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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
47 Results for "
menopause
" in MedChemExpress (MCE) Product Catalog:
Products (47)
47 Results for "menopause" in MCE Product Catalog:
Cat. No.: HY-181682
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NK3R antagonist-1 is an orally active neurokinin-3 receptor (NK3R) antagonist with an IC50 of 53.61 nM. NK3R antagonist-1 reduces plasma luteinizing hormone (LH) levels in ovariectomized rat models. NK3R antagonist-1 is applicable to research related to menopausal hot flushes .
Synonyms: ent-β-Estradiol; ent-17β-Estradiol; ent-17β-Oestradiol
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Ent-Estradiol is the enantiomer of Estradiol (HY-B0141). Ent-Estradiol is a highly selective estrogen receptor ligand, but does not possess estrogenic activity. Ent-Estradiol displays IC50 values of 24.9 nM, 9.59 nM and 8.17 nM for human, rat and mouse ERβ, and 151 nM, 246 nM and 268 nM for human, rat and mouse ERα, respectively. Ent-Estradiol can be used for the study of menopausal physiological changes .
Cat. No.: HY-187871
CAS No.: 2854332-29-7
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Neurological Disease Metabolic Disease Inflammation/Immunology Endocrinology
Grexenetant (compound I) is a NK-3 receptor antagonist. Grexenetant can be used in the research of diseases mediated by NK-3 receptors, such as depression, anxiety, psychosis, schizophrenia, psychotic disorders, bipolar disorder, cognitive impairment, Parkinson's disease, Alzheimer's disease, attention deficit hyperactivity disorder, pain, convulsions, obesity, inflammatory diseases, vomiting, preeclampsia, airway-related diseases, reproductive disorders, sex hormone-dependent diseases, gynecological diseases, and menopausal syndrome .
Cat. No.: HY-W744064
CAS No.: 2519535-80-7
Cat. No.: HY-117076A
CAS No.: 61665-15-4
Synonyms: (R)-R 2858; RU 16117
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(R)-Moxestrol ((R)-R 2858; RU 16117) is an orally active weak partial agonist-antagonist of estrogen receptor (ER). (R)-Moxestrol binds to estrogen receptor to form a rapidly dissociating complex, reduces the levels of estrogen and prolactin receptor, exerts weak estrogenic effects at low doses, and displays anti-estrogenic effects at high doses or when competing with Estradiol (E2) (HY-B0141). (R)-Moxestrol can be used in research related to breast cancer and postmenopausal estrogen deficiency (menopausal symptoms, severe osteoporosis) .
Cat. No.: HY-186284
CAS No.: 2245952-60-5
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EGX358 is a selective, orally active estrogen receptor β (ERβ) agonist with an EC50 of 27.4 nM for ERβ. EGX358 enhances object recognition ability, spatial memory and memory consolidation, and attenuates drug-induced vasomotor responses. EGX358 alleviates partial uterine atrophy without inducing uterine hypertrophy, while it does not alter anxiety-like behavior, depression-like behavior or body weight. EGX358 can be used in research related to Alzheimer's disease and menopause .
Cat. No.: HY-W744272
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
