189 Results for "

DR

" in MedChemExpress (MCE) Product Catalog:
Products (189)

189 Results for "DR" in MCE Product Catalog:

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Cat. No.: HY-170908
CAS No.: 19622-05-0
Target:  

5-HT Receptor

Research Areas:  

Neurological Disease

Pellotine is an alkaloid that can be isolated from Lophophora. Pellotine is the inverse agonist for 5-HT7 receptor with an EC50 of 291 nM. Pellotine exhibits good affinity to 5-HT1DR and 5-HT6R with Ki of 117 nM and 170 nM. Pellotine reduces intracellular cAMP levels, thereby reducing neuronal excitability and neurotransmitter release .
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Cat. No.: HY-P2507
CAS No.: 508230-31-7
Target:  

Inhibitory Antibodies

Research Areas:  

Cancer

NY-ESO-1 (87-111) is a pan-MHC class II-restricted peptide sequence. NY-ESO-1 (87-111) binds to multiple HLA-DR and HLA-DP4 molecules, and stimulates Th1-type and Th-2/Th0-type CD4 + T cells when presented in the context of HLA-DR and HLA-DP4 molecules .
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Cat. No.: HY-D0396
CAS No.: 6227-02-7
Synonyms: DR16
C.I. Direct red 16 is a good dyeing agent for cotton fabrics.
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Cat. No.: HY-P1901
CAS No.: 872036-64-1
Target:  

Insulin Receptor

Research Areas:  

Metabolic Disease

Insulin alpha-chain (1-13) is a human leucocyte antigen (HLA)-DR4-restricted epitope comprising the first 13 amino acids of the insulin A-chain .
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Cat. No.: HY-12520AR
CAS No.: 62717-42-4
Synonyms: (±)-SKF-38393 hyDRochloride (Standard); SKF-38393A (Standard)
SKF 38393 (hydrochloride) (Standard) is the analytical standard of SKF 38393 (hydrochloride). This product is intended for research and analytical applications. SKF 38393 hydrochloride is a selective agonist of the dopamine D1 receptor (D1DR) with an IC50 of 110 nM .
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Cat. No.: HY-172940
CAS No.: 2761081-30-3
Target:  

Apoptosis

Research Areas:  

Cancer

TBP-134 induce apoptosis primarily through DR5 and causes G2/M phase arrest. TBP-134 can be used in the research for pancreatic tumor .
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Cat. No.: HY-N1582
CAS No.: 33429-83-3
Synonyms: 3,4′-Dimethylquercetin
Quercetin 3,4′-dimethyl ether (3,4′-Dimethylquercetin) is a dimethoxyflavone can be isolated from Combretum quadrangulare. Quercetin 3,4′-dimethyl ether overcomes TRAIL resistance by enhancing DR5 expression and has anti-tumor activity .
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Cat. No.: HY-D3141
DR probe is a "dual-key-and-lock" fluorescent probe designed based on the Resorufin (HY-123533) scaffold (Ex/Em = 647 nm/663-738 nm). DR probe can be sequentially activated by hydrogen peroxide to form the intermediate SR, which acts as a tyrosinase substrate to trigger a fluorescence turn-on signal. DR probe can distinguish normal melanocytes from melanoma cells. DR probe supports cell imaging and can be applied to mouse melanoma models to achieve melanoma diagnosis with higher accuracy and lower false-positive rates. DR probe is applicable to relevant research on melanoma .
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Cat. No.: HY-P992225

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

Anti-DR3 Antibody is a monoclonal antibody that targets DR3. Anti-DR3 Antibody can be used in ELISA, FACS, and functional assays. For isotype controls of Anti-DR3 Antibody, please refer to Human IgG4 (S228P) kappa, Isotype Control (HY-P99003).
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Cat. No.: HY-187538
Research Areas:  

Neurological Disease

DR/5-HT7AR Ligand-1 is a ligand with a Ki value of 1.24 nM against human D2R, 5.78 nM against human D3R, 0.67 nM against human 5-HT1AR, and 19.9 nM against human 5-HT7AR. DR/5-HT7AR Ligand-1 can be used for the research of schizophrenia .
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Cat. No.: HY-RS17102
Research Areas:  

Others

Dr1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Dr1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS23546
Research Areas:  

Others

Dr1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Dr1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P11902
Research Areas:  

Cancer

IRS1 is an integrin-targeted, ROS-responsive self-assembling peptide prodrug molecule with selective anti-cancer activity against integrin-overexpressing tumor cells. IRS1 contains an RGD motif for integrin binding, can covalently bind to DR4/DR5, and promotes DR4/DR5 aggregation. After oxidation by ROS, IRS1 undergoes a morphological transition from nanoparticles to nanofibers, exposes the pharmacophore of Chlorambucil (HY-13593), disrupts cell membrane integrity, activates the extrinsic apoptosis pathway, and can penetrate and inhibit the three-dimensional uveal melanoma spheroid model. IRS1 can be used for the research of uveal melanoma .
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Cat. No.: HY-P8F045A
Synonyms: HLA-DR,HLA-DR-FITC,L243

Host:  

Mouse

Application:  

FC

Reactivity:  

Human

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Cat. No.: HY-P8F045C
Synonyms: HLA-DR,HLA-DR-PE,L243

Host:  

Mouse

Application:  

FC

Reactivity:  

Human

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Cat. No.: HY-P8F045F
Synonyms: HLA-DR,HLA-DR-PerCP,L243

Host:  

Mouse

Application:  

FC

Reactivity:  

Human

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Cat. No.: HY-P8F045I
Synonyms: HLA-DR,HLA-DR-APC,L243

Host:  

Mouse

Application:  

FC

Reactivity:  

Human

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Cat. No.: HY-P8F045B
Synonyms: HLA-DR,HLA-DR-AF488,L243

Host:  

Mouse

Application:  

FC

Reactivity:  

Human

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Cat. No.: HY-P8F045H
Synonyms: HLA-DR,HLA-DR-AF647,L243

Host:  

Mouse

Application:  

FC

Reactivity:  

Human

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Cat. No.: HY-P8F045K
Synonyms: HLA-DR,HLA-DR-AF700,L243

Host:  

Mouse

Application:  

FC

Reactivity:  

Human

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