112 Results for "

CTL

" in MedChemExpress (MCE) Product Catalog:
Products (112)

112 Results for "CTL" in MCE Product Catalog:

Referencia número: HY-106374
No. CAS: 673478-49-4
Target:  

VEGFR

Áreas de investigación:  

Cancer

Elpamotide is an epitope peptide derived from VEGFR2. Elpamotide induces cytotoxic T lymphocytes (CTLs) to kill VEGFR2-expressing endothelial cells. Elpamotide has potential immunostimulatory and antineoplastic activities. Elpamotide can be used in the research of cancer, such as pancreatic cancer .
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Referencia número: HY-P1855
No. CAS: 160790-21-6
Target:  

EGFR

Áreas de investigación:  

Cancer

HER2/neu (654-662) GP2 is a nine amino acid peptide derived from the human epidermal growth factor receptor 2 (HER2/nue, 654–662), induces HLA-A2-restricted cytotoxic T lymphocytes (CTL) reactive to various epithelial cancers .
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Referencia número: HY-P2495
No. CAS: 2648610-97-1
Áreas de investigación:  

Cancer

OVA (241-270), a non-specific cytotoxic T lymphocyte (CTL) peptide, is a fragmented peptide of OVA (ovalbumin) antigen .
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Referencia número: HY-P1881
No. CAS: 160040-04-0
Target:  

HPV

Áreas de investigación:  

Cancer

HPV16-E711-20 epitope is a well-known HLA-A *0201-restricted human cytotoxic T lymphocyte (CTL) epitope of the HPV16 E7 protein that shows high-affinity binding to HLA-A2 in vitro. HPV16 CTL epitopes may be good candidates for the development of an effective peptide-based antitumor vaccine .
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Referencia número: HY-P1757
No. CAS: 147468-65-3
Target:  

HIV

Áreas de investigación:  

Infection

HIV p17 Gag (77-85) is an HLA-A*0201(A2)-restricted CTL epitope, used in the research of anti-HIV .
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Referencia número: HY-P99100A
No. CAS: 2556646-63-8
Synonyms: CLT-002 (Powder)

Áreas de investigación:  

Cancer

Visugromab (CTL-002) (Powder) is a GDF-15 neutralizing IgG4 mAb. Visugromab (Powder) has synergistic anticancer activity with the anti-PD1 antibody Nivolumab (HY-P9903) and can effectively act on PD-1/PD-L1 relapsed/refractory metastatic solid tumors. Recommend Isotype Controls: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) .
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Referencia número: HY-P990928
No. CAS: 2839556-21-5
Synonyms: APVO-436

Target:  

CD3 Interleukin Related

Áreas de investigación:  

Inflammation/Immunology Cancer

Mipletamig (APVO-436) is a bispecific CD123 x CD3 monoclonal antibody. Mipletamig simultaneously binds to both CD3-expressing T cells and CD123-expressing cancer cells, thereby crosslinking CD123-expressing tumor cells and cytotoxic T lymphocytes (CTLs). This results in the activation and proliferation of T-cells and causes CTL-mediated cell lysis of CD123-expressing tumor cells. Mipletamig can be used for the study of acute myeloid leukemia (AML) .
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Referencia número: HY-P10610
No. CAS: 155314-25-3
Target:  

MDM-2/p53

Áreas de investigación:  

Cancer

Peptide 234CM is a peptide containing isoleucine at position 3, corresponding to the sequence of a point mutation in p53 codon 234. Peptide 234CM induces potent cytotoxic T cell (CTL) and antitumor immune responses against mutant p53 .
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Referencia número: HY-P4032
No. CAS: 160214-01-7
Target:  

HCV

Áreas de investigación:  

Inflammation/Immunology

HCV Peptide (35-44), a HCV core protein at positions 35 to 44, is a HLA-A2-restricted CTL epitope. HCV Peptide (35-44) inhibits NK cell activity via two distinct mechanisms, directly via KIR2DL2/3, and synergistically via the CD94:NKG2A receptor .
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Referencia número: HY-P10593
No. CAS: 126779-14-4
Áreas de investigación:  

Cancer

Influenza A NP (383-391) (HLA-B27) is a peptide sequence derived from tetanus toxin. Influenza A NP (383-391) (HLA-B27) is a broadly immunogenic CD4+ T helper cell epitope that enhances CD8+ cytotoxic T lymphocyte (CTL) responses. Influenza A NP (383-391) (HLA-B27) can be used in breast cancer research .
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Referencia número: HY-P10497
No. CAS: 200124-17-0
Target:  

