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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
96 Results for "
IL15
" in MedChemExpress (MCE) Product Catalog:
Products (96)
96 Results for "IL15" in MCE Product Catalog:
Cat. No.: HY-RS06693
Target:
Research Areas:
IL15RA Human Pre-designed siRNA Set A contains three designed siRNAs for IL15RA gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS19780
Target:
Research Areas:
Il15ra Mouse Pre-designed siRNA Set A contains three designed siRNAs for Il15ra gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS26277
Target:
Research Areas:
Il15ra Rat Pre-designed siRNA Set A contains three designed siRNAs for Il15ra gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P810800
Synonyms: Interleukin-15, IL-15, IL15
Cat. No.: HY-P704692
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL15; Interleukin-15; Interleukin 15; MGC9721; IL-15
Species:
Human
Source:
HEK293
Cat. No.: HY-P704691
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL15; Interleukin-15; Interleukin 15; MGC9721; IL-15
Species:
Human
Source:
HEK293
Cat. No.: HY-P704693
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL15; Interleukin-15; Interleukin 15; MGC9721; IL-15
Species:
Human
Source:
HEK293
Cat. No.: HY-P705124
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL15; Interleukin-15; Interleukin 15; MGC9721; IL-15
Species:
Human
Source:
HEK293
Cat. No.: HY-P992030
Target:
Research Areas:
FB102 is an anti-human CD122 (IL-2Rβ) monoclonal antibody with selective activity. FB102 blocks the proliferation and activation of pathogenic NK cells and specific T cell subsets induced by IL-2 and IL-15, without affecting the proliferation of regulatory T cells. FB102 inhibits IL-2/IL-15-induced activation of CD4+ and CD8+ T cells in in vitro disease models. FB102 is applicable to research related to celiac disease .
Cat. No.: HY-P810802
Synonyms: Interleukin-15; IL-15
Cat. No.: HY-100754R
CAS No.: 1792180-81-4
Synonyms: PF-06651600 (Standard)
Research Areas:
Ritlecitinib (Standard) is the analytical standard of Ritlecitinib (HY-100754). This product is intended for research and analytical applications. Ritlecitinib (PF-06651600) is a highly selective, orally active, irreversible covalent JAK3 inhibitor (IC50=33 nM) without inhibitory activity towards JAK1, JAK2, and TYK2 (IC50 >10 μ M). Ritlecitinib rapidly inactivates the JAK3 kinase, and blocks signaling and downstream STAT phosphorylation mediated by common gamma chain cytokines such as IL-2 and IL-15. Ritlecitinib can inhibit Th1/Th17 cell differentiation and function, and effectively suppress preclinical animal models such as alopecia areata, adjuvant-induced arthritis (AIA), and experimental autoimmune encephalomyelitis (EAE) .
Cat. No.: HY-100754CR
CAS No.: 2192215-81-7
Synonyms: PF-06651600 tosylate (Standard)
Research Areas:
Ritlecitinib (tosylate) (Standard) is the analytical standard of Ritlecitinib (tosylate) (HY-100754C). This product is intended for research and analytical applications. Ritlecitinib (PF-06651600) tosylate is a highly selective, orally active, irreversible covalent JAK3 inhibitor (IC50=33 nM) without inhibitory activity towards JAK1, JAK2, and TYK2 (IC50 >10 μ M). Ritlecitinib tosylate rapidly inactivates the JAK3 kinase, and blocks signaling and downstream STAT phosphorylation mediated by common gamma chain cytokines such as IL-2 and IL-15. Ritlecitinib tosylate can inhibit Th1/Th17 cell differentiation and function, and effectively suppress preclinical animal models such as alopecia areata, adjuvant-induced arthritis (AIA), and experimental autoimmune encephalomyelitis (EAE) .
Cat. No.: HY-189364
CAS No.: 88262-44-6
Synonyms: SMC247-9
Target:
Research Areas:
(DL)-3,5-Dimethyltyrosine (SMC247-9) is a selective APOBEC3B inhibitor optimized from SMC247, with an IC50 of 50 pM. (DL)-3,5-Dimethyltyrosine binds to the APOBEC3B protein, reduces intracellular APOBEC3B protein abundance partially through a lysosome-dependent pathway, enhances IL-15 expression in tumor cells, and relieves the suppression of CD8 + T cells by tumor cells in an IL-15-dependent manner. (DL)-3,5-Dimethyltyrosine attenuates tumor- and macrophage-derived chemokine-mediated macrophage chemotaxis and inhibits pathological myeloid inflammatory signaling. (DL)-3,5-Dimethyltyrosine inhibits tumor growth in the immune checkpoint blockade-responsive MC38 syngeneic mouse model and produces synergistic effects with anti-PD-L1 in the immune checkpoint blockade-resistant TC-1 tumor model; it also ameliorates anti-PD-1-exacerbated DSS-induced colitis-like intestinal inflammatory injury. (DL)-3,5-Dimethyltyrosine can be used in research related to tumor immunotherapy .
Cat. No.: HY-P71978
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL15RA; IL-15 Receptor Subunit Alpha; Interleukin 15 Receptor Subunit Alpha; IL15RA Protein; Interleukin-15 Receptor Subunit Alpha; CD215 Antigen; IL-15RA; IL-15R-Alpha; CD215; IL15ra; Interleukin 15 Receptor, Alpha
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P78468
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: IL15RA; IL-15 Receptor Subunit Alpha; Interleukin 15 Receptor Subunit Alpha; IL15RA Protein; Interleukin-15 Receptor Subunit Alpha; CD215 Antigen; IL-15RA; IL-15R-Alpha; CD215; IL15ra; Interleukin 15 Receptor, Alpha
Species:
Human
Source:
HEK293
Cat. No.: HY-P704323
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL15RA; IL-15 Receptor Subunit Alpha; Interleukin 15 Receptor Subunit Alpha; IL15RA Protein; Interleukin-15 Receptor Subunit Alpha; CD215 Antigen; IL-15RA; IL-15R-Alpha; CD215; IL15ra; Interleukin 15 Receptor, Alpha
Species:
Human
Source:
HEK293
Cat. No.: HY-P78154
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: IL15RA; IL-15 Receptor Subunit Alpha; Interleukin 15 Receptor Subunit Alpha; IL15RA Protein; Interleukin-15 Receptor Subunit Alpha; CD215 Antigen; IL-15RA; IL-15R-Alpha; CD215; IL15ra; Interleukin 15 Receptor, Alpha
Species:
Human
Source:
HEK293
Cat. No.: HY-P72592
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL15RA; IL-15 Receptor Subunit Alpha; Interleukin 15 Receptor Subunit Alpha; IL15RA Protein; Interleukin-15 Receptor Subunit Alpha; CD215 Antigen; IL-15RA; IL-15R-Alpha; CD215; IL15ra; Interleukin 15 Receptor, Alpha
Species:
Human
Source:
HEK293
Cat. No.: HY-P705035
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL15RA; IL-15 Receptor Subunit Alpha; Interleukin 15 Receptor Subunit Alpha; IL15RA Protein; Interleukin-15 Receptor Subunit Alpha; CD215 Antigen; IL-15RA; IL-15R-Alpha; CD215; IL15ra; Interleukin 15 Receptor, Alpha
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
