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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
91 Results for "
DHA
" in MedChemExpress (MCE) Product Catalog:
Products (91)
91 Results for "DHA" in MCE Product Catalog:
Cat. No.: HY-116115
CAS No.: 1233715-33-7
Synonyms: 17-Oxo-DPA; 17-Oxo-7(Z),10(Z),13(Z),15(E),19(Z)-DPA
Research Areas:
17-Oxo-7(Z),10(Z),13(Z),15(E),19(Z)-docosapentaenoic acid (17-Oxo-DPA; 17-Oxo-7(Z),10(Z),13(Z),15(E),19(Z)-DPA) is an electrophilic oxo-derivative (EFOX) of the docosahexaenoic acid (DHA) (HY-B2167). 17-Oxo-7(Z),10(Z),13(Z),15(E),19(Z)-docosapentaenoic acid is generated during inflammation by COX-2-catalyzed mechanism in activated macrophages. 17-Oxo-7(Z),10(Z),13(Z),15(E),19(Z)-docosapentaenoic acid acts as an agonist for PPARγ and a modulator for NF-κB signaling pathway, inhibits the production of pro-inflammatory cytokines and nitric oxide, and exhibits anti-inflammatory efficacy .
Cat. No.: HY-N20754
DHA-free EPA oil is an EPA-enriched oil (HY-B0660) that does not contain DHA (HY-B2167). Eicosapentaenoic Acid (EPA) is an orally active ω-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA). Eicosapentaenoic Acid promotes DNA demethylation that re-expresses the tumor suppressor gene CCAAT/enhancer-binding protein δ (C/EBPδ). Eicosapentaenoic Acid activates the RAS/ERK/C/EBPβ pathway in U937 leukemia cells through demethylation of the H-RAS intron 1 CpG island. Eicosapentaenoic Acid promotes relaxation and vasodilation of vascular smooth muscle cells.
Cat. No.: HY-W741686
CAS No.: 99296-82-9
Synonyms: 1-Oleoyl-2-docosahexaenoyl-sn-glycero-3-phosphocholine
Target:
Research Areas:
1-Oleoyl-2-DHA-PC (1-Oleoyl-2-docosahexaenoyl-sn-glycero-3-phosphocholine) is a 5-lipoxygenase inhibitor with an ID50 of 4.0 μM. It inhibits the conversion of arachidonic acid (HY-109590) to 5-HETE in a non-competitive manner and maintains membrane fluidity under high hydrostatic pressure through conformational disorder conferred by multiple cis double bonds. 1-Oleoyl-2-DHA-PC is used in lipoxygenase-related research and membrane biophysics studies .
Cat. No.: HY-CE00355
CAS No.: 28465-45-4
Synonyms: DHA-Coenzyme A
Target:
Research Areas:
(4Z,7Z,10Z,13Z,16Z,19Z)-Docosahexaenoyl-CoA (DHA-Coenzyme A) is an unsaturated fatty acyl-CoA.
Cat. No.: HY-175071
CAS No.: 1639940-78-5
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(4S,11R)-DiHDoHE is a derivative of Dihydroxy-DHA .
Cat. No.: HY-101847R
CAS No.: 99584-96-0
Research Areas:
DBHDA (Standard) is the analytical standard of DBHDA (HY-101847). This product is intended for research and analytical applications. DBHDA is organic compound, which converts cysteine to dehydroalanine (DHA) .
Cat. No.: HY-101540R
CAS No.: 129024-87-9
Target:
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NMI 8739 (Standard) is the analytical standard of NMI 8739 (HY-101540). This product is intended for research and analytical applications. NMI 8739 is a dopamine D2 autoreceptor agonist, which is an amine conjugate of the DHA carrier and the neurotransmitter dopamine.
Cat. No.: HY-W192276
CAS No.: 20862-11-7
Synonyms: N-Desisopropylpropranolol
Target:
Research Areas:
Cardiovascular Disease Neurological Disease Endocrinology Cancer
(±)-Desisopropylpropranolol (N-Desisopropylpropranolol) is a metabolite of Propranolol (HY-B0573B). Propranolol is a nonselective β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with Kis of 1.8 nM and 0.8 nM, respectively. Propranolol inhibits [ 3H]-DHA binding to rat brain membrane preparation with an IC50 of 12 nM. Propranolol is used for the study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy .
Cat. No.: HY-FL0003
Synonyms: Lipoplus 20%
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ω-3-Fish oil medium and long chain fat emulsion is composed of fish oil, soybean oil and medium-chain triglycerides, and can be used as a nutritional supplement. ω-3-Fish oil medium and long chain fat emulsion contains high levels of DHA and EPA, which have anti-inflammatory effects and are essential for nervous system development. The ω-6:ω-3 PUFA ratio is closer to the ideal bioavailable ratio for humans, providing the body with necessary energy and essential fatty acids, while inhibiting inflammation and protecting liver function.
Cat. No.: HY-L043
2,028 compounds
Lipids are a diverse and ubiquitous group of compounds which have many key biological functions, such as acting as structural components of cell membranes, serving as energy storage sources and participating in signaling pathways. Several studies suggest that bioactive lipids have effects on the treatment of some mental illnesses and metabolic syndrome. For example, DHA and EPA are important for monoaminergic neurotransmission, brain development and synaptic functioning, and are also correlated with a reduced risk of cancer and cardiovascular disease in clinical and animal studies.
MCE supplies a unique collection of 2,028 lipid and lipid derivative related compounds including triglycerides, phospholipids, sphingolipids, steroids and their structural analogues or derivatives. MCE lipid compound library can be used for research in bioactive lipids, and high throughput screening (HTS) and high content screening (HCS).
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
