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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
283 Results for "
T3
" in MedChemExpress (MCE) Product Catalog:
Products (283)
283 Results for "T3" in MCE Product Catalog:
Cat. No.: HY-P992390
Target:
Research Areas:
Cat. No.: HY-114911R
CAS No.: 30748-29-9
Synonyms: DA2370 (Standard); Prenazone (Standard); Zepelin (Standard)
Research Areas:
Feprazone (Standard) is the analytical standard of Feprazone. This product is intended for research and analytical applications. Feprazone (DA2370; Prenazone), an analogue of Phenylbutazone (HY-B0230), is a nonsteroidal anti-inflammatory agent with analgesic and antipyretic activities. Feprazone acts by inhibiting the activity of cyclooxygenase (COX)-2. Feprazone ameliorates free fatty acid (FFA)-induced oxidative stress by reducing the production of mitochondrial reactive oxygen species (ROS). Feprazone can decrease the expression of MMP-2 and MMP-9. Besides, Feprazone can suppress adipogenesis and increase lipolysis in differentiating 3 T3-L1 cells. Feprazone also can be used to research atherosclerosis and obesity [3].
Cat. No.: HY-12753AR
CAS No.: 197431-02-0
Synonyms: SR35021 hydrochloride (Standard)
Research Areas:
Debutyldronedarone hydrochloride (Standard) (SR35021 hydrochloride (Standard)) is the analytical standard of Debutyldronedarone (hydrochloride) (HY-12753A). This product is intended for research and analytical applications. Debutyldronedarone hydrochloride (SR35021 hydrochloride) is a Cytochrome P450 enzyme inhibitor and a Thyroid Hormone Receptor inhibitor, and it is a metabolite of Dronedarone (HY-A0016). Debutyldronedarone hydrochloride inhibits the binding of T3 to TRα1 and TRβ1. Debutyldronedarone hydrochloride reduces the incidence of reperfusion-induced ventricular fibrillation in anesthetized rats, while decreasing their heart rate and blood pressure. Debutyldronedarone hydrochloride can be used in studies related to ventricular fibrillation and atrial fibrillation .
Cat. No.: HY-12753AS
Synonyms: SR35021-d7 hydrochloride
Cat. No.: HY-12753S
CAS No.: 2070015-16-4
Synonyms: SR35021-d7
Cat. No.: HY-W713284
CAS No.: 2734919-82-3
Synonyms: (E)-Octyl methoxycinnamate-d3
Target:
Isotope-Labeled Compounds Cytochrome P450 Estrogen Receptor/ERR Androgen Receptor Thyroid Hormone Receptor
Research Areas:
Octinoxate-d3 is the deuterium labeled Octinoxate (HY-B1234). Octinoxate (Octyl methoxycinnamate) is a thyroid hormone receptor agonist, reducing the levels of triiodothyronine (T3) and thyroxine (T4) and transcription levels of genes related to type II deiodinase (deio2) in Japanese Medaka. Octinoxate is commonly used as a safe ultraviolet (UV) filter used in the aquatic environment. Octinoxate inhibits CYP1A1 and CYP1B1 to regulate hyaluronan (HA) (HY-B0633A) metabolism in a PI3K pathway-dependent manner in human keratinocytes. Octinoxate also exhibits an anti-estrogenic and anti-androgenic effect in vitro and in vivo [3] .
Cat. No.: HY-B1234S
Cat. No.: HY-162376
CAS No.: 2316760-41-3
T3SS-IN-4 (Compound Z-8) is a T3SS inhibitor that can inhibit the expression of Xanthomonas oryzae pv oryzae (Xoo) T3SS-related genes without affecting bacterial growth. T3SS-IN-4 can effectively reduce the hypersensitive response (HR) induced by Xoo in tobacco and lower the pathogenicity of Xoo in rice .
Cat. No.: HY-173598
CAS No.: 930993-54-7
T3SS-1-IN-1 (Compound C26) is a T3SS-1 inhibitor. T3SS-1-IN-1 inhibits the secretion of SipA and the activity of HilD (IC50 values are 29.2 and 16.9 μM, respectively). T3SS-1-IN-1 can be used for the study of anti-virulence of Salmonella .
Cat. No.: HY-12753
CAS No.: 141626-35-9
Synonyms: SR35021
Research Areas:
Debutyldronedarone (SR35021) is a Cytochrome P450 enzyme inhibitor and a Thyroid Hormone Receptor inhibitor, and it is a metabolite of Dronedarone (HY-A0016). Debutyldronedarone inhibits the binding of T3 to TRα1 and TRβ1. Debutyldronedarone reduces the incidence of reperfusion-induced ventricular fibrillation in anesthetized rats, while decreasing their heart rate and blood pressure. Debutyldronedarone can be used in studies related to ventricular fibrillation and atrial fibrillation .
Cat. No.: HY-P78753
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD3G; T3G; CD3 Gamma Subunit Of T-Cell Receptor Complex; T-Cell Antigen Receptor Complex, Gamma Subunit Of T3; T-Cell Surface Glycoprotein CD3 Gamma Chain; CD3g Molecule, Epsilon (CD3-TCR Complex); T-Cell Receptor T3 Gamma Chain; TCR Ti Gamma-Chain V8-J2
Species:
Human
Source:
HEK293
Cat. No.: HY-P71845
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CD3G; T3G; CD3 Gamma Subunit Of T-Cell Receptor Complex; T-Cell Antigen Receptor Complex, Gamma Subunit Of T3; T-Cell Surface Glycoprotein CD3 Gamma Chain; CD3g Molecule, Epsilon (CD3-TCR Complex); T-Cell Receptor T3 Gamma Chain; TCR Ti Gamma-Chain V8-J2
Species:
Cynomolgus
Source:
P. pastoris
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
