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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
994 Results for "
sequence
" in MedChemExpress (MCE) Product Catalog:
Products (994)
994 Results for "sequence" in MCE Product Catalog:
Cat. No.: HY-W008806
CAS No.: 143537-62-6
Synonyms: OHHL; N-(3-Oxohexanoyl)homoserine lactone
Target:
Research Areas:
N-(3-Oxohexanoyl)-L-homoserine lactone (OHHL; N-(3-Oxohexanoyl)homoserine lactone) is a specific agonist of LuxR-type transcription factor CarR with a Kd of 1.8 μM. N-(3-Oxohexanoyl)-L-homoserine lactone activates CarR by inducing protein multimerization, promoting its binding to target DNA sequences in the carR-carA intergenic region, thereby upregulating the transcription of carbapenem biosynthesis genes. N-(3-Oxohexanoyl)-L-homoserine lactone acts as a quorum sensing signal molecule, enabling bacteria to coordinate the production of carbapenem antibiotics in a cell density-dependent manner. N-(3-Oxohexanoyl)-L-homoserine lactone is used to study bacterial quorum sensing mechanisms, especially the secondary metabolism and virulence factor regulatory pathways of Erwinia carotovora and Yersinia enterocolitica .
Cat. No.: HY-P71639
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: C1QTNF3; C1q And Tumor Necrosis Factor Related Protein 3; C1q And TNF Related 3; Secretory Protein CORS26; CTRP3; 2310005P21Rik; Cors-26; Cartonectin; Corcs; CORS26; Cors; Collagenous Repeat-Containing sequence Of 26-KDa; Complement C1q Tumor Necrosis Fac
Species:
Mouse
Source:
E. coli
Cat. No.: HY-P87378
Synonyms: 1810017N16Rik antibody; Chromosome 3p21.1 gene sequence antibody; HUMAGCGB antibody; huOTT3 antibody; One twenty two protein 3 antibody; One-twenty two protein 3 antibody; OTT3 antibody; Putative RNA binding protein 15B antibody; Putative RNA-binding protein 15B antibody; RB15B_HUMAN antibody
Cat. No.: HY-P811765
Synonyms: FACT80, SSRP1, FACT complex subunit SSRP1, Chromatin-specific transcription elongation factor 80 kDa subunit, Facilitates chromatin transcription complex 80 kDa subunit, Facilitates chromatin transcription complex subunit SSRP1, Recombination signal sequence recognition protein 1, Structure-specific recognition protein 1, T160, FACT 80 kDa subunit, FACTp80, hSSRP1
Cat. No.: HY-137697
CAS No.: 66004-77-1
Cat. No.: HY-137697B
CAS No.: 93939-77-6
Research Areas:
ddCTP trilithium is a type of chain-terminating deoxynucleotide. ddCTP trilithium can be incorporated into the extension primer chain that lacks the 3'-hydroxyl group, thereby terminating primer extension, viral genome replication, and DNA synthesis. ddCTP trilithium can distinguish almost identical RNA through distinguishable extension products in primer extension inhibition experiments. ddCTP trilithium is the active metabolite of Zalcitabine (HY-17392), which can competitively inhibit HIV reverse transcriptase, terminate the synthesis of viral DNA chains, and thereby inhibit HIV replication .
Cat. No.: HY-137697D
Purity: ≥98.0%
Research Areas:
ddCTP trilithium solution (100 mM) is a chain-terminating dideoxynucleotide. ddCTP trilithium is a type of chain-terminating deoxynucleotide. ddCTP trilithium can be incorporated into the extension primer chain that lacks the 3'-hydroxyl group, thereby terminating primer extension, viral genome replication, and DNA synthesis. ddCTP trilithium can distinguish almost identical RNA through distinguishable extension products in primer extension inhibition experiments. ddCTP trilithium is the active metabolite of Zalcitabine (HY-17392), which can competitively inhibit HIV reverse transcriptase, terminate the synthesis of viral DNA chains, and thereby inhibit HIV replication .
Cat. No.: HY-D1725
Cat. No.: HY-153805
CAS No.: 1373391-77-5
Target:
Research Areas:
Z-NCTS is a small molecule that binds to mismatched RNA, recognizes the 5'-r (XGG)-3'/5'-r (XGG)-3' sequence, and acts as an RNA molecular glue. Z-NCTS induces the formation of tertiary structures in ribozymes and activates their RNA cleavage activity. As an RNA molecular glue, Z-NCTS enables small molecule-based strategies for regulating RNA structure and function. Z-NCTS binds to d (CGG)/d (CGG) double-stranded DNA, recognizes four guanine bases via hydrogen bonding, and stabilizes the double-stranded DNA. Z-NCTS binds to r (GGG)/r (GGG) double-stranded RNA and enhances the thermodynamic stability of the RNA duplex. Z-NCTS acts as a translation inhibitor by inducing the formation of stable hairpin structures in the 5'-UTR region of engineered mRNA, thereby blocking ribosomal access to the binding site .
