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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
67 Results for "
RyR
" in MedChemExpress (MCE) Product Catalog:
Products (67)
67 Results for "RyR" in MCE Product Catalog:
Cat. No.: HY-W010950S
CAS No.: 127413-31-4
Cat. No.: HY-113273
CAS No.: 41708-91-2
Synonyms: Ap5A; P1,P5-Di(adenosine-5'-)pentaphosphate
Diadenosine pentaphosphate (Ap5A; P1,P5-Di(adenosine-5'-)pentaphosphate) is an endogenous generated diadenosine polyphosphate, possessing the dual identities of intracellular alarm signal and extracellular signaling molecule. Diadenosine pentaphosphate regulates calcium signaling in the nervous, cardiac and peripheral sensory systems by activating P2X1/P2X3/P2Y receptor and RyR2 channels (EC50 = 140 μM). Diadenosine pentaphosphate can be used in studies related to intracellular calcium release channels, cardiovascular diseases and nociception (pain) .
Cat. No.: HY-RS26453
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Ryr2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ryr2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS12369
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RYR2 Human Pre-designed siRNA Set A contains three designed siRNAs for RYR2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS12368
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RYR1 Human Pre-designed siRNA Set A contains three designed siRNAs for RYR1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-164631
CAS No.: 714906-29-3
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EL20 is a selective cardiac ryanodine receptor 2 (RyR2) inhibitor. EL20 inhibits diastolic Ca
2+ leakage from the sarcoplasmic reticulum, reducing delayed afterdepolarizations and triggered arrhythmias. EL20 is promising for research of cardiovascular diseases .
Cat. No.: HY-178437
CAS No.: 79067-75-7
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Bastadins-5 is a potent stabilizer for the open state of RYR1. Bastadins-5 enhances Ca 2+-induced Ca 2+ release. Bastadins-5 can be used in research on central nuclear disease and malignant hypothermia .
Cat. No.: HY-172152
CAS No.: 3024617-59-9
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MP-010 is a FKBP12 ligand that regulates cytosolic calcium by stabilizing RyR channel activity. MP-010 promotes functional improvement in SOD1 G93A amyotrophic lateral sclerosis (ALS) mice, as evidenced by improved motor coordination, increased integrity of neuromuscular junctions, and significantly enhanced survival of spinal motor neurons. MP-010 can be used for research in the field of neurological diseases .
Cat. No.: HY-P5424
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Cat. No.: HY-149779
CAS No.: 3012675-16-7
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RyR2 stabilizer-1 (compound 12a) is a potent RyR2 stabilizer and SERCA2a activator with EC50s of 2.7 μM for RyR2 and 383 nM for SERCA2. RyR2 stabilizer-1 inhibits Ca 2+ leakage from the SR RyR2 while promoting SERCA2 to pump Ca 2+ back to SR, which make RyR2 stabilizer-1 possible to prevent cardiac arrhythmias .
Cat. No.: HY-RS12370
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RYR3 Human Pre-designed siRNA Set A contains three designed siRNAs for RYR3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS19158
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Ryr3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ryr3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS19951
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Ryr2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ryr2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS19950
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Ryr1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ryr1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-146109
CAS No.: 2571579-14-9
RyRs activator 1 (compound 7f) is a potent activator of ryanodine receptors (RyRs). RyRs activator 1 at 0.5 mg/L displays 100% larvicidal activity. The larvicidal activity of RyRs activator 1 is 90% at 0.01 mg/L .
Cat. No.: HY-175506
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RyRs activator 6 (compound C3) is a ryanodine receptor (RyRs) activator that activates calcium release in insect neurons. RyRs activator 6 has insecticidal activity .
Cat. No.: HY-146110
CAS No.: 2408415-52-9
RyRs activator 2 (compound 7o) is a potent activator of ryanodine receptors (RyRs). RyRs activator 2 is 30% larvicidal activity, comparable to chlorantraniliprole (30%) and better than cyantraniliprole (10%) .
Cat. No.: HY-P5319
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Cat. No.: HY-156082
CAS No.: 2850333-35-4
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RyRs activator 3 (compound A4) is an effective insecticide against diamondback moths (M. separata) and diamondback moths (P. xylostella). The LC50 value of RyRs activator 3 against diamondback moth is 3.27 mg/L. RyRs activator 3 can bind to ryanodine receptor, increase cytoplasmic Ca2+ concentration, and produce biological toxicity .
Cat. No.: HY-P5114
CAS No.: 269745-22-4
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
