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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
45 Results for "
chiral compound
" in MedChemExpress (MCE) Product Catalog:
Products (45)
45 Results for "chiral compound" in MCE Product Catalog:
Cat. No.: HY-W007978A
CAS No.: 18531-95-8
Synonyms: S-(-)-2,2-Diamino-1,1-binaphthyl
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(S)-[1,1'-Binaphthalene]-2,2'-diamine (S-(-)-2,2-Diamino-1,1-binaphthyl) is a chiral diamine compound and chiral template for molecularly imprinted polymers applied as chiral stationary phases for HPLC separation of DABN racemates .
Cat. No.: HY-70027
CAS No.: 939981-37-0
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p53 and MDM2 protein-interaction inhibitor (chiral) (Compound 32) is an inhibitor of the interaction between p53 and MDM2. p53 and MDM2 protein-interaction inhibitor (chiral) has potential applications in cancer research .
Cat. No.: HY-W012885
CAS No.: 53562-86-0
Cat. No.: HY-W002530A
CAS No.: 163061-73-2
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(1R,2R)-1-Aminoindan-2-ol is the isomer of (1S,2R)-1-Aminoindan-2-ol (HY-W002530), and can be used as a biological material or organic compound for life science related research. (1R,2R)-1-Aminoindan-2-ol can be used as a starting material to prepare an indene-based chiral auxiliary that is used in the aldol reaction. (1R,2R)-1-Aminoindan-2-ol can be used as a starting material in the synthesis of oxazoline-alcohol ligands .
Cat. No.: HY-136592
CAS No.: 53949-53-4
Synonyms: 1-OH IBU
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1-Hydroxy-ibuprofen (1-OH IBU) is a hydroxylated metabolite of Ibuprofen (HY-78131), a chiral compound that exists in enantiomeric forms and is found in human urine after Ibuprofen administration. 1-Hydroxy-ibuprofen is used in inflammation research .
Cat. No.: HY-W295313
CAS No.: 20752-34-5
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(+)-Neoisomenthol is one of the isomers of (±)-Neoisomenthol. (±)-Neoisomenthol is a compound that belongs to the class of monoterpenes. (±)-Neoisomenthol is a volatile constituent of Mentha arvensis with a peppermint odor and taste. It is a chiral compound, existing as a racemic mixture of two enantiomers, (+)-neoisomenthol and (-)-neoisomenthol.
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N-Palmitoyl-L-aspartate (N-Palmitoyl aspartic acid) is a chiral compound with properties of the aggregates formed in aqueous solution .
Cat. No.: HY-W351380
CAS No.: 98674-83-0
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(-)-Anicyphos is a chiral catalyst with the activity of promoting the selectivity of specific reactions. (-)-Anicyphos is often used to synthesize complex chiral molecules in organic synthesis and shows excellent catalytic performance. By adjusting the reaction conditions, (-)-Anicyphos can significantly improve the stereospecificity of the product, providing an effective strategy for compound development.
Cat. No.: HY-167646
CAS No.: 1202707-24-1
Synonyms: 071031B
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Ammuxetine (071031B), a chiral compound, is a 5-HT and norepinephrine reuptake inhibitor (SSRI) with antidepressant activity and can be used in studies related to depression .
Cat. No.: HY-W178699
CAS No.: 491-02-1
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Cat. No.: HY-161249
CAS No.: 2173134-02-4
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Vanin-1-IN-4 (compound (S)-1) is vanin-1 inhibitor with a chiral methyl substituent, with profils as potent drug-candidate but exist as an amorphous solid .
Cat. No.: HY-W075744
CAS No.: 2049086-34-0
SK-J002-1n is a highly efficient catalyst with excellent cross-coupling reaction activity. SK-J002-1n is widely used in organic synthesis to construct complex molecular structures. The chiral properties of SK-J002-1n make it play an important role in the pharmaceutical industry and provide support for the synthesis of chiral compounds. SK-J002-1n can significantly improve the conversion efficiency and is an important component of transition metal catalysts.
