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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
65 Results for "
DPPE-PEG2000
" in MedChemExpress (MCE) Product Catalog:
Products (65)
65 Results for "DPPE-PEG2000" in MCE Product Catalog:
Cat. No.: HY-187785A
Synonyms: DPPE-PEG2000-Mal-Cys-SP94
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DPPE-PEG2000-SP94 (DPPE-PEG2000-Mal-Cys-SP94) is a functionalized PEGylated phospholipid conjugate composed of three modular components: 1,2-dipalmitoyl-sn-glycerol-3-phosphate ethanolamine (DPPE) as a lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 2000 Da, and an SP94 (HY-P11050A) peptide as a terminal targeting/functional ligand. DPPE-PEG2000-SP94 can be used in research on targeted drug delivery for hepatocellular carcinoma .
Cat. No.: HY-W1052492
DPPE-PEG2000-Mal is a conjugate composed of DPPE, PEG chains, and maleimide (Mal). The maleimide group in DPPE-PEG2000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
Cat. No.: HY-187750A
Synonyms: DPPE-PEG2000-Mal-Cys-RRRRRRHHHH
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DPPE-PEG2000-R6H4 (DPPE-PEG2000-Mal-Cys-RRRRRRHHHH) is a functionalized PEGylated phospholipid conjugate composed of three modular components: 1,2-dipalmitoyl-sn-glycerol-3-phosphate ethanolamine (DPPE) as a lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 2000 Da, and an R6H4 peptide as a terminal targeting/functional ligand. DPPE-PEG2000-R6H4 can be used in studies such as pH-responsive tumor-targeting drug delivery .
Cat. No.: HY-W1052523
DPPE-PEG2000-NH2 is a conjugate composed of DPPE, a PEG chain, and a terminal primary amino group (-NH2). The primary amino group in DPPE-PEG2000-NH2 can be covalently linked to functional groups such as carboxylic acids, NHS esters, and isocyanates for targeted modification of liposomes/nanoparticles.
Cat. No.: HY-187331A
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DPPE-PEG2000-TAT is a functionalized PEGylated lipid conjugate composed of three modular components: dipalmitoylphosphatidylethanolamine (DPPE) as the lipid anchoring group, PEG, and TAT peptide (YGRKKRRQRRR) (HY-P0281) as the terminal targeting/functional ligand. DPPE-PEG2000-TAT can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers to confer ligand-directed targeting capability against non-specific cell membrane penetration (heparan sulfate proteoglycans).
Cat. No.: HY-187741A
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DPPE-PEG2000-CSTSMLKAC is a functionalized PEGylated phospholipid conjugate composed of three modular components: 1,2-dipalmitoyl-sn-glycerol-3-phosphoethanolamine (DPPE) as a lipid anchoring group, a 2000 Da polyethylene glycol (PEG) spacer arm, and the CSTSMLKAC peptide as a terminal targeting/functional ligand. DPPE-PEG2000-CSTSMLKAC can be used in research on targeted drug delivery for ischemic heart disease .
Cat. No.: HY-187742A
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DPPE-PEG2000-CRPPR is a functionalized PEGylated phospholipid conjugate composed of three modular components: 1,2-dipalmitoyl-sn-glycerol-3-phosphate ethanolamine (DPPE) as a lipid anchoring group, a 2000 Da polyethylene glycol (PEG) spacer arm, and a CRPPR (HY-P10641A) peptide as a terminal targeting/functional ligand. DPPE-PEG2000-CRPPR can be used in studies of cardiac-targeted drug delivery .
Cat. No.: HY-187747A
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DPPE-PEG2000-VHPKQHRGGSKGC is a functionalized PEGylated phospholipid conjugate composed of three modular components: 1,2-dispalmitoyl-sn-glycerol-3-phosphate ethanolamine (DPPE) as a lipid anchoring group, a 2000 Da polyethylene glycol (PEG) spacer arm, and a VHPKQHRGGSKGC (HY-P11088A) peptide as a terminal targeting/functional ligand. DPPE-PEG2000-VHPKQHRGGSKGC can be used in research on targeted drug delivery in inflammation, tumor angiogenesis, and atherosclerosis .
Cat. No.: HY-184553A
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DPPE-PEG2000-WYRGRL is a functionalized PEGylated lipid conjugate composed of three modular components: dipalmitoylphosphatidylethanolamine (DPPE) as the lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 2000 Da, and WYRGRL peptide (HY-P10739)as the terminal targeting/functional ligand. DPPE-PEG2000-WYRGRL can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers to confer ligand-directed targeting capability against specific cell surface receptors in tumor and inflammatory microenvironments.
Cat. No.: HY-187782A
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DPPE-PEG2000-WLSEAGPVVTVRALRGTGSW is a functionalized PEGylated phospholipid conjugate composed of three modular components: 1,2-dispalmitoyl-sn-glycerol-3-phosphoethanolamine (DPPE) as a lipid anchoring group, a 2000 Da polyethylene glycol (PEG) spacer arm, and the WLSEAGPVVTVRALRGTGSW (HY-P3436) peptide as a terminal targeting/functional ligand. DPPE-PEG2000-WLSEAGPVVTVRALRGTGSW can be used in research on targeted drug delivery for cardiovascular diseases (such as myocardial infarction and heart failure) .
