577 Results for "

IG

" in MedChemExpress (MCE) Product Catalog:
Products (577)

577 Results for "IG" in MCE Product Catalog:

Cat. No.: HY-P991208
Synonyms: human Flt3L; hFlt3L

Research Areas:  

Inflammation/Immunology

Flt-3L-Ig (hum/hum) (hFlt3L) is a Flt3 ligand. Flt-3L-Ig (hum/hum) enhances the release of inflammatory cytokines from myeloid cells and dendritic cells in BRGSF-CBC mice induced by OKT3. Flt-3L-Ig (hum/hum) increases the release of IL-2, CCL2 and CXCL10 in an OKT3-dependent manner. Flt-3L-Ig (hum/hum) can be used in studies related to cytokine release syndrome. Flt-3L-Ig (hum/hum) can be used in studies related to psoriasis-like skin inflammation .
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Cat. No.: HY-P990079
CAS No.: 2725062-35-9
Synonyms: BMS-986207; ONO-4686

Target:  

CD28

Research Areas:  

Inflammation/Immunology

Renvistobart is an immunoglobulin G1-κ, anti-[Homo sapiens TIGIT (T cell immunoreceptor with Ig domain and ITIM, VSIG9, VSTM3)] Homo sapiens monoclonal antibody .
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Cat. No.: HY-P990163

Research Areas:  

Inflammation/Immunology

Anti-Mouse Siglec-H Antibody (440c) is a rat-derived IgG2b type antibody inhibitor, targeting to mouse Siglec-H. Anti-Mouse Siglec-H Antibody (440c) recognizes sialic acid-binding immunoglobulin (Ig)-like lectin family (Siglec-H) selectively expressing on plasmacytoid DCs and interferon–producing cells. Anti-Mouse Siglec-H Antibody (440c) can be used for the researches of inflammation and immunology, such as colitis .
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Cat. No.: HY-P990030
CAS No.: 2581724-89-0
Synonyms: AB-308
Ralzapastotug (AB-308) is an anti-TIGIT (T cell immunoreceptor with Ig and ITIM domains) IgG1 monoclonal antibody .
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Cat. No.: HY-N6008
CAS No.: 41679-97-4
7-O-Methyl morroniside is an iridoid glycoside (IG) extracted from Cornus officinalis fructus, used in many traditional Chinese medicines .
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Cat. No.: HY-P990031
CAS No.: 2649362-29-6
Synonyms: M-6223
Dargistotug (M-6223) is a fully human IgG1 monoclonal antibody targeting TIGIT (T cell immune receptor with Ig domain and ITIM). TIGIT is an inhibitory immune checkpoint that promotes NK cell depletion and reduces the secretion of cytokines by binding to CD155 and other antibodies. It can also directly or indirectly inhibit effector T cells and upregulate Tregs cells, thereby exerting immunosuppression. Function .
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Cat. No.: HY-P99963
CAS No.: 2387417-06-1
Synonyms: HS636

Target:  

PD-1/PD-L1

Research Areas:  

Cancer

Sudubrilimab (HS636) is an Ig G1-kappa monoclonal antibody against PDL1. Sudubrilimab is fused at the C terminus of the heavy chain to a TGF-β1 receptor Ⅱ ectodomain (TGFBR2-ECD), and which can sequester the PD-1/PD-L1 pathway and TGF-β bioactivity in the immunosuppressive tumor microenvironment .
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Cat. No.: HY-162776
Research Areas:  

Infection

Succinate dehydrogenase-IN-3 (Ig) is an inhibitor of Succinate dehydrogenase (SDH). Succinate dehydrogenase-IN-3 has antifungal activity .
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Cat. No.: HY-169930
CAS No.: 1613196-91-0
Target:  

ATM/ATR

Research Areas:  

Cancer

ATR kinase-IN-2 (Compound I-G-27) is a ATR protein kinase inhibitor with the Ki of 0.01 ~ 1 μΜ and can be used for study of cancer .
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Cat. No.: HY-169931
CAS No.: 1613196-92-1
Target:  

