Disomotide (Synonyms: G209-2M; GP100:209-217(210M); MPS-22)

Cat. No.: HY-105039: FAQs
Data Sheet Handling Instructions

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Disomotide (G209-2M) is a melanoma antigen that enhances the generation of cytotoxic T lymphocytes (CTL) recognizing native G209 as well as melanoma.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Disomotide Chemical Structure

CAS No. : 181477-43-0

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Description	Disomotide (G209-2M) is a melanoma antigen that enhances the generation of cytotoxic T lymphocytes (CTL) recognizing native G209 as well as melanoma^[1]^[2].
In Vitro	For Ag activation, PBMCs from immunized patients are cultured for 6 days with Disomotide (G209-2M) peptide (1 μM)^[2]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Disomotide Related Antibodies
Molecular Weight	1035.21
Formula	C₄₇H₇₄N₁₀O₁₄S
CAS No.	181477-43-0
Sequence	Ile-Met-Asp-Gln-Val-Pro-Phe-Ser-Val
Sequence Shortening	IMDQVPFSV
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (258 KB) Handling Instructions (2659 KB)
References	[1]. Yang S, et al. Antimelanoma activity of CTL generated from peripheral blood mononuclear cells after stimulation with autologous dendritic cells pulsed with melanoma gp100 peptide G209-2M is correlated to TCR avidity. J Immunol. 2002 Jul 1;169(1):531-9. [Content Brief] [2]. Ahmadzadeh M, et al. IL-2 and IL-15 each mediate de novo induction of FOXP3 expression in human tumor antigen-specific CD8 T cells. J Immunother. 2007 Apr;30(3):294-302. [Content Brief]

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Disomotide181477-43-0G209-2M GP100:209-217(210M) MPS-22MPS22MPS 22MPS-22OthersInhibitorinhibitorinhibit

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Disomotide (Synonyms: G209-2M; GP100:209-217(210M); MPS-22)

Disomotide Related Antibodies

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Biological Activity

Purity & Documentation

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