Cat. No.: HY-117089R
CAS No.: 112281-77-3
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Tetraconazole (Standard) is the analytical standard of Tetraconazole. This product is intended for research and analytical applications. Tetraconazole, a chiral triazole fungicide, is widely used for the prevention of plant disease in wheat fields . Tetraconazole alters the methionine and ergosterol biosynthesis pathways in Saccharomyces yeasts promoting changes on volatile derived compounds .
Cat. No.: HY-W012874S
Synonyms: H-D-Thr-OH-d2
Cat. No.: HY-149727
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β2AR agonist 2(compound 8a) is a β2 -Adrenergic receptor (β2AR) agonist. β2AR agonist 2 is a saturated nitrogen ring compound containing 4- to 7-membered heterocycle. β2AR agonist 2 has a chiral structure (the -R form) by carrying carbon containing the essential hydroxyl, thereby enhancing cellular glucose uptake (GU) activity and significantly stimulating glucose uptake by skeletal muscle cells. β2AR agonist 2 can be used in the study of Type 2 Diabetes (T2D) .
Cat. No.: HY-16633
CAS No.: 1444006-79-4
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ELND 007 (Compound 34) is a metabolically stable γ-secretase inhibitor designed to selectively inhibit amyloid beta (Aβ) generation while minimizing Notch inhibition. Developed alongside ELND 006 (Compound 30), it underwent human clinical trials following a synthetic strategy emphasizing diversity and chirality. In preclinical studies, ELND 007 showed promising in vitro and in vivo characteristics, effectively reducing Aβ levels. Comparative studies with other γ-secretase inhibitors like Semagacestat, Begacestat, and Avagacestat highlighted its efficacy in lowering Aβ production, particularly demonstrated by reduced Aβ levels in the cerebrospinal fluid (CSF) of healthy human volunteers, suggesting potential therapeutic benefit for Alzheimer's disease .
Cat. No.: HY-156584
CAS No.: 1626364-18-8
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ODE-Bn-PMEG is an antiviral compound with strong inhibitory activity against HPV-11, -16, and -18. ODE-Bn-PMEG effectively reduced transient amplification of viral DNA in transfected cells at concentrations well below its cytotoxic levels. ODE-Bn-PMEG showed increased uptake in human foreskin fibroblasts and was able to be efficiently converted to the active antiviral metabolite PMEG diphosphate in vitro. The P-chiral enantiomer of ODE-Bn-PMEG showed comparable antiviral activity, indicating its potential application against multiple HPV types. ODE-Bn-PMEG is a promising candidate for local inhibition of HPV-16, HPV-18, and other high-risk types .
Cat. No.: HY-W479432
CAS No.: 84621-34-1
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(R)-Methyl 2-(3-oxocyclopentyl)acetate is a chiral organic compound that can be used as a drug intermediate .
Cat. No.: HY-Z16647
CAS No.: 64282-88-8
(-) -Neoisomenthol is one of the isomers of (±) -Neoisomenthol. (±) -Neoisomenthol is a compound that belongs to the class of monoterpenes. (±) -Neoisomenthol is a volatile constituent of Mentha arvensis with a peppermint odor and taste. It is a chiral compound, existing as a racemic mixture of two enantiomers, (+) -neoisomenthol and (-) -neoisomenthol.
Cat. No.: HY-L903
5,281 compounds
Fragment-based drug discovery (FBDD) is well suited for discovering both drug leads and chemical probes of protein function. 3-dimensionality (3D) diversity is pivotal because the molecular shape is one of the most important factors in molecular recognition by a biomolecule. There is a developing appreciation that 3D fragments could offer opportunities that are not provided by 2D fragments.
MCE 3D Diverse Fragment Library consists of 5,400 non-flat fragment-like molecules (average Fsp3 value 0.58). More than 4,700 fragment compounds contain at least one chiral center in the structure. The key concepts that underlie the library design were 3D shape, structural diversity, reactive functionality and fragment-like. This 3D Diverse Fragment Library brings higher fragment hit optimization and increases the likelihood to find innovative hits in FBDD.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
