Echothiopate iodide
Echothiopate iodide is a potent hBChE (human butyrylcholinesterase) inhibitor. Echothiopate iodide is a long-acting anticholinesterase agent. Echothiopate iodide can be used for glaucoma research.
For research use only. We do not sell to patients.
- CAS No.: 513-10-0
- Formula: C9H23INO3PS
- Molecular Weight:383.23
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 513-10-0
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Molecular Weight 383.23
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Formula C9H23INO3PS
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SMILES
O=P(SCC[N+](C)(C)C)(OCC)OCC.[I-]
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Synonyms
Echothiophate iodide
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Nachon F, et al. Role of water in aging of human butyrylcholinesterase inhibited by echothiophate: the crystal structure suggests two alternative mechanisms of aging. Biochemistry. 2005 Feb 1;44(4):1154-62. [Content Brief]
[2]. HUMPHREYS JA, et al. Systemic effects produced by echothiophate iodide in treatment of glaucoma. Arch Ophthalmol. 1963 Jun;69:737-43. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)