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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1511 Results for "
differentiation
" in MedChemExpress (MCE) Product Catalog:
Products (1511)
1511 Results for "differentiation" in MCE Product Catalog:
Cat. No.: HY-P992076
Cat. No.: HY-L013
3,961 compounds
Neuronal Signaling is involved in the regulation of the mechanisms of the central nervous system (CNS) such as its structure, function, genetics and physiology as well as how this can be applied to understand diseases of the nervous system. Every information processing system in the CNS is composed of neurons and glia, neurons have evolved unique capabilities for intracellular signaling (communication within the cell) and intercellular signaling (communication between cells). G protein-coupled receptors (GPCRs), including 5-HT receptor, histamine receptor, opioid receptor, etc. are the largest class of sensory proteins and are important therapeutic targets in Neuronal Signaling. Besides, Notch signaling, such as β- and γ-secretase, also plays multiple roles in the development of the CNS including regulating neural stem cell (NSC) proliferation, survival, self-renewal and differentiation. GPCR dysfunction caused by receptor mutations and environmental challenges contributes to many neurological diseases. Notch signaling in neurons, glia, and NSCs is also involved in pathological changes that occur in disorders such as stroke, Alzheimer's disease and CNS tumors. Thus, targeting Neuronal Signaling, such as notch signaling and GPCRs, can be used as therapeutic interventions for several different CNS disorders.
MCE designs a unique collection of 3,961 Neuronal Signaling-related compounds that act as a useful tool for the research of neuronal regulation and neuronal diseases.
Cat. No.: HY-P705292
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CD8A; Leu2 T-Lymphocyte Antigen; Prev. CD8; T-Cell Antigen Leu2; T-Cell Surface Glycoprotein CD8 Alpha Chain; T Cell Co-Receptor; T-Lymphocyte differentiation Antigen T8/Leu-2; T8 T-Cell Antigen; CD8alpha; CD8a Antigen; P32; IMD116; CD8 Antigen, Alpha Polypeptide (P32); Leu2; CD8a Molecule; MAL; CD8 Subunit Alpha; OKT8 T-Cell Antigen
Species:
Cynomolgus
Source:
HEK293
Cat. No.: HY-N0353R
CAS No.: 13657-68-6
Synonyms: (+)-Curdione (Standard)
Cat. No.: HY-P990252
Target:
Research Areas:
Cat. No.: HY-L252
76 compounds
Carbohydrate metabolism serves as a central hub for energy supply and biosynthesis in living organisms and plays a critical role in the onset and progression of various diseases. In recent years, studies have shown that tumor cells reprogram their energy metabolism through aerobic glycolysis (the Warburg effect) to support rapid proliferation. Immune cells also rely on specific carbohydrate metabolic pathways to regulate their activation and differentiation states, while disorders such as diabetes and metabolic syndrome arise directly from dysregulation of carbohydrate metabolism. In addition, enzymes and key metabolic nodes involved in carbohydrate metabolism have become important targets for drug discovery, and therapeutic strategies targeting glycolysis, the pentose phosphate pathway, and energy metabolism are continuously advancing the treatment of cancer and metabolic diseases. Therefore, systematic analysis of carbohydrate metabolic networks and their associated metabolites is of great significance for elucidating disease mechanisms and developing novel therapeutic approaches.
The MCE Carbohydrate Metabolism Metabolite Library is constructed based on classical carbohydrate metabolic pathways and contains 76 metabolites. It systematically integrates key metabolic networks, including glycolysis, the pentose phosphate pathway, the tricarboxylic acid (TCA) cycle, monosaccharide metabolism, and sugar acid interconversions. The library comprehensively covers core metabolic nodes from glucose uptake and utilization to energy production and biosynthesis, while also incorporating important upstream and downstream intermediates. It enables accurate representation of intracellular metabolic flux dynamics and is well suited for applications such as metabolic flux analysis, target validation, and mechanistic studies. Furthermore, it provides robust support for multi-omics integration and the development of precision intervention strategies.
Cat. No.: HY-P87164
Synonyms: CAP20 antibody; CDK-interacting protein 1 antibody; CDKI antibody; CDKN1 antibody; Cdkn1a antibody; CDN1A_HUMAN antibody; CIP1 antibody; Cyclin Dependent Kinase Inhibitor 1A antibody; Cyclin-dependent kinase inhibitor 1 antibody; Cyclin-dependent kinase inhibitor 1A (P21) antibody; CAP20 antibody; CDK-interacting protein 1 antibody; CDKI antibody; CDKN1 antibody; Cdkn1a antibody; CDN1A_HUMAN antibody; CIP1 antibody; Cyclin Dependent Kinase Inhibitor 1A antibody; Cyclin-dependent kinase inhibitor 1 antibody; Cyclin-dependent kinase inhibitor 1A (P21) antibody; Cyclin-dependent kinase inhibitor 1A (p21, Cip1) antibody; DNA Synthesis Inhibitor antibody; MDA-6 antibody; MDA6 antibody; Melanoma differentiation-associated protein 6 antibody; Melanoma differentiation-associated protein antibody; p21 antibody; P21 protein antibody; p21CIP1 antibody; p21Cip1/Waf1 antibody; p21WAF antibody; PIC1 antibody; SDI1 antibody; SLC12A9 antibody; WAF1 antibody; Wild type p53 activated fragment 1 (WAF1) antibody; Wild type p53 activated fragment 1 antibody; Wildtype p53-activated fragment 1 antibody;
Cat. No.: HY-P86669
Synonyms: Interleukin-4; IL4; IL 4; B cell growth factor 1; B cell IgG differentiation factor; B Cell Stimulatory Factor 1; BCGF 1; BCGF1; Binetrakin; BSF 1; BSF1; HCGF; Hodgkin’s Cell Growth Factor; IA Inducing Factor; IGG1 induction factor; Il4e12; Interleukin 4; Interleukin 4, isoform 1; Interleukin4; Lymphocyte stimulatory factor 1; Macrophage fusion factor; Mast cell growth factor 2; MCGF2; MFF; MGC79402; Pitrakinra; T cell growth factor 2; TCGF2; IL4_HUMAN; B-cell stimulatory factor 1; BSF-1.
Cat. No.: HY-P705623
Purity: ≥ 95%, as determined by SDS-PAGE.
Synonyms: CD36; Leukocyte differentiation Antigen CD36; CD36 Molecule (CD36 Blood Group); Thrombospondin Receptor; Platelet Glycoprotein 4; CD36 Antigen; GPIIIB; PAS-4; GPIV; CD36 Molecule (CD36 Blood Group) Transcript; GP3B; Scavenger Receptor Class B, Member 3; FAT; Scavenger Receptor Class B Member 3; GP4; Mutant Thrombospondin Receptor; Platelet Glycoprotein IV; Platelet Collagen Receptor; Fatty Acid Translocase; CD36 Molecule Isoform 2; Glycoprotein IIIb; Cluster Determinant 36; SCARB3; PAS-4 Protein; PAS IV; BDPLT10; CD36 Antigen (Collagen Type I Receptor, Thrombospondin Receptor); CHDS7; CD36 Molecule (Thrombospondin Receptor); PASIV
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
