Quercetin 3,4′-dimethyl ether
Based on 1 publication(s) in Google Scholar
Quercetin 3,4′-dimethyl ether (3,4′-Dimethylquercetin) is a dimethoxyflavone can be isolated from Combretum quadrangulare. Quercetin 3,4′-dimethyl ether overcomes TRAIL resistance by enhancing DR5 expression and has anti-tumor activity.
For research use only. We do not sell to patients.
- CAS No.: 33429-83-3
- Formula: C17H14O7
- Molecular Weight:330.29
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Publications Citing Use of MedChemExpress (MCE) Quercetin 3,4′-dimethyl ether
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| BV-2 | IC50 |
11.1 μM
Compound: 102
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Anti-inflammatory activity in mouse BV-2 cells assessed as inhibition of LPS-induced NO production preincubated with compound for 1 hrs followed by LPS stimulation and measured after 24 hrs by Griess reagent based assay
Anti-inflammatory activity in mouse BV-2 cells assessed as inhibition of LPS-induced NO production preincubated with compound for 1 hrs followed by LPS stimulation and measured after 24 hrs by Griess reagent based assay
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[PMID: 37683361] |
| KB | ED50 |
2 μg/mL
Compound: NSC-106970
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Cytotoxicity against human KB cells
Cytotoxicity against human KB cells
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[PMID: 469554] |
Chemical Information
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CAS No. 33429-83-3
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Molecular Weight 330.29
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Formula C17H14O7
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SMILES
O=C1C(OC)=C(C2=CC=C(OC)C(O)=C2)OC3=CC(O)=CC(O)=C13
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Synonyms
3,4′-Dimethylquercetin
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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Biochem Biophys Res Commun
Structure of quercetin 3,4'-dimethyl ether in complex with tubulin provides a rationale for drug design. [Abstract]2025 Sep 1:777:152245. PMID: 40578283
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Quercetin 3,4′-dimethyl ether Related Classifications
HY-N1582 Related Classifications
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