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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1112 Results for "
basic
" in MedChemExpress (MCE) Product Catalog:
Products (1112)
1112 Results for "basic" in MCE Product Catalog:
Art. -Nr.: HY-P80705A
Synonyms: ARNT; BHLHE2; Aryl hydrocarbon receptor nuclear translocator; ARNT protein; Class E basic helix-loop-helix protein 2; bHLHe2; Dioxin receptor; nuclear translocator; Hypoxia-inducible factor 1-beta; HIF-1-beta; HIF1-beta
Target:
Forschungsgebiete:
DBCO-PEG2-NHS ester is a click chemistry reagent containing an azide group. DBCO-PEG2-NHS ester is a click chemistry PEG reagent containing NHS ester that is able to react specifically and efficiently with primary amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic condition to form a covalent bond. The hydrophilic PEG spacer arm improves water solubility and provides a long and flexible connection that minimizes steric hindrance involved with ligation. DBCO is commonly used for copper-free Click Chemistry reactions. Reagent grade, for research use only .
Art. -Nr.: HY-D3099
CAS. Nr.: 3078752-74-3
Target:
Forschungsgebiete:
CSMPP is a ratiometric lysosomal pH fluorescent probe with aggregation-induced emission (AIE) properties, which is used for real-time quantitative detection of lysosomal pH changes in living cells and in vivo. CSMPP has a cyanodistyrene backbone, and contains N-methylpiperazine and pyridine groups (pH-responsive); protonation of the pyridine group significantly enhances intramolecular charge transfer (ICT), leading to green fluorescence emission (Ex/Em = 405/503 nm) under neutral/basic conditions and red fluorescence emission (Ex/Em = 405/615 nm) under acidic conditions. CSMPP exhibits high selectivity, reversibility, good biocompatibility and excellent photostability .
Art. -Nr.: HY-P1388F1
Synonyms: CY5-Ahx-Amyloid β-peptide (1-42) (rat/mouse)
Target:
Forschungsgebiete:
Art. -Nr.: HY-W145545
CAS. Nr.: 138906-41-9
Synonyms: 4-Methoxyphenyl 3,4,6-Tri-O-acetyl-2-deoxy-2-phthalimido-beta-D-glucopyranoside
Art. -Nr.: HY-P71282
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SEMA3C; Semaphorin-3C; Prev. SEMAE; Uncharacterized Protein SEMA3C; SemE; Semaphorin E; Sema Domain, Immunoglobulin Domain (Ig), Short basic Domain, Secreted, (Semaphorin) 3C; Semaphorin-E; Semaphorin 3C; Sema E
Species:
Human
Source:
HEK293
Art. -Nr.: HY-108190
CAS. Nr.: 33103-21-8
Target:
Forschungsgebiete:
Tuberactinomycin A is a basic cyclic peptide antibiotic and a group I intron RNA splicing inhibitor, with an IC50 of 10 μM against the G-binding site of bacteriophage T4 group I intron RNA. Tuberactinomycin A exerts antibacterial effects by acting on the initiation and elongation steps of bacterial bacteria ribosomes to inhibit prokaryotic protein synthesis. Tuberactinomycin A competes with guanosine cofactors for binding to the G-binding site of group I intron RNA, forms electrostatic interactions with the RNA backbone, and inhibits the self-splicing of bacteriophage T4 td and sunY group I introns, and its inhibitory activity depends on Mg 2+ concentration. Tuberactinomycin A can be used in studies related to bacterial infections .
Art. -Nr.: HY-183942
CAS. Nr.: 2196246-28-1
USP7-IN-20 is a highly selective USP7 inhibitor that binds allosterically to the allosteric pocket of USP7 in a non-competitive and reversible manner. USP7-IN-20 downregulates MDM2 protein levels and stabilizes p53, thereby inducing p21 expression and enhancing the ubiquitin-dependent degradation of MDM2. USP7-IN-20 effectively binds endogenous USP7 to inhibit cancer cell proliferation, and also induces apoptosis by promoting the cleavage of PARP and caspase 3. USP7-IN-20 can be widely used in cancer-related basic and translational research.
Art. -Nr.: HY-D0185R
CAS. Nr.: 312693-72-4
Category:
Art. -Nr.: HY-DY2032
Target:
Forschungsgebiete:
Methyl Green Staining Solution (Chloroform-Extracted, 1%) is a basic dye stock solution with differential nucleic acid binding activity that distinguishes double-stranded DNA from RNA, and it can be used for assays related to nucleic acid distribution and DNA localization. Methyl Green Staining Solution (Chloroform-Extracted, 1%) functions by competitively binding to the phosphate groups of nucleic acids and stably binds to intact double-stranded DNA; RNA within the oocyte-specific ribonucleoprotein complex specifically binds to this dye, and RNase completely blocks this binding reaction. The nucleic acid recognition of Methyl Green Staining Solution (Chloroform-Extracted, 1%) depends on the size of the dye cation and the intact double-helical structure of DNA .
Art. -Nr.: HY-W250143
CAS. Nr.: 6586-04-5
Art. -Nr.: HY-P70298
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HTN3; Histatin-5; Histatin 3; Histatin-6; HIS2; Histatin-7; basic Histidine-Rich Protein; Histatin-8; Histidine-Rich Protein 3; Histatin-9; Histatin-3; HTN2; Hst 3; HTN5; PB; Hst; Histatin-4
Species:
Human
Source:
E. coli
Art. -Nr.: HY-P73832
Reinheit: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: MAX; BHLHd5; MYC Associated Transcriptional Regulator X; BHLHd6; MYC Associated Factor X; BHLHd7; BHLHd4; BHLHd8; Protein Max; MAX Protein; Class D basic Helix-Loop-Helix Protein 4; BHLHD4; Myc-Associated Factor X; PDMCS
Species:
Human
Source:
Sf9 insect cells
Art. -Nr.: HY-P700514
Reinheit: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: USF1; Upstream Transcription Factor 1; BHLHb11; Major Late Transcription Factor 1; Upstream Stimulatory Factor 1; MLTFI; UEF; Class B basic Helix-Loop-Helix Protein 11; HYPLIP1; BHLHB11; FCHL1; FCHL; MLTF; USF
Species:
Human
Source:
E. coli
Art. -Nr.: HY-P700617
Reinheit: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PCSK6; SPC4; Prev. PACE4; Paired basic Amino Acid Cleaving System 4; Subtilisin-Like Proprotein Convertase 4; Alternative Protein PCSK6; Subtilisin/Kexin-Like Protease PACE4; Subtilisin-Like Protease; Proprotein Convertase Subtilisin/Kexin Type 6; Paired
Species:
Human
Source:
E. coli
Art. -Nr.: HY-P700696
Reinheit: ≥ 90%, as determined by Bis-Tris PAGE.
Synonyms: C1S; Complement C1s Subcomponent; Complement C1s; C1 Esterase; Complement Component 1, S Subcomponent; basic Proline-Rich Peptide IB-1; Complement Component 1 Subcomponent S; EDSPD2
Species:
Human
Source:
HEK293
Art. -Nr.: HY-P702776
Reinheit: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MYCN; Neuroblastoma MYC Oncogene; Prev. NMYC; Oncogene NMYC; BHLHe37; MYCNsORF; N-Myc; MYCNsPEP; V-Myc Avian Myelocytomatosis Viral Oncogene Neuroblastoma Derived Homolog; BHLHE37; Class E basic Helix-Loop-Helix Protein 37; FGLDS1; N-Myc Proto-Oncogene Pr
Species:
Human
Source:
Sf9 insect cells
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
