Antifungal agent 175

Antifungal agent 175 (compound Z17) potently inhibits the mycelial growth of various phytopathogenic fungi, with the strongest activity against Rhizoctonia solani, with an EC₅₀ value of 1.8 μg/mL^[1].
Antifungal agent 175 (1.56-25 μg/mL; 24 h) potently and concentration-dependently inhibits sclerotial germination of Rhizoctonia solani^[1].
Antifungal agent 175 potently inhibits the mycelial growth of Rhizoctonia solani, Phomopsis sp., Sclerotinia sclerotiorum, Botrytis cinerea, Phytophthora capsica, Valsa mali, and Botryosphaeria dothidea, with EC₅₀ values ranging from 1.8 μg/mL to 14.9 μg/mL^[1].
Antifungal agent 175 (25-50 μg/mL) disrupts the membrane integrity of Rhizoctonia solani mycelia and induces intracellular reactive oxygen species accumulation in a concentration-dependent manner^[1].
Antifungal agent 175 (3.125-25 μg/mL) reduces the pyruvate content and pyruvate kinase activity in Rhizoctonia solani in a dose-dependent manner, indicating that it interferes with cellular energy metabolism^[1].
Antifungal agent 175 forms an extensive interaction network with the cytochrome bc₁ complex and creates a stable complex^[1].
Antifungal agent 175 (50-200 μg/mL; 24 h seed soaking followed by 7 days of incubation) exerts no significant effect on seed germination, root length, or shoot length of Oryza sativa L.^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.