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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
203 Results for "
IL-8
" in MedChemExpress (MCE) Product Catalog:
Products (203)
203 Results for "IL-8" in MCE Product Catalog:
Cat. No.: HY-179009
Research Areas:
NOD2 agonist 4 (Compound 12b) is a potent NOD2 agonist with an EC50 of 44.1 nM. NOD2 agonist 4 induces cytokine production (MCP-1, IL-6 and IL-8) in peripheral blood mononuclear cells (PBMCs), both alone and in combination with Lipopolysaccharide (LPS) (HY-D1056). NOD2 agonist 4 can be used for the studies of NOD2-targeted immunomodulator or vaccine adjuvant .
Cat. No.: HY-174729
Target:
Research Areas:
Human IL8 mRNA encodes the human interleukin 8 (IL8) protein, a member of the CXC chemokine family. IL8 is a major mediator of the inflammatory response. It also functions as a chemotactic factor by guiding the neutrophils to the site of infection.
Cat. No.: HY-118316
CAS No.: 899758-61-3
Target:
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GSK223 is a quinazolinone NOD1 pathway inhibitor with potential anti-inflammatory activity. GSK223 can selectively inhibit IL-8 release under iE-DAP stimulation without affecting IL-8 secretion caused by TNF receptor, TLR2 or NOD2 agonists. GSK223 does not directly inhibit RIP2 kinase activity.
Target:
Cat. No.: HY-124613
CAS No.: 200417-97-6
Target:
Research Areas:
Pyrazinib is a inhibitor of angiogenesis and metabolism of oesophageal adenocarcinoma (oac) radioresistance, inhibiting the secretion of Il-6, Il-4, Il-8 and Il-13 cytokines from in oac radioresistant cells. Pyrazinib inhibits blood vessel development in zebrafish .
Cat. No.: HY-B0348R
CAS No.: 88678-31-3
Synonyms: Piritetrate (Standard); M-732 (Standard)
Target:
Research Areas:
Liranaftate (Standard) is the analytical standard of Liranaftate. This product is intended for research and analytical applications. Liranaftate (Piritetrate) is a squalene epoxidase inhibitor with anti-fungicidal activities. Liranaftate can be used for the research of dermatophytes. Liranaftate also suppresses fungal element-promoted production of IL-8 and experimental inflammation .
Cat. No.: HY-P10692
CAS No.: 135154-02-8
Target:
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Cat. No.: HY-W342458
CAS No.: 5534-13-4
Cat. No.: HY-111214
CAS No.: 880546-17-8
Research Areas:
K-14585 is a peptide competitive PAR2 antagonist. K-14585 inhibits PAR2-dependent IL-8 production, NF-κB phosphorylation, and p38 signaling. K-14585 reduces SLIGKV (PAR2 agonist peptide)-induced Ca 2+ mobilisation in primary human keratinocytes .
Cat. No.: HY-18263
CAS No.: 688763-65-7
Synonyms: SB-656933 hydrochloride
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Elubrixin (SB-656933) hydrochloride is a potent, selective, competitive, reversible and orally active CXCR2 antagonist and an IL-8 receptor antagonist. Elubrixin hydrochloride inhibits neutrophil CD11b upregulation (IC50 of 260.7 nM) and shape change (IC50 of 310.5 nM). Elubrixin hydrochloride has the potential for inflammatory diseases research, such as inflammatory bowel disease and airway inflammation .
Cat. No.: HY-174727
Target:
Research Areas:
Human CXCR2 mRNA encodes the human C-X-C motif chemokine receptor 2 (CXCR2) protein, a member of the G-protein-coupled receptor family. CXCR2 is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum-dependent melanoma cell growth.
Cat. No.: HY-172660
Target:
Research Areas:
36R-D481 is a competitive and orthosteric antagonist of IL-36R, effectively inhibiting IL-36 signaling. 36R-D481 can inhibit IL-36α and IL-36γ but not IL-36β induced IL-8 release .
Cat. No.: HY-N0314R
CAS No.: 28978-02-1
Cat. No.: HY-P3259
CAS No.: 2093408-03-6
Research Areas:
Cat. No.: HY-N6685S1
CAS No.: 1217476-81-7
Synonyms: 3-AcDON-13C17; 3-ADON-13C17
Cat. No.: HY-19717S
Synonyms: S-[(1E)-1,2-Dichloroethenyl]-L-cysteine-13C3,15N
Cat. No.: HY-N6927R
CAS No.: 64657-21-2
Synonyms: Coleonol B (Standard)
Cat. No.: HY-128423AS
Synonyms: Acetylisovaleryltylosin-d9
Cat. No.: HY-N12905
CAS No.: 491600-94-3
Category:
Target:
Cat. No.: HY-N6685R
CAS No.: 50722-38-8
Synonyms: 3-AcDON (Standard); 3-ADON (Standard)
Category:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
