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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
125 Results for "
sphingolipid
" in MedChemExpress (MCE) Product Catalog:
Products (125)
125 Results for "sphingolipid" in MCE Product Catalog:
Cat. No.: HY-165550
CAS No.: 134053-67-1
Synonyms: C22-D-erythro-Sphingosine
Research Areas:
Sphingosine (C22-D-erythro-Sphingosine) is a metabolite of sphingolipid and a pro-Apoptotic signaling messenger. Sphingosine induces apoptosis via Caspase-dependent, mitochondria-dependent and lysosomal affinity detergent pathways, downregulates Bcl-2 and Bcl-xL, and truncates Bid and Bax. Sphingosine is used for cancer research .
Cat. No.: HY-115708S
CAS No.: 2011762-87-9
Cat. No.: HY-153830S
CAS No.: 2097249-92-6
Synonyms: C16 Lactosylceramide (d18:1/16:0)-d3
Synonyms: L-threo-Sphingosylphosphorylcholine
Target:
Research Areas:
L-threo Lysosphingomyelin (d18:1) (L-threo-Sphingosylphosphorylcholine) is an endogenous bioactive sphingolipid. L-threo Lysosphingomyelin (d18:1) is a potent S1P receptor agonist with EC50s of 19.3, 131.8, and 313.3 nM for hS1P1, hS1P3, and hS1P2, respectively .
Cat. No.: HY-178174
Target:
Research Areas:
MGB4 is a DNA minor groove binder. MGB4 binds to ARE-containing DNA and inhibition of topoisomerase I activity. MGB4 can impacts key cellular pathways, including inhibition oftranslation and alterations in sphingolipid and amino acid metabolism. MGB4 also reduces spermine and spermidine metabolism companied with Doxorubicin (HY-15142A). MGB4 can be used for the research of cancer, such as Prostate cancer .
Cat. No.: HY-156207
CAS No.: 261155-87-7
Synonyms: AdaGb3; Adamantyl Gb3; C2 Adamantanyl Ceramide Trihexoside (d18:1/2:0)
Target:
Research Areas:
C2 Adamantanyl globotriaosylceramide (d18:1/2:0) (AdaGb3), a water-soluble globotriaosylceramide analog, is a bioactive sphingolipid. C2 Adamantanyl globotriaosylceramide (d18:1/2:0) reverses MDR1-MDCK cell drug resistance. C2 Adamantanyl globotriaosylceramide (d18:1/2:0) has high affinity for verotoxin (VT) .
Cat. No.: HY-131701
CAS No.: 109785-20-8
Synonyms: C18 Lactosyl(β) Ceramide; Lactosyl Sphingosine; Lyso-Lactosylceramide (synthetic)
Target:
Research Areas:
Lactosyl-C18-sphingosine (C18 Lactosyl(β) Ceramide; Lactosyl Sphingosine) is a bioactive sphingolipid that is a form of lactosylceramide but lacks the fatty acyl group. Lysolactosylceramide (1-50 μM) reduces the viability of human neutrophils in a concentration-dependent manner. Unlike lactosylceramide, Lactosyl-C18-sphingosine has no effect on protein synthesis and cell proliferation in cardiomyocytes. Lactosyl-C18-sphingosine is a lysoganglioside GM3.
Cat. No.: HY-E70023
CAS No.: 170347-55-4
Target:
Research Areas:
Sphingolipid ceramide N-deacylase (SCDase) cleaves the N-acyl linkage between fatty acids and sphingosine bases in various glycosphingolipids. Sphingolipid ceramide N-deacylase catalyzes glycosphingolipids to lysoglycosphingolipids .
Cat. No.: HY-N15811
CAS No.: 497863-25-9
Category:
Target:
Cat. No.: HY-N15961
CAS No.: 2260670-20-8
Category:
Target:
Cat. No.: HY-N15958
CAS No.: 2342575-04-4
Target:
Research Areas:
Photoclick Sphingosine-1-Phosphate is a clickable sphingolipid that can be used in click chemistry reactions.
Cat. No.: HY-N15850
CAS No.: 147523-43-1
Category:
Target:
Cat. No.: HY-W741062
CAS No.: 26048-10-2
Synonyms: iso-C17:0; Isoheptadecasphinganine; 15-Methylhexadecasphinganine
Sphinganine (d16:0 branched) is an iso-branched sphingolipid. It has been found as a component of ceramide-containing phospholipids in bacteria.
Cat. No.: HY-154921A
Synonyms: LacCer (porcine RBC)
Target:
Research Areas:
Lactosylceramide (LacCer) (porcine RBC) is an endogenous bioactive sphingolipid. Lactosylceramide (porcine RBC) plays a pivotal role in mediating innate immune functions .
Cat. No.: HY-164267
CAS No.: 121999-55-1
Synonyms: SM (d18:1/14:0)
Target:
Research Areas:
Sphingomyelin (d18:1,C14:0), a major sphingolipid in mammalian cells, increases membrane molecular order .
Cat. No.: HY-164263
CAS No.: 21830-28-4
Synonyms: NAPS
N-Acetylphytosphingosine (NAPS) is a sphingolipid derivative. N-Acetylphytosphingosine induces mitochondria-dependent Apoptosis by activating Bak. N-Acetylphytosphingosine has antitumor activity .
Cat. No.: HY-168764
CAS No.: 34324-89-5
Target:
Research Areas:
C16 Galactosylceramide is a sphingolipid compound. C16 Galactosylceramide participates in the physiological processes of lipid metabolism and immune regulation in cells. C16 Galactosylceramide can be used in the study of diabetes .
Cat. No.: HY-176115
Synonyms: Sphing-14Z-enine
Target:
Research Areas:
Sphingosine (d18:1(14Z)) is an atypical sphingolipid that has a cis double bond at the 14-15 position. Sphingosine is a negative regulator of cell proliferation and can promote apoptosis .
Cat. No.: HY-113116S
CAS No.: 2315262-23-6
Butylate is a compound involved in platelet research. Platelet activation can cause autophagy, which is partly mediated by the AMPK-MTOR pathway and is related to sphingolipid metabolism. Butylate mentioned in the study may be a tool or control substance for studying related metabolic processes.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