Cat. No.: HY-15594
CAS No.: 942936-75-6
Target:
Research Areas:
Phen-DC3 is a bisquinolinium G-quadruplex (G4) ligand. Phen-DC3 selectively binds to and stabilizes the hybrid quadruplex-duplex hybrid (QDH) derived from the PIM1 promoter. Phen-DC3 also binds to the c-myc promoter Pu24T G4 via extensive π-stacking, and induces polymerase stalling at α-synuclein DNA and RNA G4 sequences. Phen-DC3 Trifluoromethanesulfonate (HY-15594A) downregulates LPS (HY-D1056)-induced TNFRSF21, RIPK3 and p-MLKL in VECs, and ameliorates CLP-induced pulmonary vascular leakage in septic rats. Phen-DC3 can be used in studies related to neurodegenerative diseases and sepsis-associated vascular injury .
Cat. No.: HY-P5325
CAS No.: 505070-05-3
Target:
Research Areas:
Cat. No.: HY-P5325A
Target:
Research Areas:
Cat. No.: HY-P991959
Target:
Research Areas:
Cat. No.: HY-W004812
CAS No.: 161660-94-2
Synonyms: (1S,3S)-3-[(tert-Butoxycarbonyl)amino]cyclopentanecarboxylic acid
Target:
Research Areas:
BOC-(1R,3S)-3-aminocyclopentane carboxylic acid ((1S,3S)-3-[(tert-Butoxycarbonyl)amino]cyclopentanecarboxylic acid) is a conformationally constrained peptide building block and a key component of SARS-CoV-2 main protease (Mpro) inhibitors. When incorporated into macrocyclic peptides, BOC-(1R,3S)-3-aminocyclopentane carboxylic acid not only helps generate high-affinity Mpro inhibitors by preorganizing the secondary structure of peptides, but also exerts sequence-dependent functional inhibition on the hydrolytic activity of Mpro. BOC-(1R,3S)-3-aminocyclopentane carboxylic is widely used in COVID-19-related research .
Cat. No.: HY-W040129R
CAS No.: 7059-24-7
Category:
Cat. No.: HY-P71648
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: C1QTNF3; C1q And Tumor Necrosis Factor Related Protein 3; C1q And TNF Related 3; Secretory Protein CORS26; CTRP3; 2310005P21Rik; Cors-26; Cartonectin; Corcs; CORS26; Cors; Collagenous Repeat-Containing sequence Of 26-KDa; Complement C1q Tumor Necrosis Fac
Species:
Human
Source:
E. coli
Cat. No.: HY-P72018
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: KLRK1; CD314; Prev. D12S2489E; Killer Cell Lectin-Like Receptor Subfamily K, Member 1; NKG2D; NKG2-D-Activating NK Receptor; NKG2-D Type II Integral Membrane Protein; DNA Segment On Chromosome 12 (Unique) 2489 Expressed sequence; NK Cell Receptor D; Kille
Species:
Human
Source:
HEK293
Cat. No.: HY-P72504
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: KLRK1; CD314; Prev. D12S2489E; Killer Cell Lectin-Like Receptor Subfamily K, Member 1; NKG2D; NKG2-D-Activating NK Receptor; NKG2-D Type II Integral Membrane Protein; DNA Segment On Chromosome 12 (Unique) 2489 Expressed sequence; NK Cell Receptor D; Kille
Species:
Cynomolgus
Source:
HEK293
Cat. No.: HY-P73319
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: KLRK1; CD314; Prev. D12S2489E; Killer Cell Lectin-Like Receptor Subfamily K, Member 1; NKG2D; NKG2-D-Activating NK Receptor; NKG2-D Type II Integral Membrane Protein; DNA Segment On Chromosome 12 (Unique) 2489 Expressed sequence; NK Cell Receptor D; Kille
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P75940
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: KLRK1; CD314; Prev. D12S2489E; Killer Cell Lectin-Like Receptor Subfamily K, Member 1; NKG2D; NKG2-D-Activating NK Receptor; NKG2-D Type II Integral Membrane Protein; DNA Segment On Chromosome 12 (Unique) 2489 Expressed sequence; NK Cell Receptor D; Kille
Species:
Rhesus Macaque
Source:
Sf9 insect cells
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
