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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
200 Results for "
Second-generation
" in MedChemExpress (MCE) Product Catalog:
Products (200)
200 Results for "Second-generation" in MCE Product Catalog:
Cat. No.: HY-100660
CAS No.: 113740-61-7
Target:
Research Areas:
Cetirizine Impurity B is an impurity of Cetirizine (HY-17042), a selective second-generation histamine H1 receptor antagonist .
Cat. No.: HY-K2030
MCE Lentivirus Packaging Kit is based on the second-generation lentiviral packaging system and is also compatible with both second- and third-generation packaging plasmids. Lentiviruses produced using this kit exhibit high infection efficiency and a broad host range, enabling stable and sustained expression of exogenous genes in host cells.
Cat. No.: HY-10452R
CAS No.: 1239908-20-3
Synonyms: MLN9708 (Standard)
Target:
Research Areas:
Ixazomib citrate (Standard) is the analytical standard of Ixazomib citrate (HY-10452). This product is intended for research and analytical applications. Ixazomib citrate (MLN9708) is a selective, orally active, second-generation proteasome inhibitor. Ixazomib citrate can be used for the study of a broad range of human malignancies .
Cat. No.: HY-101212R
CAS No.: 1070790-89-4
Synonyms: CYC065 (Standard)
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Research Areas:
Fadraciclib (Standard) is the analytical standard of Fadraciclib (HY-101212). This product is intended for research and analytical applications. Fadraciclib (CYC065) is a second-generation, orally available ATP-competitive inhibitor of CDK2/CDK9 kinases with IC50s of 5 and 26 nM, respectively .
Cat. No.: HY-187733
CAS No.: 77016-85-4
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Plomestane is an orally active second-generation steroidal aromatase inhibitor that, as an enzyme-activated pseudosubstrate, is converted via NADPH-dependent catalysis into a reactive intermediate, which covalently binds to aromatase to produce irreversible inhibition, thereby persistently suppressing peripheral aromatase activity. Plomestane can be used for the study of hormone-dependent breast cancer .
Cat. No.: HY-I0021R
CAS No.: 125602-71-3
Research Areas:
Bepotastine (Standard) is the analytical standard of Bepotastine. This product is intended for research and analytical applications. Bepotastine is a selective and orally active second-generation histamine H1 receptor antagonist, can suppress the expression of nerve growth factor (NGF). Bepotastine has the potential for allergic rhinitis, allergic conjunctivitis and urticaria/pruritus research .
Cat. No.: HY-112714A
CAS No.: 2097784-79-5
Synonyms: BMS-955176 oxalate
GSK3532795 oxalate is a potent, orally active, second-generation HIV-1 maturation inhibitor, with EC50s of 1.9, 10.2, 2.7 and 13 nM for HIV-1 WT, HIV-1 WT(human serum), HIV-1 V370A, and HIV-1 ΔV370, respectively .
Cat. No.: HY-112714B
CAS No.: 2023808-13-9
Synonyms: BMS-955176 hydrochloride
GSK3532795 hydrochloride is a potent, orally active, second-generation HIV-1 maturation inhibitor, with EC50s of 1.9, 10.2, 2.7 and 13 nM for HIV-1 WT, HIV-1 WT(human serum), HIV-1 V370A, and HIV-1 ΔV370, respectively .
Synonyms: TRX-E-002-1
Cantrixil (TRX-E-002-1), an active enantiomer of TRX-E-002, is a second-generation super-benzopyran (SBP) compound. Cantrixil increases phosphorylated c-Jun levels resulting in caspase-mediated apoptosis in ovarian cancer cells. Cantrixil has potent pan anti-cancer activity against a broad range of cancer phenotypes .
Cat. No.: HY-150236
Purity: 95.72%
Cat. No.: HY-76200R
CAS No.: 137234-62-9
Synonyms: UK-109496 (Standard)
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Target:
Cat. No.: HY-A0015S
Cat. No.: HY-B0005S
CAS No.: 1246833-71-5
Cat. No.: HY-B0656S
CAS No.: 934295-48-4
Synonyms: LY307640-d4
Synonyms: BMS-955176
GSK3532795 (BMS-955176) is a potent, orally active, second-generation HIV-1 maturation inhibitor, with EC50s of 1.9, 10.2, 2.7 and 13 nM for HIV-1 WT, HIV-1 WT(human serum), HIV-1 V370A, and HIV-1 ΔV370, respectively .
Cat. No.: HY-12532S
CAS No.: 1189961-39-4
Cat. No.: HY-A0015R
CAS No.: 190786-44-8
Research Areas:
Bepotastine (besilate) (Standard) is the analytical standard of Bepotastine (besilate). This product is intended for research and analytical applications. Bepotastine besilate is a selective and orally active second-generation histamine H1 receptor antagonist, can suppress the expression of nerve growth factor (NGF). Bepotastine besilate has the potential for allergic rhinitis, allergic conjunctivitis and urticaria/pruritus research .
Cat. No.: HY-B0005R
CAS No.: 89778-27-8
Synonyms: Z-Toremifene citrate (Standard); NK 622 (Standard); FC-1157a (Standard)
Toremifene (citrate) (Standard) is the analytical standard of Toremifene (citrate). This product is intended for research and analytical applications. Toremifene citrate (Z-Toremifene citrate) is a second-generation selective estrogen-receptor modulator (SERM) in development for the prevention of osteoporosis. Toremifene citrate also potent inhibits infectious EBOV Zaire and Marburg (MARV) with IC50 of 0.07 µM and 2.6 µM, respectively .
Cat. No.: HY-B0656AS
Synonyms: LY307640-d4 sodium
Cat. No.: HY-100661R
CAS No.: 346451-15-8
Research Areas:
Cetirizine Impurity D (Standard) is the analytical standard of Cetirizine Impurity D. This product is intended for research and analytical applications. Cetirizine Impurity D is an impurity of Cetirizine. Cetirizine, a second-generation antihistamine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
