2. Immunology/Inflammation
  3. PD-1/PD-L1
  4. Cosibelimab

Cosibelimab  (Synonyms: CK-301; TG-1501)

Cat. No.: HY-P99833 Purity: 99.90%
COA

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Cosibelimab (CK-301; TG-1501) is a high-affinity, fully human PD-L1-blocking monoclonal antibody that binds PD-L1 and blocks its interaction with PD-1. Cosibelimab has a functional Fc domain and is capable of inducing ADCC and complement-dependent cytotoxicity (CDC)-mediated killing of PD-L1+ cell lines, including lymphoma cells.

For research use only. We do not sell to patients.

Cosibelimab Chemical Structure

Cosibelimab Chemical Structure

CAS No. : 2216751-26-5

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1 mg USD 300 In-stock
5 mg USD 780 In-stock
10 mg USD 1250 In-stock
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Description

Cosibelimab (CK-301; TG-1501) is a high-affinity, fully human PD-L1-blocking monoclonal antibody that binds PD-L1 and blocks its interaction with PD-1. Cosibelimab has a functional Fc domain and is capable of inducing ADCC and complement-dependent cytotoxicity (CDC)-mediated killing of PD-L1+ cell lines, including lymphoma cells[1].

Clinical Trial
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Cosibelimab]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation

Purity: 99.90%

COA (231 KB)

Handling Instructions (2659 KB)
References
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Cosibelimab Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cosibelimab2216751-26-5CK-301 TG-1501CK301CK 301TG1501TG 1501TG-1501PD-1/PD-L1PD-1/Programmed death-ligand 1PD-L1PD-1Fc domainlymphomaInhibitorinhibitorinhibit

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