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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
577 Results for "
IG
" in MedChemExpress (MCE) Product Catalog:
Products (577)
577 Results for "IG" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-P71282A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SEMA3C; Semaphorin-3C; Prev. SEMAE; Uncharacterized Protein SEMA3C; SemE; Semaphorin E; Sema Domain, Immunoglobulin Domain (IG), Short Basic Domain, Secreted, (Semaphorin) 3C; Semaphorin-E; Semaphorin 3C; Sema E
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P76055
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SEMA4A; Semaphorin-4A; Prev. SEMAB; FLJ12287; CORD10; Sema B; SemB; RP35; Sema Domain, Immunoglobulin Domain (IG), Transmembrane Domain (TM) And Short Cytoplasmic Domain, (Semaphorin) 4A; SEMB; Semaphorin 4A; Semaphorin-B
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P74525A
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TGFBI; RGD-Containing Collagen-Associated Protein; Prev. CSD1; Beta IG-H3; Prev. CSD2; RGD-CAP; Prev. CSD3; Transforming Growth Factor, Beta-Induced, 68kDa; Prev. LCD1; Transforming Growth Factor Beta-Induced 68kDa; BIGH3; Transforming Growth Factor Beta
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P70494
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NECTIN1; OFC7; Prev. PVRL1; Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C); Prev. HVEC; Herpesvirus IG-Like Receptor; Prev. ED4; Ectodermal Dysplasia 4 (Margarita Island Type); Nectin-1; Herpes Simplex Virus Type 1 Sensitivity; PRR1; Herpesv
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P71564
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SEMA3A; Sema III; Prev. SEMAD; Semaphorin D; Hsema-I; Semaphorin L; Coll-1; Collapsin 1; SEMA1; Hsema-III; SemD; SEMAIII; Sema Domain, Immunoglobulin Domain (IG), Short Basic Domain, Secreted, (Semaphorin) 3A; COLL1; Semaphorin III; SEMAL; Semaphorin-3A;
Species:
Rat
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P72428
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: VSIR; V-Set Immunoregulatory Receptor; C10orf54; SISP1; VISTA; B7-H5; PD-1H; Dies1; GI24; B7H5; V-Type Immunoglobulin Domain-Containing Suppressor Of T-Cell Activation; V-Set Domain-Containing Immunoregulatory Receptor; V-Domain IG Suppressor Of T Cell Ac
Species:
Mouse
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P70933
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HSPB8; Alpha-Crystallin C Chain; Heat Shock Protein Family B (Small) Member 8; Protein Kinase H11; E2IG1; HSPB8-N1; HSP22; HSPB8-N2; CMT2L; DHMN2; H11; HMN2A; Small Stress Protein-Like Protein HSP22; HMND2; Heat Shock Protein Family B Member 8; MFM13; Hea
Species:
Human
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P70601
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FCGRT; Major Histocompatibility Complex Class I-Like Fc Receptor; Fc Gamma Receptor And Transporter; Neonatal Crystallizable Fc Receptor FcRn Splice Variant 6; Neonatal Fc Receptor; Neonatal Crystallizable Fc Receptor FcRn Splice Variant 5; FcRn; Neonatal Fragment Crystallizable Fc Receptor FcRn; IGG Fc Fragment Receptor Transporter Alpha Chain; Immunoglobulin Receptor, Intestinal, Heavy Chain; IGG Receptor FcRn Large Subunit P51; Neonatal Fc-Receptor For IG; FcgammaRn; FCRN Alpha-Chain; Heavy Chain Of The Major Histocompatibility Complex Class I-Like Fc Receptor; FcRn Alpha Chain; Transmembrane Alpha Chain Of The Neonatal Receptor; Alpha-Chain; Fc Fragment Of IGG, Receptor, Transporter, Alpha; FCRN; Fc Fragment Of IGG Receptor And Transporter; B2M; Beta 2-Microglobulin; Beta-2-Microglobulin; Beta-2-Microglobin; Beta Chain Of MHC Class I Molecules; AMYLD6; Beta 2-Microglobulin Protein; MHC1D4; Human Nkt Tcr Alpha Chain; IMD43; Human Nkt Tcr Beta Chain
Species:
Human
Source:
HEK293
Cat. No.: HY-P99386
CAS No.: 1205533-60-3
Synonyms: MNRP-1685A
Target:
Research Areas:
Cat. No.: HY-122663A
Purity: 99.88%
Target:
Research Areas:
BIO8898 is a potent CD40-CD154 inhibitor. BIO8898 inhibits soluble CD40L binding to CD40-Ig with an IC50 value of 25 µM. BIO8898 inhibits CD40L-induced apoptosis .
Cat. No.: HY-P99371
CAS No.: 2283348-97-8
Synonyms: AK002; Antolimab
Target:
Research Areas:
Target:
Research Areas:
(Rac)-BIO8898 is a CD40-CD154 co-stimulatory interaction inhibitor. (Rac)-BIO8898 inhibits CD154 binding to CD40-Ig with an IC50 of 25 μM .
Cat. No.: HY-P99883
CAS No.: 1399584-78-1
Synonyms: SAR156597
Target:
Research Areas:
Cat. No.: HY-P99595
CAS No.: 1824663-83-3
Synonyms: AGS15E; ASG-15ME; 1vcMMAE
Target:
Research Areas:
Sirtratumab vedotin (ASG15-ME) is an ADC composed of a SLITRK6-specific human gamma 2 antibody (Igγ2) conjugated to a small molecule microtubule disrupting agent, monomethyl auristatin E (MMAE) via a protease-cleavable linker .
Target:
Research Areas:
RU-302 is a pan TAM inhibitor that blocks the interface between the TAM Ig1 ectodomain and the Gas6 Lg domain. RU-302 effectively blocks Gas6-inducible Axl receptor activation with a low micromolar IC50in cell assays, and suppresses lung cancer tumor growth .
Synonyms: HR325
Research Areas:
Laflunimus (HR325) is an immunosuppressive agent and an analogue of the Leflunomide-active metabolite A77 1726. Laflunimus is an orally active inhibitor of dihydroorotate dehydrogenase (DHODH). Laflunimus suppresses immunoglobulin (Ig) secretion, with IC50 values of 2.5 and 2 µM for IgM and IgG, respectively. Laflunimus also is a prostaglandin endoperoxide H synthase (PGHS) -1 and -2 inhibitor .
Target:
Research Areas:
NSC622608 is a V-domain Ig suppressor of T-cell activation (VISTA) ligand with an IC50 value of 4.8 μM .
Cat. No.: HY-171034
CAS No.: 1604678-82-1
Target:
Research Areas:
PQA-18 is a unique PAK2 inhibitor (IC50: 10 nM). PQA-18 has immunosuppressing effects. PQA-18 suppresses IL2, IL4, IL6, and TNFα. PQA-18 inhibits the population of a subset of regulatory T cells and the immunoglobulin (Ig) production against T cell-dependent antigens as well as alleviates dermatitis in mice .
Target:
Research Areas:
VISTA-IN-2 (Compound 1) is an inhibitor of V-domain Ig suppressor of T-cell activation (VISTA). VISTA-IN-2 induces VISTA degradation in cells through an autophagic mechanism. VISTA-IN-2 rescues VISTA-mediated immunosuppression, and enhances antitumor activity of immune cells. VISTA-IN-2 also activates the antitumor immunity and inhibits tumor growth in a CT26 mouse model .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
