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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
120 Results for "
PD-1/PD-L1 interaction
" in MedChemExpress (MCE) Product Catalog:
Products (120)
120 Results for "PD-1/PD-L1 interaction" in MCE Product Catalog:
Cat. No.: HY-P99345
CAS No.: 2022215-59-2
Synonyms: TSR-042; ANB-011; WBP-285
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Cat. No.: HY-P3139
CAS No.: 2426685-25-6
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PROTAC PD-1/PD-L1 degrader-1, a PD-1/PD-L1 PROTAC based on Cereblon E3 ligand, inhibits PD-1/PD-L1 interaction with an IC50 of 39.2 nM. PROTAC PD-1/PD-L1 degrader-1 significantly restores the immunity repressed in a co-culture model of Hep3B/OS-8/hPD-L1 and CD3 T cells. PROTAC PD-1/PD-L1 degrader-1 moderately reduces the protein levels of PD-L1 in a lysosome-dependent manner .
Cat. No.: HY-P99833
CAS No.: 2216751-26-5
Synonyms: CK-301; TG-1501
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PD-1/PD-L1-IN-14 (compound 17) is a bifunctional inhibitor of PD-1/PD-L1 interactions, with an IC50 of 27.8 nM. PD-1/PD-L1-IN-14 (compound 17) inhibits PD-1/PD-L1 interactions and promotes dimerization, internalization, and degradation of PD-L1 .
Cat. No.: HY-P99573
CAS No.: 2245725-04-4
Synonyms: MGD-013
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Cat. No.: HY-P99641
CAS No.: 1808081-43-7
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Cat. No.: HY-P99884
CAS No.: 2206792-50-7
Synonyms: PF-06801591
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Cat. No.: HY-P99544
CAS No.: 2417649-97-7
Synonyms: HBM-9167; KL-A167
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Cat. No.: HY-P99610
CAS No.: 2249882-54-8
Synonyms: BI-754091
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Cat. No.: HY-120402
CAS No.: 1675203-82-3
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BMS-200 is a potent PD-1/PD-L1 interaction inhibitor with an IC50 of 80 nM. BMS-200 can induce dimerization of PD-L1 .
Cat. No.: HY-P10950A
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Cat. No.: HY-P3143
CAS No.: 1629655-80-6
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BMSpep-57 is a potent and competitive macrocyclic peptide inhibitor of PD-1/PD-L1 interaction with an IC50 of 7.68 nM. BMSpep-57 binds to PD-L1 with Kds of 19 nM and 19.88 nM in MST and SPR assays, respectively. BMSpep-57 facilitates T cell function by in creasing IL-2 production in PBMCs .
Cat. No.: HY-P9972
CAS No.: 1935694-88-4
Synonyms: PDR001
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Cat. No.: HY-103048A
Purity: 99.34%
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Cat. No.: HY-P991739
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PD-1/PD-L1-IN-NP19 is a PD-1/PD-L1 inhibitor, with an IC50 of 12.5 nM for human PD-1/PD-L1 interaction. PD-1/PD-L1-IN-NP19 could activate the immune microenvironment in tumor, which may contribute to its antitumor effects .
Cat. No.: HY-P99723
CAS No.: 2168561-26-8
Synonyms: BCD-135
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Cat. No.: HY-P2478
CAS No.: 2815311-61-4
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Cat. No.: HY-P99633
CAS No.: 2342597-81-1
Synonyms: BGB-A333
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