Cat. No.: HY-187775A
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DPPE-PEG2000-MG1 is a functionalized PEGylated phospholipid conjugate composed of three modular components: 1,2-dipalmitoyl-sn-glycerol-3-phosphate ethanolamine (DPPE) as a lipid anchoring group, a 2000 Da polyethylene glycol (PEG) spacer arm, and an MG1 (HY-P11315) peptide as a terminal targeting/functional ligand. DPPE-PEG2000-MG1 can be used in research on targeted drug delivery for neuroinflammation .
Cat. No.: HY-187776A
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DPPE-PEG2000-CTT2 is a functionalized PEGylated phospholipid conjugate composed of three modular components: 1,2-dispalmitoyl-sn-glycerol-3-phosphate ethanolamine (DPPE) as a lipid anchoring group, a 2000 Da polyethylene glycol (PEG) spacer arm, and the CTT2 peptide as a terminal targeting/functional ligand. DPPE-PEG2000-CTT2 can be used in research on targeted drug delivery to the tumor microenvironment .
Cat. No.: HY-184566A
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DPPE-PEG2000-iRGD is a functionalized PEGylated lipid conjugate composed of three modular components: dipalmitoylphosphatidylethanolamine (DPPE) as the lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 2000 Da, and iRGD peptide (HY-P0122) as the terminal targeting/functional ligand. DPPE-PEG2000-iRGD can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers to confer ligand-directed targeting capability against sequential binding to αv integrins on tumor vasculature → neuropilin-1 (NRP1) in tumor tissue.
Cat. No.: HY-187237A
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DPPE-PEG2000-cRGD is a functionalized PEGylated lipid conjugate composed of three modular components: dipalmitoylphosphatidylethanolamine (DPPE) as the lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 2000 Da, and cyclic RGD peptide (cyclo(Arg-Gly-Asp)) as the terminal targeting/functional ligand. DPPE-PEG2000-cRGD can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers to confer ligand-directed targeting capability against αvβ3/αvβ5 integrins on tumor vasculature and cancer cell surfaces.
Cat. No.: HY-184564A
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DPPE-PEG2000-T7 is a functionalized PEGylated lipid conjugate composed of three modular components: dipalmitoylphosphatidylethanolamine (DPPE) as the lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 2000 Da, and T7 peptide (HAIYPRH) as the terminal targeting/functional ligand. DPPE-PEG2000-T7 can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers to confer ligand-directed targeting capability against transferrin receptor (TfR/CD71) on the surface of cancer cells and brain endothelial cells.
Cat. No.: HY-187314A
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DPPE-PEG2000-RVG29 is a functionalized PEGylated lipid conjugate composed of three modular components: dipalmitoylphosphatidylethanolamine (DPPE) as the lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 2000 Da, and RVG29 peptide (YTIWMPENPRPGTPCDIFTNSRGKRASNG) (HY-P5623) as the terminal targeting/functional ligand. DPPE-PEG2000-RVG29 can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers to confer ligand-directed targeting capability against the nAChR α7 subunit on neurons and brain endothelial cells.
Cat. No.: HY-187321A
Synonyms: DPPE-PEG2000-Cys-SRNLIDC
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DPPE-PEG2000-LyP-1 is a functionalized PEGylated lipid conjugate composed of three modular components: dipalmitoylphosphatidylethanolamine (DPPE) as the lipid anchoring group, PEG, and LyP-1 peptide (CGNKRTRGC) (HY-P2526) as the terminal targeting/functional ligand. LyP-1 is a cyclic 9-amino acid peptide that specifically binds to p32/gC1qR protein, which is highly expressed on tumor-associated macrophages, lymphatic endothelial cells, and certain tumor cells. DPPE-PEG2000-LyP-1 can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers to confer ligand-directed targeting capability against p32/gC1qR protein on the surface of lymphatic vessels, tumor-associated macrophages, and tumor cells.
Cat. No.: HY-187313A
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DPPE-PEG2000-GE11 is a functionalized PEGylated lipid conjugate composed of three modular components: dipalmitoylphosphatidylethanolamine (DPPE) as the lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 2000 Da, and GE11 peptide (YHWYGYTPQNVI) (HY-P10128) as the terminal targeting/functional ligand. DPPE-PEG2000-GE11 can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers to confer ligand-directed targeting capability against EGFR (HER1) on the surface of various epithelial tumor cells (lung cancer, breast cancer, colorectal cancer, head and neck cancer).
Cat. No.: HY-182833A
CAS No.: 355150-30-0
DPPE-PEG2000-NHS is a conjugate composed of DPPE, PEG chains, and terminal active esters (NHS). The NHS ester in DMPE-PEG2000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.
Cat. No.: HY-P12133
CAS No.: 3080063-21-1
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Tapimtrutide is a gastric inhibitory polypeptide (GIP) and glucagon-like peptide 1 (GLP-1) receptor agonist. Tapimtrutide can be used for the research of diabetes .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
