174 Results for "

R-L3

" in MedChemExpress (MCE) Product Catalog:
Products (174)

174 Results for "R-L3" in MCE Product Catalog:

Cat. No.: HY-40354D
CAS No.: 1092578-46-5
Target:  

JAK

Research Areas:  

Inflammation/Immunology

(3R,4S)-Tofacitinib is an less active enantiomer of Tofacitinib. Tofacitinib inhibits JAK3 with IC50 of 1 nM.
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Cat. No.: HY-101046
CAS No.: 150323-78-7
Purity:  99.87%
Target:  

5-HT Receptor SARS-CoV

Research Areas:  

Neurological Disease

Quipazine dimaleate is a 5-HT agonist with a Ki value of 1.4 nM for displaces [3H]GR65630 from 5-HT3R in rat. Quipazine dimaleate shows antiviral activity against SARS-CoV-2 with an EC50 of 31.64 μM. Quipazine dimaleate behaves as a 5-HT3R antagonist in peripheral models. Quipazine dimaleate can be used for neurological disease research [3] .
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Cat. No.: HY-60263
CAS No.: 110013-18-8
Target:  

PROTAC Linkers

Research Areas:  

Others

(3R)-3-Pyrrolidinemethanol is a molecular building block and also a PROTAC linker, which can be used for the synthesis of PROTACs, such as NRX-0492 (HY-153357).
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Cat. No.: HY-169499
CAS No.: 1809064-89-8
Target:  

Acyltransferase

Research Areas:  

Metabolic Disease

(R)-2-(3-(2-Ethoxyphenoxy)piperidin-1-yl)pyrimidine-5-carboxylic Acid is an intermediate in the synthesis of the diacylglycerol acyltransferase 2 (DGAT-2) inhibitor Ervogastat.
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Cat. No.: HY-24170
CAS No.: 178445-89-1
Target:  

Drug Intermediate

Research Areas:  

Others

tert-Butyl (R)-2-(3-(3-(3,4-dimethoxyphenyl)-1-hydroxypropyl)phenoxy)acetate is a drug intermediate for synthesis of various active compounds.
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Cat. No.: HY-128720
CAS No.: 759-65-9
Purity:  ≥95.0%
Diethyl oxalpropionate is an intermediate for poly((R,S)-3,3-dimethylmalic acid) (PDMMLA) derivative synthesis. PDMMLA derivative can be used in synthesis of nanoparticles and study of warfarin encapsulation and controlled release .
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Cat. No.: HY-152581
Purity:  98.08%
Target:  

Cannabinoid Receptor

Research Areas:  

Inflammation/Immunology

CB2R antagonist 3 is a selective antagonist of cannabinoid type 2 receptor (CB2R). CB2R antagonist 3 has high affinity for human CB2R and specific selectivity for CB1R. CB2R antagonist 3 can be combined with CB65 (HY-110047), the activator of CB2R. CB2R antagonist 3 effectively up-regulates the expression of anti-inflammatory cytokines and down-regulates the expression of pro-inflammatory cytokines .
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Cat. No.: HY-60256
CAS No.: 72580-54-2
Research Areas:  

Others

(R)-Pyrrolidine-3-carboxylic acid is a proline derivative .
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Cat. No.: HY-W012864S1
CAS No.: 478506-49-9
(2S,3R)-2,3,4-Trihydroxybutanal- 13C-1 is the 13C labeled (2S,3R)-2,3,4-Trihydroxybutanal .
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Cat. No.: HY-W336015
CAS No.: 154804-54-3
Synonyms: (2R)-2,3-bis(heptadecanoyloxy)propyl hydrogen phosphate sodium
Research Areas:  

Metabolic Disease

1,2-Diheptadecanoyl-sn-glycero-3-phosphatidic acid (sodium) ((2R)-2,3-bis(heptadecanoyloxy)propyl hydrogen phosphate (sodium)) is an ester product.
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Cat. No.: HY-W140713
CAS No.: 76062-97-0
Target:  

Drug Derivative

Research Areas:  

Metabolic Disease

(R)-Methyl 3-hydroxytetradecanoate is an ester product.
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Cat. No.: HY-W008507
CAS No.: 453-17-8
(R)-2,3-Dihydroxypropanal, 80% is a biochemical assay reagent.
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Cat. No.: HY-W012864S2
CAS No.: 90913-09-0
(2S,3R)-2,3,4-Trihydroxybutanal- 13C-2 is the 13C labeled (2S,3R)-2,3,4-Trihydroxybutanal .
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Cat. No.: HY-W028142R
CAS No.: 4774-24-7
Quipazine is a 5-HT agonist with a Ki value of 1.4 nM for displaces [3H]GR65630 from 5-HT3R in rat. Quipazine shows antiviral activity against SARS-CoV-2 with an EC50 of 31.64 μM. Quipazine behaves as a 5-HT3R agonist in peripheral models. Quipazine can be used for neurological disease research [3] .
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Cat. No.: HY-161366
CAS No.: 3033806-03-7
Target:  

PI3K

Research Areas:  

Cancer

OMS14 is exhibits inhibitory activity for phosphoinositide 3-kinase γ (PI3Kγ) and PIK3CD/PIK3R1, which inhibits 19% PI3Kγ and 65% PIK3CD/PIK3R1 activity at 100 μM. OMS14 exhibits anticancer efficacy in various cancer cells .
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Cat. No.: HY-W1115222
CAS No.: 2952806-82-3
Research Areas:  

Cancer

(S)-Deoxy-thalidomide-(R)-pyrrolidine-3-carbaldehyde is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.
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Cat. No.: HY-108591R
CAS No.: 103342-82-1
Synonyms: R-L3 (Standard)
L-364,373 (Standard) is the analytical standard of L-364,373 (HY-108591). This product is intended for research and analytical applications. L-364,373 (R-L3) is a voltage-gated Kv7.1 (KCNQ1)/mink channels activator. L-364,373 activates Iks (slow delayed rectifier potassium current) and shortens action potential duration in guinea pig cardiac myocytes, and suppresses early afterdepolarizations in rabbit ventricular myocytes .
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Cat. No.: HY-W008507S3
CAS No.: 478529-64-5
(R)-2,3-Dihydroxypropanal-d is the deuterium labeled (R)-2,3-Dihydroxypropanal .
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Cat. No.: HY-W008507S
CAS No.: 478529-50-9
(R)-2,3-Dihydroxypropanal-3- 13C is the 13C labeled (R)-2,3-Dihydroxypropanal .
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