192 Results for "

visualize

" in MedChemExpress (MCE) Product Catalog:
Products (192)

192 Results for "visualize" in MCE Product Catalog:

Cat. No.: HY-103329R
CAS No.: 956605-71-3
Synonyms: MM22 (Standard); Biotinylated N-arachidonoylethanolamine (Standard)
Research Areas:  

Others

b-AEA (Standard) is the analytical standard of b-AEA (HY-103329). This product is intended for research and analytical applications. b-AEA (MM22) is a biotinylated endocannabinoid analog with probe activity. b-AEA is able to accumulate intracellularly in a similar manner to the parent compound AEA. b-AEA does not interact with other components of the endocannabinoid system and therefore does not interfere with their function. b-AEA can be used to visualize the accumulation and intracellular distribution of endocannabinoids .
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Cat. No.: HY-109513R
CAS No.: 107793-72-6
Research Areas:  

Others

Ioxilan (Standard) is the analytical standard of Ioxilan. This product is intended for research and analytical applications. Ioxilan is a low-osmolar, nonionic and tri-iodinated diagnostic contrast agent. Ioxilan is also an X-ray contrast agent for excretory urography and contrast enhanced computed tomographic (CECT) imaging of the head and body. Intravascular injection results in opacification of vessels in the path of flow of the contrast medium, permitting radiographic visualization of the internal structures of the human body until significant hemodilution occurs .
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Cat. No.: HY-128522
CAS No.: 2436544-27-1
Purity:  99.59%
Target:  

Ras

Research Areas:  

Cancer

ARS-1323-alkyne is a covalent inhibitor probe that covalently binds to the Switch-II pocket (S-IIP) of the KRAS G12C mutant protein. ARS-1323-alkyne visualizes the covalent modification of KRAS G12C and quantitatively measures the binding efficiency of the inhibitor to the target. ARS-1323-alkyne can be used to validate the target occupancy of KRAS G12C inhibitors and the synergistic mechanism of combination therapy .
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Cat. No.: HY-179492
CAS No.: 3033951-64-0
Target:  

hnRNP

Research Areas:  

Neurological Disease

ACI-19278 is a TDP-43 PET tracer with an average Kd of 25 nM. ACI-19278 only binds to pathological TDP-43 aggregates and does not cross-react with Aβ, Tau, etc. [ 18F]ACI-19278 successfully visualized the TDP-43 pathology in the human brain through positron emission computed tomography. ACI-19278 can be used for in vivo diagnosis of TDP-43 protein lesions .
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Cat. No.: HY-188058
CAS No.: 208403-22-9
Research Areas:  

Others

Biotin-14-CTP is a modified cytidine triphosphate analog, as well as a non-terminating, non-processable nucleotide analog and labeling reagent. Biotin-14-CTP incorporates into nascent RNA strands during transcription elongation, enabling immunolabeling-based visualization of transcription sites. The incorporation of Biotin-14-CTP is inhibited by α-Amanitin (HY-19610), indicating that it can be utilized by RNA polymerase II .
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Cat. No.: HY-D3113
Target:  

Fluorescent Dye

Research Areas:  

Cancer

BF6 is a blood-brain barrier permeable NIR probe. BF6 can diffuse from intracranial blood vessels into brain tissue, enabling visualization of brain structures and differentiation between glioblastoma (GBM) and normal tissues. The absorption peaks of BF6 in DMSO and FBS range from 727 to 859 nm, with a broad fluorescence emission band spanning 800 to 1400 nm; its emission wavelength falls within the NIR-II region (800-1400 nm) .
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Cat. No.: HY-D3159
CAS No.: 2304942-78-5
Research Areas:  

Others

BTC1070 is an anti-quenching pentamethine cyanine NIR-II fluorescent probe. BTC1070 exhibits high brightness and excellent photostability in aqueous solution (Ex/Em = 1015/1065 nm). BTC1070 can clearly visualize lymphatic structures after intradermal injection, and produces a ratiometric fluorescence response in the acidic range to non-invasively quantify gastric pH. BTC1070 is applicable to studies related to in vivo deep tissue imaging and gastric pH sensing .
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Cat. No.: HY-D3353
CAS No.: 2766510-90-9
PSMA-SulfoCy7 is a high-affinity imaging agent targeting PSMA/GCPII (with a Ki of 18.1 nM for human PSMA). PSMA-SulfoCy7 regulates PSMA-dependent NAAG hydrolysis. PSMA-SulfoCy7 exhibits excellent in vivo imaging capability, enabling clear visualization of PSMA-expressing tumors in xenograft models, with no obvious toxicity even at a dose of 87.9 mg/kg. PSMA-SulfoCy7 is widely used in prostate cancer-related studies .
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Cat. No.: HY-P11088
CAS No.: 1311293-04-5
VCAM1 binding peptide is a VCAM1 binder with internalization activity. VCAM1 binding peptide can be labeled with 5-FAM. VCAM1 binding peptide serves as a component of biosensing systems for visualizing in vitro VCAM1 endocytic pathways. VCAM1 binding peptide forms the research and development basis for MacroP and NAMP, PET radiotracers targeting VCAM1. VCAM1 binding peptide is applicable to studies related to atherosclerosis .
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Cat. No.: HY-P11088A
VCAM1 binding peptide acetate is a VCAM1 binder with internalization activity. VCAM1 binding peptide acetate can be labeled with 5-FAM. VCAM1 binding peptide acetate serves as a component of biosensing systems for visualizing in vitro VCAM1 endocytic pathways. VCAM1 binding peptide acetate forms the research and development basis for MacroP and NAMP, PET radiotracers targeting VCAM1. VCAM1 binding peptide acetate is applicable to studies related to atherosclerosis .
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Cat. No.: HY-P11859
Research Areas:  

