat. No.: HY-137227
CAS No.: 71154-83-1
Synonyms: 15(R)-Pinanethromboxane A2
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15(R)-PTA2 (15(R)-Pinanethromboxane A2) is an antithrombotic agent that inhibits platelet aggregation. 15(R)-PTA2 inhibits stable prostaglandin endoperoxide analog-induced constriction of feline coronary arteries and stabilizes hepatic lysosomes. 15(R)-PTA2 also inhibits thromboxane synthase but has no effect on prostacyclin synthase .
Cat. No.: HY-173419
Synonyms: 5-cis-15(R)-Ciloprost; 5-cis-15(R)-ZK 36374
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5-cis-15(R)-Iloprost (5-cis-15(R)-Ciloprost) is the C-5 cis-isomer and 15(R)-epimer of Iloprost (HY-A0096). Iloprost is a prostacyclin (PGI2) analogue, involves in embryo development and inflammation improvement, and inhibits tumor metastasis. Iloprost can be used for peripheral vascular research .
Cat. No.: HY-W436495
CAS No.: 63983-53-9
Synonyms: 6,15-Diketo-13,14-dihydro-PGF1α
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6,15-Diketo-13,14-dihydro prostaglandin F1α (6,15-Diketo-13,14-dihydro-PGF1α) is a metabolite of prostacyclin (PGI2). 6,15-Diketo-13,14-dihydro prostaglandin F1α enhances intracellular cAMP and cholesterol metabolism in bovine arterial smooth muscle cells .
Cat. No.: HY-128932R
CAS No.: 75498-96-3
Synonyms: MT-141 (Standard)
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Cefminox (sodium) (MT-141) (Standard) is the analytical standard of Cefminox (sodium). This product is intended for research and analytical applications. Cefminox sodium is a semisynthetic cephamycin, which exhibits antibacterial activity. Cefminox sodium is a broad-spectrum, bactericidal cephalosporin antibiotic. Cefminox sodium also acts as a dual agonist of prostacyclin receptor (IP) and PPARγ. Cefminox sodium upregulates cAMP production and PTEN expression and inhibits Akt/mTOR signaling. Cefminox sodium also prevents pulmonary arterial hypertension in rat model .
Cat. No.: HY-B0428BR
CAS No.: 78712-43-3
Synonyms: OKY-046 hydrochloride (Standard)
Research Areas:
Cardiovascular Disease Neurological Disease Inflammation/Immunology
Ozagrel hydrochloride (Standard) is the analytical reference standard of Ozagrel hydrochloride (HY-B0428B). Ozagrel hydrochloride (OKY-046 hydrochloride) is a high selective and orally active thromboxane A2 (TXA2) synthase inhibitor with an IC50 of 11 nM. Ozagrel hydrochloride exerts anti-platelet aggregation, vasodilation and anti-inflammatory effects by inhibiting the production of TXA2 and increasing the production of prostacyclin (PGI2). Ozagrel hydrochloride can be used for the study of ischemic stroke, asthma and thromboembolic diseases .
Cat. No.: HY-108565R
CAS No.: 152575-66-1
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BMY 45778 (Standard) is the analytical standard of BMY 45778 (HY-108565). This product is intended for research and analytical applications. BMY 45778 is a non-prostanoid prostacyclin mimetic. BMY 45778 inhibits human (IC50 = 35 nM), rabbit (IC50: 136 nM) and rat (IC50 : 1.3 μM) platelet aggregation. BMY 45778 also activates adenylyl cyclase. BMY 45778 is a partial agonist at the prostacyclin receptor .
Cat. No.: HY-106790
CAS No.: 71097-83-1
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Nileprost is a prostacyclin analogue. Nileprost is a mixed type PGI2/PGE2 agonist. Nileprost can be studied in research on acute myocardial ischemia .
Cat. No.: HY-165434
CAS No.: 87269-59-8
Synonyms: EL 784
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Naxaprostene is a prostacyclin analogue. Naxaprostene was much more selective for IP receptors and tended towards partial agonism. Naxaprostene inhibits ADP-induced platelet aggregation. It has been shown to prevent rabbit carotid artery thrombosis.
Cat. No.: HY-173418
Synonyms: cPGI-biotin; Carbacyclin-biotin
Cat. No.: HY-106099
CAS No.: 95722-07-9
Synonyms: (R)-ZK 96480
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(R)-Cicaprost ((R)-ZK 96480) is an isomer of Cicaprost (HY-19583). Cicaprost is an orally active prostacyclin analog. Cicaprost inhibits platelet aggregation and release, and induces vasodilation. Cicaprost can be used in research related to breast cancer and pulmonary arterial hypertension .
Cat. No.: HY-187559
CAS No.: 99570-57-7
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U 68215 is an orally active benzindene prostacyclin (PGI2) analog. U 68215 exhibits potent anti-gastric ulcer and gastric emptying inhibitory effects without inducing side effects such as diarrhea. U 68215 can be used in studies on peptic ulcer treatment and gastrointestinal cytoprotection .
Cat. No.: HY-123200
CAS No.: 107534-95-2
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SC42619 free base is a selective platelet thrombin receptor (thrombin receptor) antagonist. SC42619 free base inhibits thrombin-induced platelet aggregation, secretion, calcium influx, and phosphatidic acid phosphorylation, as well as trypsin-induced platelet aggregation. SC42619 free base reduces the content of individual platelets. SC42619 free base inhibits prostacyclin (PGI2) synthesis in endothelial cells. SC42619 free base can be used for the research of hematological diseases .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
