54 Results for "

SDF-1

" in MedChemExpress (MCE) Product Catalog:
Products (54)

54 Results for "SDF-1" in MCE Product Catalog:

Cat. No.: HY-186333
CAS No.: 1613021-88-7
Target:  

CXCR

CXCR7 antagonist-2 is a CXCR7 antagonist. CXCR7 antagonist-2 inhibits the binding of SDF-1 and I-TAC chemokines to the CXCR7 receptor. CXCR7 antagonist-2 can be used in research related to tumors, abnormal angiogenesis, inflammation, and other conditions [1].
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Cat. No.: HY-P811332
Synonyms: SDF1, SDF1A, SDF1B, CXCL12, Stromal cell-derived factor 1, SDF-1, hSDF-1, C-X-C motif chemokine 12, Intercrine reduced in hepatomas, Pre-B cell growth-stimulating factor, IRH, hIRH, PBSF

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P991795

Target:  

CXCR

Research Areas:  

Cancer

Anti-Mouse/Human CXCL12 Antibody (K15C) is an antibody targeting SDF-1/CXCL12. Anti-Mouse/Human CXCL12 Antibody (K15C) blocks the biological activity of SDF-1 secreted by cancer-associated fibroblasts. Anti-Mouse/Human CXCL12 Antibody (K15C) inhibits tumor growth, reduces tumor microvessel density, and decreases the proportion of Sca1 +CD31 + endothelial progenitor cells in tumors. Anti-Mouse/Human CXCL12 Antibody (K15C) can be used for research on aggressive human breast cancer. The recommended isotype control is Mouse IgG2a kappa, Isotype Control (HY-P99978) [1].
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Cat. No.: HY-P81089
Synonyms: C-X-C chemokine receptor type 4; CXC-R4; CXCR-4; Stromal cell-derived factor 1 receptor; SDF-1 receptor; Fusin; Leukocyte-derived seven transmembrane domain receptor; LESTR; CD184 antigen; CXCR4_HUMAN.

Host:  

Rabbit

Application:  

WB, IHC-P, IHC-F, ICC/IF, FC, ELISA

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P700546
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CXCR4; SDF-1 Receptor; C-X-C Motif Chemokine Receptor 4; CD184 Antigen; LESTR; LAP-3; Fusin; NPYRL; HM89; FB22; C-X-C Chemokine Receptor Type 4; LCR1; D2S201E; Seven-Transmembrane-Segment Receptor, Spleen; NPYY3R; Chemokine (C-X-C Motif), Receptor 4 (Fusi
Species:  
Human
Source:  
E. coli Cell-free
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Cat. No.: HY-P72160
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CXCR4; SDF-1 Receptor; C-X-C Motif Chemokine Receptor 4; CD184 Antigen; LESTR; LAP-3; Fusin; NPYRL; HM89; FB22; C-X-C Chemokine Receptor Type 4; LCR1; D2S201E; Seven-Transmembrane-Segment Receptor, Spleen; NPYY3R; Chemokine (C-X-C Motif), Receptor 4 (Fusi
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P72159
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CXCR4; SDF-1 Receptor; C-X-C Motif Chemokine Receptor 4; CD184 Antigen; LESTR; LAP-3; Fusin; NPYRL; HM89; FB22; C-X-C Chemokine Receptor Type 4; LCR1; D2S201E; Seven-Transmembrane-Segment Receptor, Spleen; NPYY3R; Chemokine (C-X-C Motif), Receptor 4 (Fusi
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P702258
Purity:  Purity analysis by SDS-PAGE is not available for VLP proteins.
Synonyms: CXCR4; SDF-1 Receptor; C-X-C Motif Chemokine Receptor 4; CD184 Antigen; LESTR; LAP-3; Fusin; NPYRL; HM89; FB22; C-X-C Chemokine Receptor Type 4; LCR1; D2S201E; Seven-Transmembrane-Segment Receptor, Spleen; NPYY3R; Chemokine (C-X-C Motif), Receptor 4 (Fusi
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-N9858
CAS No.: 911052-87-4
Herpetin is an active lignan. Herpetin acts as a bone marrow mesenchymal stem cell inducer that activates the SDF-1/CXCR4 axis and the Wnt/β-catenin pathway. Herpetin is applicable to research related to acute liver injury [1] .
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Cat. No.: HY-P84972
Synonyms: CXCR4; FB22; HM89; LAP3; LCR1; NPYR; WHIM; CD184; LAP-3; LESTR; NPY3R; NPYRL; WHIMS; HSY3RR; NPYY3R; WHIMS1; D2S201E; C-X-C chemokine receptor type 4 antibody; CD184 antibody; CD184 antigen antibody; Chemokine; C X C motif; receptor 4 antibody; Chemokine CXC Motif Receptor 4 antibody; CXC-R4 antibody; CXCR-4 antibody; CXCR4 antibody; CXCR4_HUMAN antibody; D2S201E antibody; FB22 antibody; Fusin antibody; HM89 antibody; HSY3RR antibody; LAP 3 antibody; LAP3 antibody; LCR1 antibody; LESTR antibody; Leukocyte derived seven transmembrane domain receptor antibody; Leukocyte-derived seven transmembrane domain receptor antibody; Lipopolysaccharide associated protein 3 antibody; Neuropeptide Y receptor Y3 antibody; NPY3R antibody; NPYR antibody; NPYRL antibody; NPYY3 antibody; NPYY3R antibody; Probable G protein coupled receptor lcr1 homolog antibody; SDF 1 receptor antibody; SDF-1 receptor antibody; SEVEN-TRANSMEMBRANE-SEGMENT RECEPTOR antibody; Stromal cell derived factor 1 receptor antibody; Stromal cell-derived factor 1 receptor antibody; WHIM antibody; WHIMS antibody;
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Cat. No.: HY-P991790

