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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
232 Results for "
glaucoma
" in MedChemExpress (MCE) Product Catalog:
Products (232)
232 Results for "glaucoma" in MCE Product Catalog:
Synonyms: NCX 470
Target:
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Bimatoprost grenod (NCX 470) is a second-generation nitric oxide (NO)-donating prostaglandin analogue. Bimatoprost grenod effectively lowers intraocular pressure (IOP) in animal models of ocular hypertension and glaucoma by activating bimatoprost-mediated uveoscleral outflow and NO mediated conventional outflow. Bimatoprost grenod can be used for the research of cular hypertension and glaucoma .
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LIMK-IN-1 (Compound 14) is an inhibitor of LIM-Kinase (LIMK), with IC50s of 0.5 nM and 0.9 nM for LIMK1 and LIMK2, respectively. LIMK-IN-1 can be used for ocular hypertension and associated glaucoma research .
Cat. No.: HY-P10019
CAS No.: 2243292-26-2
Synonyms: NLY01
Target:
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Synonyms: INO-8875
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Trabodenoson (INO-8875), an adenosine mimetic, is a highly selective Adenosine A1 receptor agonist. Trabodenoson (INO-8875) is used in the study for Primary Open-Angle Glaucoma .
Cat. No.: HY-135163
CAS No.: 913258-34-1
Synonyms: (5E)-Latanoprost; 5,6-trans-Latanoprost
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trans-Latanoprost (5,6-trans-Latanoprost) is the trans isomer of Latanoprost (HY-B0577). trans-Latanoprost is promising for research of glaucoma and high eye pressure .
Cat. No.: HY-128538
CAS No.: 1262873-06-2
Synonyms: ONO-9054
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Sepetaprost (ONO-9054) is a dual agonist of the prostaglandin E3 receptor and prostaglandin F receptor. Sepetaprost reduces intraocular pressure in animal models. Sepetaprost is applicable for research on ocular hypertension and open-angle glaucoma .
Cat. No.: HY-113089A
Purity: 98.55%
Synonyms: H-Glu(H-Lys-OH)-OH TFA; γ-Glu-ε-Lys TFA
Target:
Cat. No.: HY-P99695
CAS No.: 285985-06-0
Synonyms: CAT-152
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Cat. No.: HY-B0588A
CAS No.: 150937-43-2
Synonyms: AL-4862 hydrochloride
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Brinzolamide (AL-4862) hydrochloride is a selective carbonic anhydrase II inhibitor with an IC50 value of 3.2 nM. Brinzolamide hydrochloride reduces intraocular pressure (IOP) by inhibiting ciliary CA-II and decreasing atrial fluid secretion. Brinzolamide hydrochloride can be used in glaucoma disease research .
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PGN-9856 is a selective and high affinity (pKi ≥ 8.3) ligand at EP2 receptor. PGN-9856 is a potetn and non-prostanoid EP2 receptor agonist (pEC50 ≥ 8.5). PGN-9856 shows anti-inflammatory and anti-glaucoma activities .
Cat. No.: HY-121166
CAS No.: 93221-48-8
Synonyms: (S)-Betaxolol
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Levobetaxolol is a potent and high affinity β-adrenergic antagonist with IC50 values of 33.2, 2970, 709 nM for guinea pig atrial β1, tracheal β2 and rat colonic β3 receptors, respectively. Levobetaxolol reduces IOP (intraocular pressure). Levobetaxolol exhibits a micromolar affinity for L-type Ca21-channels. Levobetaxolol decreases the effects of ischaemia/reperfusion injury in rats. Levobetaxolol has the potential for the research of glaucoma .
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17-Phenyl trinor PGF2α isopropyl ester is a FP receptor agonist and intraocular pressure-lowering agent. 17-Phenyl trinor PGF2α isopropyl ester induces iris sphincter contraction, reduces intraocular pressure and pupil diameter, causes no ocular irritation, and only leads to mild conjunctival hyperemia. 17-Phenyl trinor PGF2α isopropyl ester is applicable to relevant research on glaucoma .
Cat. No.: HY-121398
CAS No.: 52365-63-6
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Echothiopate iodide is a potent hBChE (human butyrylcholinesterase) inhibitor. Echothiopate iodide is a long-acting anticholinesterase agent. Echothiopate iodide can be used for glaucoma research .
Cat. No.: HY-106331A
CAS No.: 126453-94-9
Synonyms: MK-927; (Rac)-MK 417
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(Rac)-Sezolamide hydrochloride (MK-927; (Rac)-MK 417) is a carbonic anhydrase inhibitor (CAI) (Ki: 12.0 nM). (Rac)-Sezolamide hydrochloride has a topical intraocular pressure (IOP) lowering effect. (Rac)-Sezolamide hydrochloride can be used in glaucoma research .
Cat. No.: HY-178017
Research Areas:
BChE/hCA II-IN-1 (Compound 20) is a dual-functional inhibitor of Butyrylcholinesterase (BChE) and human carbonic anhydrase II (hCA II) with IC50s of 76.50 and 10.69 μM for BChE and hCA II, respectively. BChE/hCA II-IN-1 can be used for neurodegenerative diseases like Alzheimer's and glaucoma research .
Cat. No.: HY-129781
CAS No.: 96803-89-3
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L-650719 is a topical carbonic anhydrase inhibitor (CAI) with a Ki of 10 nM for CA II. L-650719 has shown good intraocular pressure-lowering effects in a rabbit model. L-650719 may be used in glaucoma research .
Cat. No.: HY-152270
CAS No.: 19825-63-9
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Pirnabine is a cannabinoid receptor ligand. Pirnabine can be used for the research of glaucoma .
Cat. No.: HY-169137
CAS No.: 90581-63-8
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Falintolol is a β-adrenergic receptor antagonist that can be used in glaucoma research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