Cancer

NP1 is a NOTA-chelated linear precursor based on the ROR1-targeting peptide. After labeling with [ 18F]AlF, NP1 yields [ 18F]AlF-NP1, a PET imaging probe with excellent ROR1 specificity (KD = 141.7 nM), rapid tumor uptake and high target-to-background ratio, which is suitable for non-invasive visualization of various ROR1-overexpressing tumors .
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Cat. No.: HY-121364
CAS No.: 1416130-06-7
Research Areas:  

Others

Bodilisant is a histamine H3 receptor (hH3R) ligand and imaging/labeling agent, with a Ki value of 6.51 nM for hH3R. Bodilisant binds to hH3R to produce strong green fluorescence, localizes to the extracellular membrane without internalization, and generates clear, displaceable fluorescent labeling of hH3R in native human brain tissues. Bodilisant serves as a pharmacological tool to visualize the distribution of hH3R via fluorescence confocal laser scanning microscopy .
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Cat. No.: HY-13443F2
Synonyms: Exendin-4-Cys(Cy5)
Target:  

Fluorescent Dye

Research Areas:  

Metabolic Disease

Exendin-4, Cy5-labeled (Exendin-4-Cys(Cy5)) is a covalently linked Cy5 fluorescent group to Exendin-4 (HY-13443), a GLP-1 receptor agonist. Exendin-4, Cy5-labeled enables the visualization imaging of β cells in vivo, especially for evaluating the expression dynamics of GLP-1R in type 2 diabetes models .
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Cat. No.: HY-158082A
Synonyms: Tetramethyl rhodamine isothiocyanate glucan, MW 20000
TRITC-dextran, MW 20000 (Tetramethyl rhodamine isothiocyanate glucan, MW 20000) is a fluorescent dye, with the molecular weight of 20 kD. TRITC-dextran MW 20000 exhibits an excitation wavelength of 555 nm. TRITC-dextran MW 20000 is vessel penetrate, which could label blood plasma to visualize the vasculature. TRITC-dextran MW 20000 is utilized in drug delivery for the stability of TRITC over a wide pH range (i.e. pH 2–11) and resistance to photo-bleaching .
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Cat. No.: HY-D1366
CAS No.: 2183440-68-6
Target:  

Fluorescent Dye

Research Areas:  

Others

Sulfo-Cyanine5.5 carboxylic acid is a Fluorescent dye. Sulfo-Cyanine5.5 carboxylic acid emits red fluorescence, with a peak absorption wavelength of 673 nm. Sulfo-Cyanine5.5 carboxylic acid can be used to visualize aqueous sub-compartments and phase separation in synthetic multi-compartment microstructures. Sulfo-Cyanine5.5 carboxylic acid can serve as an intravenous contrast agent for in vivo cerebral perfusion imaging, mapping hemodynamics and perfusion regions .
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Cat. No.: HY-D1366A
CAS No.: 2183440-69-7
Target:  

Fluorescent Dye

Research Areas:  

Others

Sulfo-Cyanine5.5 carboxylic acid potassium is a Fluorescent dye. Sulfo-Cyanine5.5 carboxylic acid potassium emits red fluorescence, with a peak absorption wavelength of 673 nm. Sulfo-Cyanine5.5 carboxylic acid potassium can be used to visualize aqueous sub-compartments and phase separation in synthetic multi-compartment microstructures. Sulfo-Cyanine5.5 carboxylic acid potassium can serve as an intravenous contrast agent for in vivo cerebral perfusion imaging, mapping hemodynamics and perfusion regions .
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Cat. No.: HY-D2327
CAS No.: 3020859-80-4
DPP-8/9 probe-1 (compound 20) is a fluorescent probe targeting Dipeptidyl Peptidase DPP8/9, which can be selectively labeled and visualized in vitro by fluorescence microscopy Active DPP8/9. DPP-8/9 probe-1 contains a nitrobenzoxadiazole (NBD) tag and has high affinity and selectivity for DPP8/9 over related S9 family members (IC50 of 210 nM and 15 nM, respectively) .
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Cat. No.: HY-D2982
CAS No.: 1978301-38-0
BTP9-Neu5Ac is a fluorescent imaging probe specifically designed for detecting the neuraminidase (NA) sialidase activity of influenza viruses. BTP9-Neu5Ac can visualize the intracellular Golgi localization of the viral NA activity. BTP9-Neu5Ac can be used for precise and temporal monitoring of the key enzyme activities during the viral life cycle .
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Cat. No.: HY-D3174
CAS No.: 2688758-23-6
PiF is a fluorescent probe with high specificity for pancreatic β-cells (Ex/Em = 535 nm/565 nm), and its fluorescence signal increases significantly with elevated insulin concentrations in in vitro experiments. PiF enables visualization of rat and human islets transplanted via the portal vein in mouse livers with low liver background signals. The fluorine atom of PiF can be replaced by radioactive 18F to prepare a PET tracer. PiF can be used for research on type 1 diabetes .
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Cat. No.: HY-D3211
CAS No.: 2442502-32-9
HJTA is a selective, pH/GSH dual-responsive Fluorescent probe and anticancer agent. HJTA selectively undergoes an enzymatic reaction with GSTπ. HJTA induces Apoptosis and Autophagy by regulating the expression of apoptotic and autophagic proteins. HJTA exhibits pH- and GSH-dual-responsive fluorescence in tumor cells. HJTA selectively illuminates tumor tissues, enabling precise in situ visualization of colon tumors. HJTA exerts anticancer effects against colon cancer. HJTA can be used for colon cancer research .
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