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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
93 Results for "
blight
" in MedChemExpress (MCE) Product Catalog:
Products (93)
93 Results for "blight" in MCE Product Catalog:
Category:
Target:
Art. -Nr.: HY-178050
Target:
Forschungsgebiete:
SDH-IN-30 (Compound 7m) is a Succinate dehydrogenase (SDH) inhibitor with an IC50 of 0.34 μM. SDH-IN-30 has potent antifungal activities against Rhizoctonia solani and Sclerotinia sclerotiorum with EC50 s of 0.004 and 0.028 μg/mL. SDH-IN-30 also has remarkable protective and curative efficacies against R. solani and significantly inhibits S. sclerotiorum growth on oilseed rape leaves by damaging the fungal cell structure. SDH-IN-30 can be used for fungal infections like rice sheath blight (RSB) and sclerotinia stem rot (SSR) research .
Art. -Nr.: HY-178988
Antibacterial agent 299 (Compound P5) is a highly effective antibacterial agent against Xanthomonas oryzae pv. oryzae (Xoo), with an EC₅₀ value of 6.9 μg/mL. Antibacterial agent 299 integrates into bacterial membranes, disrupts membrane structure, inhibits biofilm formation, and thus exerts antibacterial effects. Antibacterial agent 299 also shows inhibitory activity against Xanthomonas oryzae pv. oryzicola (Xoc) (EC₅₀ = 32.5 ± 3.0 μg/mL), but its activity against Xanthomonas axonopodis pv. citri (Xac) is weaker. Antibacterial agent 299 demonstrated excellent control efficacy in a rice bacterial blight (BLB) model. Antibacterial agent 299 can be used for BLB research .
Art. -Nr.: HY-W017611S
CAS. Nr.: 352431-21-1
Art. -Nr.: HY-W583753
CAS. Nr.: 13492-26-7
Dipotassium phosphite is a phosphite salt and is an antibacterial agent. Dipotassium phosphite directly and indirectly affects development of Phytophthora infestans.Dipotassium phosphite reduces late blight severity in field-grown tomato plants and increases productivity of field-grown tomato plants. Dipotassium phosphite can be used for the research of late blight .
Art. -Nr.: HY-185574
CAS. Nr.: 2757172-25-9
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Enpyracymid is a succinate dehydrogenase inhibitor (SDHI) fungicide with fungicidal activity against fungal. It can be used in studies related to Fusarium head blight (FHB) .
Art. -Nr.: HY-W715370
CAS. Nr.: 915410-70-7
Pyrametostrobin is a strobilurin fungicide used to protect crops from fungal infection. Pyrametostrobin can be applied to research related to cucumber powdery mildew, powdery mildew, rust, downy mildew and blight .
Art. -Nr.: HY-N5197A
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Art. -Nr.: HY-183966
Antibacterial agent 348 is an antimicrobial agent containing piperazine-isopropanolamine bifunctional groups. Antibacterial agent 348 suppresses virulence factor expression in plant pathogens. Antibacterial agent 348 compromises bacterial membrane integrity, leading to cytoplasmic leakage. Antibacterial agent 348 inhibits cellular proliferation of plant pathogens, diminishes colonization and infectivity of plant pathogens in host plants. Antibacterial agent 348 can be used for the research of rice bacterial leaf blight, pepper phytophthora blight .
Art. -Nr.: HY-184334
FtsZ-IN-15 is an inhibitor targeting the FtsZ protein of Xanthomonas oryzae pv. oryzae (Xoo) and a cell division inhibitor. FtsZ-IN-15 specifically binds to key residues of XooFtsZ, inhibits its GTPase activity and disrupts its polymerization. FtsZ-IN-15 induces cell elongation of Xanthomonas oryzae pv. oryzae and exhibits significant antibacterial activity against this strain. FtsZ-IN-15 shows good control efficacy against rice bacterial blight and can be used in relevant research on rice bacterial blight .
