Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
99 Results for "
OPC
" in MedChemExpress (MCE) Product Catalog:
Products (99)
99 Results for "OPC" in MCE Product Catalog:
Cat. No.: HY-A0147
CAS No.: 119914-60-2
Synonyms: OPC-17116; dl-Grepafloxacin
Target:
Research Areas:
Grepafloxacin (OPC-17116) is an oral actively fluoroquinolone antibiotic with potent activity against community-acquired respiratory pathogens including Streptococcus pneumonia. Grepafloxacin has high tissue penetration and a promising pharmacodynamic profile .
Cat. No.: HY-18346R
CAS No.: 137975-06-5
Synonyms: OPC-31260 (Standard)
Research Areas:
Cardiovascular Disease Metabolic Disease Endocrinology Cancer
Mozavaptan (Standard) is the analytical standard of Mozavaptan. This product is intended for research and analytical applications. Mozavaptan (OPC-31260) is a benzazepine derivative and a potent, selective, competitive and orally active vasopressin V2 receptor antagonist with an IC50 of 14 nM. Mozavaptan shows ~85-fold selectivity for V2 receptor over V1 receptor (IC50 of 1.2 μM), and can antagonize the antidiuretic action of arginine vasopressin (AVP) in vivo. Mozavaptan has the potential for hyponatremia, syndrome of inappropriate antidiuretic hormone (SIADH), and congestive heart failure treatment .
Cat. No.: HY-17464S1
CAS No.: 1215541-47-1
Synonyms: OPC-13013-d4
Cat. No.: HY-17495
CAS No.: 51781-06-7
Synonyms: OPC-1085
Target:
Research Areas:
Carteolol is a non-selective β-adrenoceptor antagonist. Carteolol induces apoptosis via a caspase activated and mitochondrial-dependent pathway. Carteolol can be used for glaucoma research .
Cat. No.: HY-17000R
CAS No.: 150683-30-0
Synonyms: OPC-41061 (Standard)
Research Areas:
Tolvaptan (Standard) is the analytical standard of Tolvaptan. This product is intended for research and analytical applications. Tolvaptan is a selective, competitive and orally active vasopressin receptor 2 (V2R) antagonist with an IC50 of 1.28 μM for the inhibition of arginine vasopressin (AVP)-induced platelet aggregation. Tolvaptan induces cell apoposis and affects cell cycle. Tolvaptan can be used for the research of hyponatremia .
Cat. No.: HY-B0360S
CAS No.: 1219409-06-9
Synonyms: OPC12759-d4; Proamipide-d4
Cat. No.: HY-B0360R
CAS No.: 90098-04-7
Target:
Research Areas:
Rebamipide (Standard) is the analytical standard of Rebamipide. This product is intended for research and analytical applications. Rebamipide (OPC12759) is an orally active gastroprotective agent that enhances the production of endogenous PGs (especially intragastric PGE2) by inducing COX-2 expression, thereby protecting the gastric mucosa from injury. Rebamipide exerts anti-proliferative activity against gastric cancer cells. Rebamipide can be used in studies of mucosal protection, gastroduodenal ulcer, gastritis and gastric cancer .
Cat. No.: HY-165492
CAS No.: 103233-65-4
Research Areas:
OPC-14117 is an orally active superoxide radical scavenger that can cross the blood-brain barrier. OPC-14117 inhibits the oxidative stress cascade reaction, significantly reducing the increase in tissue osmotic pressure and alleviating brain edema in the brain contusion model. OPC-14117 blocks the NF-κB-dependent apoptotic pathway in the striatum neuron apoptosis model induced by Quinolinic acid (HY-100807). OPC-14117 can reduce the necrotic volume, protect hippocampal CA3 neurons and restore cognitive function. OPC-14117 can be used to study secondary brain injury and improve neurological prognosis .
Cat. No.: HY-CE01631
Synonyms: OPC4-Coenzyme A
Target:
Research Areas:
OPC4-CoA (OPC4-Coenzyme A) is a coenzyme A derivative .
Cat. No.: HY-CE01632
CAS No.: 2226543-65-1
Synonyms: OPC6-Coenzyme A
Target:
Research Areas:
OPC6-CoA (OPC6-Coenzyme A) is a coenzyme A derivative .
Cat. No.: HY-165493
CAS No.: 121071-92-9
Target:
Research Areas:
Opc-15161 is a novel superoxide generation inhibitor and major degradation product of OPC-15160 .
Cat. No.: HY-167079
CAS No.: 128667-63-0
Target:
Research Areas:
OPC-18750 is a novel positive inotropic agent and 2(lH)-quinolinone derivative. OPC-18750 displays positive inotropic and coronary vasodilating effects .
Cat. No.: HY-167079A
CAS No.: 145364-90-5
Target:
Research Areas:
OPC-18750 hydrochloride has positive inotropic and coronary vasodilatory effects .
Target:
Research Areas:
OPC 4392 hydrochloride is an agonist for presynaptic dopamine receptor and an antagonist for postsynaptic D2 receptor. OPC 4392 reverses the Reserpine (HY-N0480)-induced dopamine accumulation, inhibits Apomorphine (HY-12723)-induced stereotypic and climbing behaviors in mouse models .
Cat. No.: HY-CE00894
Synonyms: 3-Hydroxy-OPC6-coenzyme A
Target:
Research Areas:
3-Hydroxy-OPC6-CoA (3-Hydroxy-OPC6-coenzyme A) is a coenzyme A derivative.
Cat. No.: HY-CE01183
Synonyms: 3-Oxo-OPC4-coenzyme A
Target:
Research Areas:
3-Oxo-OPC4-CoA (3-Oxo-OPC4-coenzyme A) is a derivative of coenzyme A .
Cat. No.: HY-CE01184
Synonyms: 3-Oxo-OPC6-coenzyme A
Target:
Research Areas:
3-Oxo-OPC6-CoA (3-Oxo-OPC6-coenzyme A) is a derivative of coenzyme A .
Cat. No.: HY-17000A
CAS No.: 331947-66-1
Synonyms: (R)-(+)-OPC-41061
Target:
Research Areas:
(R)-(+)-Tolvaptan ((R)-(+)-OPC-41061) is the (R)-(+) enantiomer of Tolvaptan (HY-17000). Tolvaptan (OPC-41061) is a selective, competitive and orally active vasopressin receptor 2 (V2R) antagonist .
Cat. No.: HY-116594
CAS No.: 145969-30-8
Target:
Research Areas:
OPC-14523 free base is an orally active sigma and 5-HT1A receptor agonist, with high affinity for sigma receptors (σ1/2 IC50=47/56 nM), the 5-HT1A receptor (IC50=2.3 nM), and the 5-HT transporter (IC50=80 nM). OPC-14523 free base shows antidepressant-like activity .
Cat. No.: HY-134940S
Synonyms: OPC-167832-d7
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
