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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
87 Results for "
cellular systems
" in MedChemExpress (MCE) Product Catalog:
Products (87)
87 Results for "cellular systems" in MCE Product Catalog:
Cat. No.: HY-D1056B4
Synonyms: LPS, from bacterial (Salmonella typhosa)
It is recommended to prepare a solution with concentration ≥2 mg/mL. Vortex thoroughly for more than 10 minutes. Due to the adsorption characteristics of LPS, silanized container or low adsorption centrifuge tubes should be used for aliquoting and storage, and mix thoroughly before use.
Cat. No.: HY-125863C
CAS No.: 9001-40-5
Synonyms: G6PD, Bacillus sp.
Target:
Research Areas:
Glucose-6-phosphate dehydrogenase, Bacillus sp. (G6PD, Bacillus sp.) (EC 1.1.1.49) is an NADP-dependent antioxidant metabolic enzyme. Glucose-6-phosphate dehydrogenase, Bacillus sp. is induced by sublethal doses of Menadione (HY-B0332) and increasing concentrations of NaCl in Bacillus sp. F26. Glucose-6-phosphate dehydrogenase, Bacillus sp. catalyzes the oxidation of glucose-6-phosphate (G6P) to 6-phosphoglucono-δ-lactone, while reducing NADP + to NADPH, providing reducing power for the antioxidant defense system and cellular redox balance of Bacillus sp. F26. Glucose-6-phosphate dehydrogenase, Bacillus sp. is used in research related to diabetic complications .
Cat. No.: HY-P991381
Synonyms: PPMX-T003; TSP-A18
Research Areas:
Cat. No.: HY-150743A
Purity: 93.84%
Target:
Research Areas:
Biotin-labeled ODN 2395 (sodium), a C class oligodeoxynucleotide, is a TLR9 agonist. Biotin-labeled ODN 2395 (sodium) can be used to evaluate CpG ODN cellular uptake and localization using a biotin detection system and light microscopy.
Cat. No.: HY-146245A
Purity: 95.88%
Target:
Research Areas:
Biotin-labeled ODN 1826 (sodium), a class B CpG ODN (oligodeoxynucleotide), is a TLR9 agonist. Biotin-labeled ODN 1826 (sodium) can be used to evaluate CpG ODN cellular uptake and localization using a biotin detection system and light microscopy.
Cat. No.: HY-W247098
CAS No.: 217176-83-5
Synonyms: DHR 6G
Target:
Research Areas:
Dihydrorhodamine 6G (DHR 6G) is the reduced form of Rhodamine 6G, which is used as fluorescent mitochondrial dye. It is nonfluorescent, but it readily enters most of the cells and is oxidized by oxidative species or by cellular redox systems to the fluorescent rhodamine 6G that accumulates in mitochondrial membranes. Dihydrorhodamine 6G is useful for detecting reactive oxygen species (ROS) including superoxide .
Cat. No.: HY-D1056C1
Synonyms: LPS, from Salmonella enterica (Serotype enteritidis)
It is recommended to prepare a solution with concentration ≥2 mg/mL. Vortex thoroughly for more than 10 minutes. Due to the adsorption characteristics of LPS, silanized container or low adsorption centrifuge tubes should be used for aliquoting and storage, and mix thoroughly before use.
Cat. No.: HY-W040055R
CAS No.: 2009-64-5
Synonyms: D-(+)-Neopterin (Standard); D-erythro-Neopterin (Standard)
Category:
Cat. No.: HY-146244A
Purity: 97.23%
Target:
Research Areas:
Biotin-labeled agatolimod (sodium), a class B CpG ODN (oligodeoxynucleotide), is a TLR9 agonist. Biotin-labeled agatolimod (sodium) can be used to evaluate CpG ODN cellular uptake and localization using a biotin detection system and light microscopy.