ATM/ATR

Research Areas:  

Cancer

ATR kinase-IN-3 (Compound I-G-28) is a ATR protein kinase inhibitor with the Ki of 0.01 ~ 1 μΜ and can be used for study of cancer .
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Cat. No.: HY-P990921
CAS No.: 2845128-03-0
Synonyms: REGN-9035
HY-P990921 is an NPR1-targeting half-IG G4 -κ/h-CH2-CH3 type human antibody .
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Cat. No.: HY-P990935
CAS No.: 2779564-38-2
Synonyms: IMGN-151 Antibody
Target:  

Antifolate

Research Areas:  

Inflammation/Immunology

HY-P990935 is an FOLR1-targeting half-IG G1 -κ/(scFv -κ-heavy) -h-CH2-CH3 type chimeric antibody .
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Cat. No.: HY-101813R
CAS No.: 147076-36-6
Synonyms: HR325 (Standard)
Laflunimus (Standard) is the analytical standard of Laflunimus. This product is intended for research and analytical applications. Laflunimus (HR325) is an immunosuppressive agent and an analogue of the Leflunomide-active metabolite A77 1726. Laflunimus is an orally active inhibitor of dihydroorotate dehydrogenase (DHODH). Laflunimus suppresses immunoglobulin (Ig) secretion, with IC50 values of 2.5 and 2 μM for IgM and IgG, respectively. Laflunimus also is a prostaglandin endoperoxide H synthase (PGHS) -1 and -2 inhibitor .
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Cat. No.: HY-P990153

Research Areas:  

Inflammation/Immunology

Anti-Mouse TIM-2 Antibody (RMT2-29) is a rat-derived Ig2a λ type antibody inhibitor, targeting to mouse TIM-2. Anti-Mouse TIM-2 Antibody (RMT2-29) reacts with mouse T cell immunoglobulin and mucin domain 2 (TIM-2) and blocks TIM-2 signaling. Anti-Mouse TIM-2 Antibody (RMT2-29) can be used for the research of immunology.
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Cat. No.: HY-111175
CAS No.: 905978-63-4
IG-105 is an orally active and potent tubulin inhibitor that competitively inhibits [ 3H] colchicine binding to tubulin with an IC50 of 0.6 μM and inhibits tubulin polymerization with an IC50 of 3 μM. IG-105 inhibits microtubule polymerization by binding to the colchicine pocket of tubulin, induces G2-M phase arrest, and subsequently activates the caspase cascade through Bcl-2 inactivation and p53 upregulation, inducing apoptosis. IG-105 effectively overcomes multidrug resistance as a non-Pgp substrate. IG-105 can be used for research on leukemia, breast cancer, liver cancer, prostate cancer, lung cancer, melanoma, pancreatic cancer, and colon cancer .
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Cat. No.: HY-167175
CAS No.: 2132345-13-0
Research Areas:  

Others

IG7 is a bioactive ceramide.
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Cat. No.: HY-N16026
CAS No.: 2132345-12-9
Research Areas:  

Others

IG4 is a bioactive ceramide.
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Cat. No.: HY-N16030
CAS No.: 2132345-14-1
Research Areas:  

Others

IG8 is a bioactive ceramide.
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Cat. No.: HY-P4510
CAS No.: 943235-75-4
Target:  

Inhibitory Antibodies

Research Areas:  

Others

SLSLSPG can be obtained from the C-end of the heavy chain of human Igγ-1. SLSLSPG is a common variant in IgG .
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Cat. No.: HY-153658
CAS No.: 1613196-89-6
Research Areas:  

Cancer

ATR-IN-27 (Compound I-G-12) is an ATR inhibitor with a Ki value greater than 0.01 μM but less than 1 μM. ATR-IN-27 sensitizes colorectal cancer cells to Cisplatin (HY-17394) .
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