416 Results for "

proline editing

" in MedChemExpress (MCE) Product Catalog:
Products (416)

416 Results for "proline editing" in MCE Product Catalog:

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Cat. No.: HY-Y0252S1
CAS No.: 65807-22-9
L-Proline-d3 is the deuterium labeled L-Proline. L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins.
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Cat. No.: HY-Y0755
CAS No.: 102195-79-9
Research Areas:  

Cancer

N-Boc-cis-4-hydroxy-L-proline methyl ester is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Boc-cis-4-hydroxy-L-proline methyl ester is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2
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Cat. No.: HY-Y0252S5
CAS No.: 39063-89-3
L-Proline-d7 is the deuterium labeled L-Proline. L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins.
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Cat. No.: HY-101402
CAS No.: 53109-32-3
Synonyms: Cyclohistidyl-proline; Histidylproline diketopiperazine
Cyclo(his-pro) (Cyclo(histidyl-proline)) is an orally active cyclic dipeptide structurally related to tyreotropin-releasing hormone . Cyclo(his-pro) could inhibit NF-κB nuclear accumulation. Cyclo(his-pro) can cross the brain-blood-barrier and affect diverse inflammatory and stress responses .
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Cat. No.: HY-159078
CAS No.: 2607139-80-8
Purity:  98.42%
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

PolQi1 is a selective inhibitor targeting the Polθ domain of DNA polymerase. PolQi1 inhibits the Polθ-mediated microhomology end joining (TMEJ/alt-EJ) pathway, reducing insertion/deletion (Indels) and imprecise editing events during DNA repair. PolQi1 can enhance the efficiency and accuracy of homology-directed repair (HDR) or Prime editing, and reduce off-target effects; and in combination with DNA-PK inhibitor AZD-7648 (HY-111783), exert efficient genome editing capabilities with dual pathway regulation. PolQi1 can be mainly used in gene editing research (such as CRISPR-Cas9 or Prime editing system optimization) to improve the precision editing efficiency of difficult-to-edit cells (such as primary hepatocytes and mouse embryos) .
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Cat. No.: HY-75087
CAS No.: 344-25-2
Synonyms: (+)-(R)-proline; (R)-(+)-proline; (R)-2-Carboxypyrrolidine; (R)-proline
(R)-pyrrolidine-2-carboxylic acid ((+)-(R)-Proline) is a proline isomer that exhibits high renal and hepatotoxicity in rats. (R)-pyrrolidine-2-carboxylic acid can be used to study amino acid metabolism and toxicity mechanisms .
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Cat. No.: HY-40114
CAS No.: 15761-39-4
Boc-L-proline is an amino acid derivative. As an important intermediate in organic synthesis, Boc-L-proline can be used for peptide synthesis .
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Cat. No.: HY-21754
CAS No.: 475-11-6
Synonyms: N-Methyl-L-proline
Hygric acid (N-Methyl-L-proline) is a proline analog that is found in bergamot, various citrus juices, and alfalfa seedlings .
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Cat. No.: HY-40136
CAS No.: 618-27-9
cis-4-Hydroxy-L-proline is an orally active proline analog and collagen production inhibitor. cis-4-Hydroxy-L-proline inhibits cell growth by preventing the deposition of triple helical collagen on the cell layer. cis-4-Hydroxy-L-proline inhibits N-nitrosomethylurea-induced breast tumor growth. cis-4-Hydroxy-L-proline improves lung compliance and reduces prostate weight. cis-4-Hydroxy-L-proline can be used in the study of hypoxic pulmonary hypertension .
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Cat. No.: HY-15183
CAS No.: 223666-07-7
Purity:  99.64%
Target:  

Collagen

Research Areas:  

Cancer

Collagen proline hydroxylase inhibitor is a collagen proline hydroxylase inhibitor, which can be used as an anti-fibrotic agent .
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Cat. No.: HY-W016042
CAS No.: 13504-85-3
N-Cbz-Hydroxy-L-proline is a chiral N-Cbz-protected amino acid derivative. N-Cbz-Hydroxy-L-proline is commonly used in the synthesis of polypeptides and pharmaceutical intermediates. N-Cbz-Hydroxy-L-proline undergoes decarboxylation under AlCl3/HFIP conditions .
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Cat. No.: HY-111659
CAS No.: 20930-58-9
Purity:  97.64%
Synonyms: Histidyl-proline; H-His-Pro-OH
Target:  

Inhibitory Antibodies

Research Areas:  

Others

His-Pro (Histidyl-proline) is a dipeptide consisting of histidyl and proline .
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Cat. No.: HY-Y0252S4
CAS No.: 202407-23-6
L-Proline- 13C5,1- 15N is the 13C- and 15N-labeled L-Proline. L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins.
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Cat. No.: HY-34666
CAS No.: 3398-22-9
(4S)-4-Hydroxy-D-proline is a D-proline derivative and aglycon core for synthesis of cell wall O-glycans of the green alga Chlamydomonas reinhardtii .
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Cat. No.: HY-W015897
CAS No.: 4043-88-3
Research Areas:  

Others

3,4-Dehydro-L-proline is aamino acids and their derivatives.
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Cat. No.: HY-W012908
CAS No.: 609-36-9
Research Areas:  

Infection Cancer

DL-Proline is a racemic mixture of D-Proline and L-Proline, belonging to cyclic imino acids with a five-membered ring structure. DL-Proline serves as a key structural unit in peptide synthesis. DL-Proline stabilizes β-turn conformations and affects the secondary structure of peptide segments. DL-Proline exhibits biological activities such as regulating peptide segment conformations and enhancing cyclic peptide stability. DL-Proline can be used in research on diseases related to peptide structure and function, including cancer and bacterial infections .
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Cat. No.: HY-W004114
CAS No.: 68-95-1
N-Acetyl-L-proline is an N-acetylated amino acid derivative of L-proline (HY-Y0252), as well as a stereospecific substrate of N-acyl-L-proline-acylase. N-Acetyl-L-proline can be used for the synthesis of the non-steroidal anti-inflammatory drug Aceprol .
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Cat. No.: HY-Y0252S3
CAS No.: 81202-06-4
L-Proline- 13C is the 13C-labeled L-Proline. L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins.
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Cat. No.: HY-144250S
Glycyl-L-proline- 15N,d2 (trifluoroacetate) is a 15N-labeled and deuterium labeled Glycyl-L-proline .
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Cat. No.: HY-76105
CAS No.: 114676-59-4
Research Areas:  

Cancer

D-Proline, 4-hydroxy-, methyl ester hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). D-Proline, 4-hydroxy-, methyl ester hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2
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