Bacterial

Áreas de investigación:  

Infection Inflammation/Immunology

EBV BZLF1 (190-197) is an immunodominant CEF-controlling peptide derived from Epstein-Barr virus (EBV). EBV BZLF1 (190-197) is a suitable epitope for CD8+ T cells to stimulate the release of IFNg. CTL responses to EBV BZLF1 (190-197) are diverse and cross-recognize similar peptides from both host self-proteins and bacterial proteins. EBV BZLF1 (190-197) can be used to study autoimmune diseases .
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Referencia número: HY-P10497A
Target:  

Bacterial

Áreas de investigación:  

Infection Inflammation/Immunology

EBV BZLF1 (190-197) TFA is an immunodominant CEF-controlling peptide derived from Epstein-Barr virus (EBV). EBV BZLF1 (190-197) TFA is a suitable epitope for CD8+ T cells to stimulate the release of IFNg. CTL responses to EBV BZLF1 (190-197) TFA are diverse and cross-recognize similar peptides from both host self-proteins and bacterial proteins. EBV BZLF1 (190-197) TFA can be used to study autoimmune diseases .
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Referencia número: HY-149540
Áreas de investigación:  

Cancer

CTL-06 is an inhibitor of Fatty Acid Synthase (FASN) (IC50: 3 μM) and can induce apoptosis. CTL-12 blocks the cell cycle in the Sub-G1/S phase, upregulates the expression of caspase-9 and the apoptosis marker Bax, and downregulates the anti-apoptotic marker Bcl-xL. CTL-12 inhibits de novo lipogenesis, blocks the metabolic demands of tumor cells, and is commonly used in breast and colorectal cancer research .
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Referencia número: HY-149541
Áreas de investigación:  

Cancer

CTL-12 is an inhibitor of fatty acid synthase (FASN) (IC50: 2.5 μM) and can induce apoptosis. CTL-12 blocks the cell cycle in the Sub-G1/S phase, upregulates the expression of caspase-9 and the apoptosis marker Bax, and downregulates the anti-apoptotic marker Bcl-xL. CTL-12 inhibits de novo lipogenesis, blocks the metabolic demands of tumor cells, and is commonly used in breast and colorectal cancer research .
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Referencia número: HY-162637
No. CAS: 3047448-30-3
Target:  

Glycosidase

Áreas de investigación:  

Metabolic Disease

CTL26 is a potent and orally active α-glucosidase inhibitor with an IC50 value of 2.81 µM. CTL26 shows anti-diabetic efficacy .
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Referencia número: HY-P10245
No. CAS: 406477-46-1
Target:  

RSV

Áreas de investigación:  

Inflammation/Immunology

Fusion glycoprotein 92-106 is a polypeptide from fusion protein of respiratory syncytial virus (RSV). Fusion glycoprotein 92-106 acts as MHC class I-restricted CTL epitope, that all 15 amino acids are required for efficient recognition by cytotoxic T lymphocyte (CTL) .
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Referencia número: HY-P1870
No. CAS: 92915-80-5
Target:  

Inhibitory Antibodies

Áreas de investigación:  

Inflammation/Immunology

OVA sequence (323-336) is a cognate helper T-lymphocyte peptide that is employed to enhance CTL epitope immunogenicity.
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Referencia número: HY-P5501
No. CAS: 145253-17-4
Target:  

Inhibitory Antibodies

Áreas de investigación:  

Others

Influenza A NP (366-374) is a biological active peptide. (H-2Db restricted CTL epitope)
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Referencia número: HY-105039
No. CAS: 181477-43-0
Synonyms: G209-2M; GP100:209-217(210M); MPS-22
Target:  

Inhibitory Antibodies

Áreas de investigación:  

Cancer

Disomotide (G209-2M) is a melanoma antigen that enhances the generation of cytotoxic T lymphocytes (CTL) recognizing native G209 as well as melanoma .
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Referencia número: HY-153209
Áreas de investigación:  

Others

Adjuvant-4 is a vaccine adjuvant that enhances antigen-specific antibody titers and cytotoxic T lymphocyte (CTL) responses . Adjuvant is generally an oil-in-water emulsifier of mineral oil and mannitol monooleate.
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