1. Protein Tyrosine Kinase/RTK
  2. TAM Receptor
  3. RU-302

RU-302 

Cat. No.: HY-124066
Handling Instructions

RU-302 is a pan TAM inhibitor that blocks the interface between the TAM Ig1 ectodomain and the Gas6 Lg domain. RU-302 effectively blocks Gas6-inducible Axl receptor activation with a low micromolar IC50in cell assays, and suppresses lung cancer tumor growth.

For research use only. We do not sell to patients.

RU-302 Chemical Structure

RU-302 Chemical Structure

CAS No. : 1182129-77-6

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Description

RU-302 is a pan TAM inhibitor that blocks the interface between the TAM Ig1 ectodomain and the Gas6 Lg domain. RU-302 effectively blocks Gas6-inducible Axl receptor activation with a low micromolar IC50in cell assays, and suppresses lung cancer tumor growth[1].

IC50 & Target

TAM, Axl[1]

Molecular Weight

475.53

Formula

C₂₄H₂₄F₃N₃O₂S

CAS No.

1182129-77-6

SMILES

O=C(C1=CC=CC=C1SCC2=C(C)ON=C2C)N3CCN(C4=CC=CC(C(F)(F)F)=C4)CC3

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Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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RU-302
Cat. No.:
HY-124066
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