771 Results for "

Pc

" in MedChemExpress (MCE) Product Catalog:
Products (771)

771 Results for "Pc" in MCE Product Catalog:

Cat. No.: HY-N1353R
CAS No.: 569-92-6
Rhamnocitrin (Standard) is the analytical standard of Rhamnocitrin. This product is intended for research and analytical applications. Rhamnocitrin is an anti-inflammatory and antioxidant agent that targets STIM-1, NFATc3 and MAPK pathways and can scavenge DPPH (IC50=28.38 mM). Rhamnocitrin selectively inhibits oxidative stress and inflammatory responses in vascular endothelial cells and neurons. Rhamnocitrin up-regulates miR-185 to inhibit STIM-1-mediated store-operated calcium entry (SOCE), thereby blocking NFATc3 nuclear translocation and downstream inflammatory factor expression, while inducing heme oxygenase HO-1 expression and regulating the ERK/p38 MAPK pathway, inhibiting antioxidant and pro-inflammatory cytokines (such as IL-6, IL-8) and adhesion molecules (such as ICAM-1, VCAM-1). Rhamnocitrin can be used in the study of endothelial-related inflammatory diseases (such as sepsis, acute lung injury, atherosclerosis) and neuroprotection (such as oxidative damage of PC12 cells) .
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Cat. No.: HY-P7617
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ATG3; HApg3; Prev. APG3L; ATG3 Autophagy Related 3 Homolog (S. Cerevisiae); Pc3-96; APG3 Autophagy 3-Like (S. Cerevisiae); Ubiquitin-Like-Conjugating Enzyme ATG3; ATG3 Autophagy Related 3 Homolog; Autophagy-Related Protein 3; APG3 Autophagy 3-Like; DKFZp5
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P700956
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ENPP1; Nucleotide Diphosphatase; Prev. PDNP1; NPPase; Prev. M6S1; Membrane Component, Chromosome 6, Surface Marker 1; Prev. NPPS; Membrane Component Chromosome 6 Surface Marker 1; Pc-1; Plasma-Cell Membrane Glycoprotein 1; PcA1; Alkaline Phosphodiesterase
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P790076
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PRDX6; PRX; Peroxiredoxin 6; P29; AiPLA2; Red Blood Cells Page Spot 12; NSGPx; Lyso-Pc Acyltransferase 5; AOP2; LPc Acyltransferase 5; Acidic Calcium-Independent Phospholipase A2; Antioxidant Protein 2; Lysophosphatidylcholine Acyltransferase 5; Liver 2D
Species:  
Mouse
Source:  
E. coli
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Cat. No.: HY-162812
H3R antagonist 4 (compound 11L) was a dual inhibitor of cholinesterase and histamine receptor (H3R), with corresponding IC50 of 7.04 μM (eeAChE), 9.73 μM (hAChE)(reversible) and 1.09 nM (H3R) , respectively. H3R antagonist 4 inhibited the aggregation of Aβ1-42 induced by itself and Cu 2+ (95.48% and 88.63%) , and degraded the Aβ1-42 fibrils induced by itself and Cu 2+ (80.16% and 89.30%) . H3R antagonist 4 chelate biometals such as Cu 2+, Zn 2+, Al 3+, and Fe 2+. H3R antagonist 4 significantly reduced tau protein hyperphosphorylation induced by Aβ1-42 and inhibited RSL-3-induced apoptosis and ferroptosis in PC12 cells. H3R antagonist 4 had the best blood-brain barrier permeability and intestinal absorption in hCMEC/D3 and hPepT1-MDCK cells.H3R antagonist 4 ameliorates learning and memory impairment in a mouse model of Alzheimer's disease induced by scopolamine (HY-N0296) .
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Cat. No.: HY-P812030
Synonyms: MED27; Mediator Complex Subunit 27; CRSP34; TRAP37; CRSP8; MED3; Cofactor Required For Sp1 Transcriptional Activation, Subunit 8, 34kDa; Mediator Of RNA Polymerase II Transcription Subunit 27; Transcriptional Coactivator CRSP34; P37 TRAP/SMCC/Pc2 Subunit; CRSP Complex Subunit 8; Cofactor Required For Sp1 Transcriptional Activation Subunit 8; Epididymis Secretory Sperm Binding Protein; NEDSCAC; CRAP34

Host:  

Mouse

Application:  