Target:  

CXCR

Research Areas:  

Others

Anti-Human/Monkey CXCR4 Antibody (12G5) reacts with human and monkey CXCR4. Anti-Human/Monkey CXCR4 Antibody (12G5) blocks the cognate ligand, CXCL12/SDF-1, and gp120/160 from binding to CXCR4. Recommend Isotype Controls: Mouse IgG2a kappa, Isotype Control (HY-P99978) [1].
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Cat. No.: HY-P12114
Research Areas:  

Infection Cancer

S3 peptide is a multifunctional synthetic peptide that acts as a LIMK1 inhibitor with an IC50 of 40 μg/mL. S3 peptide blocks cofilin phosphorylation and SDF-1α (HY-P4911)-induced T cell chemotaxis, and reduces viral particle production of HIV-1 and M-PMV. S3 peptide forms dimers via intermolecular disulfide bonds to bind and disrupt LPS micelles, exerting anti-Gram-negative bacterial activity. S3 peptide serves as a targeting moiety for NKA α1 and is used for the construction of PET tracers. S3 peptide is applicable to research related to HIV-1 infection, M-PMV infection, breast cancer, liver cancer and non-small cell lung cancer [1] .
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Cat. No.: HY-P72674
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CXCR4; SDF-1 Receptor; C-X-C Motif Chemokine Receptor 4; CD184 Antigen; LESTR; LAP-3; Fusin; NPYRL; HM89; FB22; C-X-C Chemokine Receptor Type 4; LCR1; D2S201E; Seven-Transmembrane-Segment Receptor, Spleen; NPYY3R; Chemokine (C-X-C Motif), Receptor 4 (Fusin); HSY3RR; Seven Transmembrane Helix Receptor; NPY3R; Neuropeptide Y Receptor Y3; CD184; Neuropeptide Y3 Receptor; NPYR; Chemokine Receptor 4; Leukocyte-Derived Seven Transmembrane Domain Receptor; WHIMS1; Lipopolysaccharide-Associated Protein 3; CXCR-4; Stromal Cell-Derived Factor 1 Receptor; CXC-R4; Chemokine (C-X-C Motif) Receptor 4; WHIMS; LPS-Associated Protein 3; WHIM
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P991744

Target:  

CXCR

Research Areas:  

Cancer

Anti-Mouse CXCR4 Antibody is a monoclonal antibody that specifically recognizes murine CXCR4 (C-X-C chemokine receptor 4), also known as fusin or CD184. CXCR4 is a seven-transmembrane G protein–coupled receptor whose principal endogenous ligand is CXCL12 (stromal cell–derived factor-1α, SDF-1α) and is widely expressed in hematopoietic cells, endothelial cells, neurons, as well as embryonic and adult stem cells. The CXCR4–CXCL12 signaling axis activates multiple downstream pathways, including ERK1/2, Ras, p38 MAPK, PLC/MAPK, and SAPK/JNK, thereby regulating cell survival, proliferation, migration, and stemness maintenance. Aberrant overexpression of CXCR4 is closely associated with poor prognosis and metastasis in various cancers, with CXCR4-positive tumor cells preferentially home to CXCL12-rich tissues such as the liver, bone marrow, lung, and lymph nodes. Accordingly, CXCR4 and its CXCL12-related antagonists emerge as attractive targets for experimental anticancer therapy. Anti-Mouse CXCR4 Antibody is generated using a cell-based immunization and screening strategy and exhibits high affinity for both endogenous and exogenous murine CXCR4. Anti-Mouse CXCR4 Antibody can be used for thestudy of chronic lymphocytic leukemia and multiple myeloma [1].
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