1. Cell Cycle/DNA Damage
  2. DNA/RNA Synthesis
  3. Phen-DC3

Phen-DC3 

Cat. No.: HY-15594
Handling Instructions

Phen-DC3 is a G-quadruplex (G4) specific ligand which can inhibit FANCJ and DinG helicases with IC50s of 65±6 and 50±10 nM, respectively.

For research use only. We do not sell to patients.

Phen-DC3 Chemical Structure

Phen-DC3 Chemical Structure

CAS No. : 942936-75-6

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Description

Phen-DC3 is a G-quadruplex (G4) specific ligand which can inhibit FANCJ and DinG helicases with IC50s of 65±6 and 50±10 nM, respectively.

IC50 & Target

IC50: 65±6 nM (G4 substrate, FANCJ helicase), 50±10 nM (G4 substrate, DinG helicases)[1].

Molecular Weight

550.61

Formula

C₃₄H₂₆N₆O₂

CAS No.

942936-75-6

SMILES

C[N+]1=C2C=CC=CC2=CC(NC(C3=CC=C4C=CC5=CC=C(C(NC6=C[N+](C)=C7C=CC=CC7=C6)=O)N=C5C4=N3)=O)=C1

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

DMSO : ≥ 34 mg/mL (61.75 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8162 mL 9.0808 mL 18.1617 mL
5 mM 0.3632 mL 1.8162 mL 3.6323 mL
10 mM 0.1816 mL 0.9081 mL 1.8162 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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This equation is commonly abbreviated as: C1V1 = C2V2

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Phen-DC3
Cat. No.:
HY-15594
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