Art. -Nr.: HY-W281071
CAS. Nr.: 67365-93-9
Antifungal agent 150 is an antifungal agent with activity against phytopathogenic fungi and in planta lesion suppression. Antifungal agent 150 inhibits ergosterol biosynthesis via targeted enzyme interaction. Antifungal agent 150 can be used for the research of plant diseases caused by Rhizoctonia solani, including banded leaf and sheath blight of maize .
Art. -Nr.: HY-183475
CAS. Nr.: 37209-50-0
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Art. -Nr.: HY-184421
Antibacterial agent 354 is a bactericide targeting the LolCDE complex, with broad-spectrum activity against phytopathogens. Antibacterial agent 354 regulates gene expression, disrupts lipoprotein transport and inhibits bacterial division. Antibacterial agent 354 prevents and controls rice bacterial blight and kiwifruit canker in plant models, and is used in relevant studies .
Art. -Nr.: HY-187992
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Forschungsgebiete:
SDH-IN-48 is a succinate dehydrogenase (SDH) inhibitor, with an IC50 of 0.056 μM against porcine SDH. SDH-IN-48 binds to the SDH active pocket through multiple non-covalent interactions. SDH-IN-48 can be used in related research on rice sheath blight disease .
Art. -Nr.: HY-162898
CAS. Nr.: 2983120-29-0
Anti-virulence factor-IN-1 (Compound 4S) is a bacterial virulence factor inhibitor by interfering with the bacterial infection process. Anti-virulence factor-IN-1 exhibits an antibacterial activity against Xoo in vitro with an EC50 value of 0.28 µg/mL. Anti-virulence factor-IN-1 can be used to effectively manage rice bacterial leaf blight in vivo. Anti-virulence factor-IN-1 is promising for research of plant bacterial disease .
Art. -Nr.: HY-189346
Myosin I-IN-1 is an Antifungal agent and Myosin I inhibitor with a Kd of 0.14 μM for FgMyoI. Myosin I-IN-1 inhibits mycelial growth, sporulation, spore germination, and Deoxynivalenol (HY-N6684) biosynthesis. Myosin I-IN-1 disrupts cell wall and cell membrane integrity and induces hyphal morphological changes. Myosin I-IN-1 exhibits broad-spectrum antifungal activity against plant pathogenic fungi. Myosin I-IN-1 shows protective efficacy against Fusarium head blight in wheat and maize. Myosin I-IN-1 can be used for research on Fusarium head blight .
Art. -Nr.: HY-187991
FtsZ-IN-16 is a curcumin derivative and also an inhibitor of XooFtsZ, with an EC50 of 3.74 μg/mL against Xoo. FtsZ-IN-16 targets the FtsZ residues LEU71, GLY74, GLY110 and THR111 of Xanthomonas oryzae pv. oryzae, thereby blocking GTPase (GTPase) activity and polymerization. FtsZ-IN-16 can be used in studies related to rice bacterial blight .
Art. -Nr.: HY-175647
Myosin-5-IN-2 (Compound G19) is a Myosin-5 inhibitor. Myosin-5-IN-2 has an antifungal activity against Fusarium graminearum (Fg), Botrytis cinerea and Rhizoctonia solani with an EC50 s of 0.326 μg/mL for Fg. Myosin-5-IN-2 has effective protective and curative control efficiency for wheat leaves. Myosin-5-IN-2 severely damages the surface integrity of mycelial cells and induces cytoplasmic leakage. Myosin-5-IN-2 can be used for fungal infections like fusarium head blight (FHB) research .
Art. -Nr.: HY-189073
Forschungsgebiete:
Antifungal agent 175 is a potent antifungal agent with an EC50 of 1.8 μg/mL against R. solani. Antifungal agent 175 Z17 exerts its effects primarily by disrupting the cell membranes of pathogenic fungi to trigger lipid peroxidation and oxidative stress, inhibiting pyruvate kinase (PK) to interfere with energy metabolism, and binding to the cytochrome bc1 complex. Antifungal agent 175 can be used in research on rice sheath blight .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