WB

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P85902
Synonyms: CK 16; CK-16; CK16; Cytokeratin 16; CytokeRatin-16; CytokeRatin16; FNEPPK; Focal non epidermolytic palmoplantar keRatoderma; K 16; K16; K1C16_HUMAN; K1CP; KeRatin 1 type I; KeRatin 16; KeRatin; KeRatin type I cytoskeletal 16; KeRatin-16; KeRatin16; KRT 16; Krt16; KRT16A; NEPPK; Pc1; type I cytoskeletal 16

Host:  

Mouse

Application:  

IHC-P, WB, ICC/IF, ELISA

Reactivity:  

Human

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Cat. No.: HY-P812030A
Synonyms: MED27; Mediator Complex Subunit 27; CRSP34; TRAP37; CRSP8; MED3; Cofactor Required For Sp1 Transcriptional Activation, Subunit 8, 34kDa; Mediator Of RNA Polymerase II Transcription Subunit 27; Transcriptional Coactivator CRSP34; P37 TRAP/SMCC/Pc2 Subunit; CRSP Complex Subunit 8; Cofactor Required For Sp1 Transcriptional Activation Subunit 8; Epididymis Secretory Sperm Binding Protein; NEDSCAC; CRAP34

Host:  

Mouse

Application:  

WB

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P86960
Synonyms: Activator-recruited cofactor 36 kDa component antibody; ARC36 antibody; DRIP36 antibody; FLJ10956 antibody; HSPc126 antibody; med4 antibody; MED4_HUMAN antibody; Mediator complex subunit 4 antibody; Mediator of RNA polymerase II transcription subunit 4 antibody; Mediator of RNA polymerase II transcription, subunit 4 homolog antibody; Activator-recruited cofactor 36 kDa component antibody; ARC36 antibody; DRIP36 antibody; FLJ10956 antibody; HSPc126 antibody; med4 antibody; MED4_HUMAN antibody; Mediator complex subunit 4 antibody; Mediator of RNA polymerase II transcription subunit 4 antibody; Mediator of RNA polymerase II transcription, subunit 4 homolog antibody; OTTHUMP00000018390 antibody; OTTHUMP00000018391 antibody; OTTHUMP00000018392 antibody; RP11-90M2.2 antibody; TRAP/SMCC/Pc2 subunit p36 subunit antibody; TRAP36 antibody; VDR; IP : antibody; Vitamin D3 receptor-interacting protein complex 36 kDa component antibody;

Host:  

Rabbit

Application:  

WB, ICC/IF, IHC-P

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P85613
Synonyms: Dmel\CG6376; Dmel_CG6376; drosE2F1; E; Sev-CycE; 3A; E; var; 3-93E; E2-promoter binding facto; E2F 1; E2F transcription factor 1; E2F-1; E2f-PA; E2f-PB; E2f-Pc; E2F1; E2f1 E2F transcription factor 1; E2F1_HUMAN; Evar; 3; 164; KIAA4009; l; 3; 07172; l; 3; j3B1; l; 3; j3C2; l; 3; rM729; mKIAA4009; OTTHUMP00000030661; PBR3; PRB binding protein E2F 1; PRB-binding protein E2F-1; RBAP 1; RBAP-1; RBAP1; RBBP-3; RBBP3; RBP 3; RBP3; Retinoblastoma-associated protein 1; Retinoblastoma-binding protein 3; Transcription factor E2F1.

Host:  

Mouse

Application:  

WB, ICC/IF, IP

Reactivity:  

Human, Rat

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Cat. No.: HY-P85616
Synonyms: Dmel\CG6376; Dmel_CG6376; drosE2F1; E; Sev-CycE; 3A; E; var; 3-93E; E2-promoter binding facto; E2F 1; E2F transcription factor 1; E2F-1; E2f-PA; E2f-PB; E2f-Pc; E2F1; E2f1 E2F transcription factor 1; E2F1_HUMAN; Evar; 3; 164; KIAA4009; l; 3; 07172; l; 3; j3B1; l; 3; j3C2; l; 3; rM729; mKIAA4009; OTTHUMP00000030661; PBR3; PRB binding protein E2F 1; PRB-binding protein E2F-1; RBAP 1; RBAP-1; RBAP1; RBBP-3; RBBP3; RBP 3; RBP3; Retinoblastoma-associated protein 1; Retinoblastoma-binding protein 3; Transcription factor E2F1.

Host:  

Mouse

Application:  

WB, ICC/IF, IP

Reactivity:  

Human, Mouse, Rat

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