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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
91 Results for "
DHA
" in MedChemExpress (MCE) Product Catalog:
Products (91)
91 Results for "DHA" in MCE Product Catalog:
Cat. No.: HY-130288
CAS No.: 90780-53-3
Synonyms: (±)13-HDoHE; 13-hydroxy Docosahexaenoic acid; (±)13-HDoHE
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(±)13-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro. It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes. Fresh water hydra is shown to metabolize DHA to 13(R)-HDHA, presumably via the 11R-lipoxygenase activity. (±)13-HDHA is a potential marker of oxidative stress in brain and retina where DHA is an abundant polyunsaturated fatty acid.
Cat. No.: HY-W103225
CAS No.: 613-31-0
Dihydroanthracene (9,10-Dihydroanthracene) is a substrate for toluene dioxygenase (TDO) expressed by Pseudomonas putida UV4. Toluene dioxygenase (TDO) expressed by Pseudomonas putida UV4 catalyzes the benzylic monooxygenation of Dihydroanthracene to 9-hydroxy-9,10-DHA as the only product .
Synonyms: (±)20-HDoHE
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Cat. No.: HY-101541S
CAS No.: 2687960-96-7
Synonyms: Methyl docosahexaenoate-d5; all cis-DHA methyl ester-d5
Cat. No.: HY-107343R
CAS No.: 81926-94-5
Synonyms: Ethyl docosahexaenoate (Standard)
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Docosahexaenoic acid ethyl ester (Standard) is the analytical standard of Docosahexaenoic acid ethyl ester. This product is intended for research and analytical applications. Docosahexaenoic acid ethyl ester (Ethyl docosahexaenoate) is a 90% concentrated ethyl ester of docosahexaenoic acid manufactured from the microalgal oil. Docosahexaenoic acid ethyl ester enhances 6-hydroxydopamine-induced neuronal damage by induction of lipid peroxidation in mouse striatum. Docosahexaenoic acid (DHA) is a key component of the cell membrane, and its peroxidation is inducible due to the double-bond chemical structure. Docosahexaenoic acid has neuroprotective effects .
Cat. No.: HY-N16406
CAS No.: 41451-81-4
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Cat. No.: HY-139247
CAS No.: 2454246-25-2
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pNPS-DHA (Compound 19) is an orally active DHA-ethanolamide (DHEA) derivative that has antiallergic activity. pNPS-DHA inhibits IgE-dependent passive cutaneous anaphylaxis (PCA) reaction in mice. pNPS-DHA has anti-degranulating activity in RBL-2H3 mast cells with an IC50 of 15 μM .
Synonyms: DHA-5-HT
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Docosahexaenoyl serotonin (DHA-5-HT) is an endogenous n-3 fatty acid-serotonin conjugate. Docosahexaenoyl serotonin is an inhibitor of IL-17. Docosahexaenoyl serotonin has anti-inflammatory activity .
Cat. No.: HY-113777
CAS No.: 90780-46-4
Synonyms: 22-Hydroxy Docosahexaenoic acid; 22-OH DHA
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22-HDHA (22-Hydroxy Docosahexaenoic acid) is an oxidation product of docosahexaenoic acid. In vitro, it is formed upon incubation of rat liver microsomes with DHA and NADPH and also by the human cytochrome P450 (CYP) isoform CYP4F3B in BTI-TN-5B1-4 microsomes. Serum levels of 22-HDHA increase following dietary DHA supplementation in humans.
Cat. No.: HY-158594
CAS No.: 2692622-57-2
Synonyms: DHA-alkyne; FA 22:8
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Docosahexaenoic acid alkyne (DHA-alkyne) is an ω-alkyne derivative of Docosahexaenoic acid (HY-B2167). Docosahexaenoic acid alkyne can be used in cancer-related research .
Cat. No.: HY-134997
CAS No.: 845673-74-7
Synonyms: 4-oxo DHA
4-oxo Docosahexaenoic acid (4-oxo DHA) is a putative metabolite of Docosahexaenoic acid (HY-B2167) with antiproliferative and PPARγ agonist activity. It inhibits the growth of several triple negative breast cancer cell lines (MCF-10F, trMCF, bsMCF, MDA-MB-231, and BT549) at 50-100 μM, however it increased proliferation of MCF-7 cells. 4-oxo DHA binds covalently to PPARγ and activates gene transcription in luciferase reporter assays and in dendritic cells with EC50 values of approximately 8-16 μM.
Cat. No.: HY-139408
CAS No.: 1233715-28-0
Synonyms: 17-Oxo-DHA; 17-Oxo-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-DHA
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17-Oxo-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-docosahexaenoic acid (17-Oxo-DHA) is a metabolite of lipoxygenase-mediated oxidation of DHA. 17-Oxo-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-docosahexaenoic acid is a PPARγ agonist and activates a Nrf2 dependent antioxidant reaction .
Cat. No.: HY-130287
CAS No.: 90780-51-1
Synonyms: (±)16-HDoHE; 16-hydroxy Docosahexaenoic acid; (±)16-HDoHE
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(±)16-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro. It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes. (±)16-HDHA is a potential marker of oxidative stress in brain and retina where DHA is an abundant polyunsaturated fatty acid.
Cat. No.: HY-148944
CAS No.: 124538-05-2
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Didocosahexaenoin, an omega-3 derivative, is a diglyceride of DHA and can be synthesised from DHA triglycerides. Didocosahexaenoin causes significant loss of mitochondrial membrane potential and induces ROS production. Didocosahexaenoin induces apoptosis. Didocosahexaenoin induces stronger cytotoxicity than DHA in human prostate carcinoma cells .
Cat. No.: HY-19886
CAS No.: 92510-91-3
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F 16915, a Docosahexaenoic Acid (DHA, HY-B2167) derivative, is a potent pro-agent of DHA. F 16915 can prevent heart failure-induced atrial fibrillation .
Synonyms: 13,14-EpDPE
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(±)13(14)-EpDPA (13,14-EpDPE) is the product of the reaction of cytochrome P-450 epoxygenase with Docosahexaenoic Acid (DHA).(±)13(14)-EpDPA has antihyperalgesic and vasorelaxative activities .
Cat. No.: HY-171229
CAS No.: 2267338-53-2
1-Acetyl-DHA (Compound 7) is a substrate of the phosphotriesterase homology protein (PHP) and can be hydrolyzed by PHP with a kcat/km value of 100 M -1s -1. The level of 1-Acetyl-DHA is regulated by mTORC1 and is negatively correlated with the nuclear acetate level. 1-Acetyl-DHA plays an important role in cellular metabolism and the regulation of histone acetylation .
Cat. No.: HY-101847
CAS No.: 99584-96-0
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DBHDA is organic compound, which converts cysteine to dehydroalanine (DHA) .
Cat. No.: HY-101541R
CAS No.: 2566-90-7
Synonyms: Methyl docosahexaenoate (Standard); all cis-DHA methyl ester (Standard)
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Docosahexaenoic acid methyl ester (Standard) is the analytical standard of Docosahexaenoic acid methyl ester. This product is intended for research and analytical applications. Docosahexaenoic Acid methyl ester is a methylated docosahexaenoic acid analog which can be intercalated into membrane phospholipids without being oxidized or hydrolyzed.
Cat. No.: HY-130550
CAS No.: 895127-66-9
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
