ATR-IN-27
ATR-IN-27 (Compound I-G-12) is an ATR inhibitor with a Ki value greater than 0.01 μM but less than 1 μM. ATR-IN-27 sensitizes colorectal cancer cells to Cisplatin (HY-17394).
For research use only. We do not sell to patients.
- CAS No.: 1613196-89-6
- Formula: C22H25F2N9O2
- Molecular Weight:485.49
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
ATR-IN-27 is an ATR inhibitor with a Ki value greater than 0.01 μM but less than 1 μM[1].
ATR-IN-27 (96 h) sensitizes the colorectal cancer cell line HCT116 to Cisplatin, with a sensitization value of less than 0.02 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1613196-89-6
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Molecular Weight 485.49
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Formula C22H25F2N9O2
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SMILES
O=C(C1=C2N=CC(F)=CN2N=C1N)NC3=C(N4CCC(CC4)C(N5CCNCC5)=O)C(F)=CN=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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