Cat. No.: HY-113313R
CAS No.: 52-39-1
Target:
Research Areas:
AZ3391 is a potent inhibitor of PARP. AZ3391 is a quinoxaline derivative. PARP family of enzymes play an important role in a number of cellular processes, such as replication, recombination, chromatin remodeling, and DNA damage repair. AZ3391 has the potential for the research of diseases and conditions occurring in tissues in the central nervous system, such as the brain and spinal cord (extracted from patent WO2021260092A1, compound 23) .
Cat. No.: HY-D1056B2
Synonyms: LPS, from bacterial (Proteus mirabilis)
It is recommended to prepare a solution with concentration ≥2 mg/mL. Vortex thoroughly for more than 10 minutes. Due to the adsorption characteristics of LPS, silanized container or low adsorption centrifuge tubes should be used for aliquoting and storage, and mix thoroughly before use.
Cat. No.: HY-150741A
Target:
Research Areas:
Biotin-labeled ODN 2216 (sodium) is a human-specific TLR9 (toll-like receptor 9) ligand or agonist. Biotin-labeled ODN 2216 (sodium) can be used to evaluate CpG ODN cellular uptake and localization using a biotin detection system and light microscopy.
Cat. No.: HY-173599
Target:
Research Areas:
NUV-244 is a molecular glue degrader of PNPLA3 I148M. NUV-244 induces degradation via the ubiquitin-proteasome system involving the E3 ligase BFAR. NUV-244 promotes 26S proteasome-dependent degradation of PNPLA3 I148M. NUV-244 restores lipid droplet morphology and cellular fitness in hepatocytes expressing PNPLA3 I148M. NUV-244 can be used in the research of metabolic dysfunction-associated fatty liver disease .
Cat. No.: HY-185057
CAS No.: 41656-56-8
Synonyms: S-Lactylglutathione; (R)-S-Lactoylglutathione
Research Areas:
Cat. No.: HY-125863A
CAS No.: 9001-40-5
Synonyms: G6PD (Leuconostoc sp., recombinant)
Target:
Research Areas:
Glucose-6-phosphate dehydrogenase (Leuconostoc sp., recombinant) (G6PD (Leuconostoc sp., recombinant)) (EC 1.1.1.49) is an NADP-dependent antioxidant metabolic enzyme. Glucose-6-phosphate dehydrogenase (Leuconostoc sp., recombinant) can be induced by sublethal doses of Menadione (HY-B0332) and increasing concentrations of NaCl. Glucose-6-phosphate dehydrogenase (Leuconostoc sp., recombinant) catalyzes the oxidation of glucose-6-phosphate (G6P) to 6-phosphoglucono-δ-lactone, while reducing NADP + to NADPH, providing reducing power for the antioxidant defense system and cellular redox balance of bacteria. Glucose-6-phosphate dehydrogenase (Leuconostoc sp., recombinant) is used in research related to diabetic complications .
Cat. No.: HY-177728
CAS No.: 2413733-73-8
Target:
Research Areas:
MG degrader 3 is a molecular glue degrader that induces the degradation of multiple proteins including GSPT1, ZFP91 and CK1α via the ubiquitin-proteasome system, regulates protein stability and cellular signaling networks, and exhibits anti-proliferative activity against multiple myeloma cells. MG degrader 3 can be applied in the research of multiple myeloma .
Cat. No.: HY-P1803
CAS No.: 120253-69-2
Synonyms: PKCε; PRKCE ; Peptide Epsilon
Target:
Research Areas:
Cat. No.: HY-174086
CAS No.: 3071165-43-7
Research Areas:
PROTAC GPX4 degrader-4 is a potent GPX4 PROTAC degrader, with DC50 values of 1366.67 nM and 475.15 nM in T24 and RT4 cells, respectively. PROTAC GPX4 degrader-4 targets and degrades GPX4 protein via the ubiquitin-proteasome system, thereby inducing cellular ferroptosis. PROTAC GPX4 degrader-4 can be used for research on bladder cancer .
Cat. No.: HY-40118
CAS No.: 59936-29-7
Synonyms: Boc-L-proline methyl ester
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
