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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
174 Results for "
ABT
" in MedChemExpress (MCE) Product Catalog:
Products (174)
174 Results for "ABT" in MCE Product Catalog:
Synonyms: Ebanicline dihydrochloride; ABT-594 dihydrochloride
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Tebanicline dihydrochloride (Ebanicline dihydrochloride) is a nAChR modulator with potent, orally effective analgesic activity. It inhibits the binding of cytisine to α4β2 neuronal nAChRs with a Ki of 37 pM .
Cat. No.: HY-14316B
CAS No.: 203564-54-9
Synonyms: Ebanicline hydrochloride; ABT-594 hydrochloride
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Tebanicline hydrochloride (Ebanicline hydrochloride) is a nAChR modulator with potent, orally effective analgesic activity. Tebanicline hydrochloride inhibits the binding of cytisine to α4β2 neuronal nAChRs with a Ki of 37 pM .
Cat. No.: HY-14316C
CAS No.: 198283-74-8
Synonyms: Ebanicline tosylate; ABT-594 tosylate
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Tebanicline tosylate, an analogue of epibatidine, is a neuronal nicotinic acetylcholine receptor agonist. Tebanicline tosylate exhibits potent antinociceptive effects and has a high affinity for the α4β2 neuronal nicotinic acetylcholine receptor subunit in the central nervous system.
Cat. No.: HY-10130R
CAS No.: 912445-05-7
Synonyms: ABT-888 dihydrochloride (Standard)
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Veliparib (dihydrochloride) (Standard) is the analytical standard of Veliparib (dihydrochloride) (HY-10130). This product is intended for research and analytical applications. Veliparib (dihydrochloride) is a potent inhibitor of PARP1 and PARP2 with Kis of 5.2 nM and 2.9 nM in cell-free assays, respectively.
Cat. No.: HY-13997R
CAS No.: 1258226-87-7
Synonyms: ABT-267 (Standard)
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Ombitasvir (Standard) is the analytical standard of Ombitasvir. This product is intended for research and analytical applications. Ombitasvir is a potent inhibitor of the hepatitis C virus protein NS5A, with EC50s of 0.82 to 19.3 pM against HCV genotypes 1 to 5, and 366 pM against genotype 6a.
Cat. No.: HY-160718
CAS No.: 171752-56-0
Synonyms: ABT-431; DAS-431
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Adrogolide is an A-86929 (HY-171472) prodrug and dopamine D1 receptor agonist. Adrogolide is converted rapidly in plasma to A-86929. Adrogolide improves behavioral disability and locomotor activity scores. Adrogolide can also attenuate the ability of Cocaine to induce Cocaine-seeking behavior. Adrogolide can be used in the research of Parkinson's disease .
Cat. No.: HY-17634R
CAS No.: 1365970-03-1
Synonyms: ABT-493 (Standard)
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Glecaprevir (Standard) is the analytical standard of Glecaprevir. This product is intended for research and analytical applications. Glecaprevir is a novel HCV NS3/4A protease inhibitor, with IC50 values ranging from 3.5 to 11.3 nM. Glecaprevir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 4.09 μM .
Cat. No.: HY-P99627
CAS No.: 1708936-80-4
Synonyms: NV-02; PG110; ABT-110
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Cat. No.: HY-103389R
CAS No.: 1614-12-6
Synonyms: ABT (Standard); 3-Aminobenzotriazole (Standard)
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1-Aminobenzotriazole (Standard) is the analytical standard of 1-Aminobenzotriazole. This product is intended for research and analytical applications. 1-Aminobenzotriazole is a nonspecific and irreversible inhibitor of cytochrome P450 (P450).
Cat. No.: HY-P99391B
CAS No.: 1781223-80-0
Synonyms: ABT-700 (WT IgG1); ABBV-400 Antibody (WT IgG1)
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Telisotuzumab (WT IgG1) is a monoclonal antibody that retains the natural wild-type IgG1 Fc structure without engineering modification. Telisotuzumab (HY-P99391) is a humanized IgG1 anti-c-Met monoclonal antibody whose Fc hinge region has been engineered to introduce additional cysteine coupling sites for targeted drug conjugation .
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(Rac)-ABT-202 dihydrochloride is a racemate of ABT-202. ABT-202 is an agonist of nicotinic acetylcholine receptors (nAChRs) and can be used as an analgesic .
Cat. No.: HY-10635AR
CAS No.: 808756-70-9
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(S)-ABT-102 (Standard) is the analytical standard of (S)-ABT-102 (HY-10635A). This product is intended for research and analytical applications. (S)-ABT-102 is a TRPV1 Antagonist, with an IC50 of 123 nM. (S)-ABT-102 has analgesic activity .
Cat. No.: HY-10635A
CAS No.: 808756-70-9
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(S)-ABT-102 is a TRPV1 Antagonist, with an IC50 of 123 nM. (S)-ABT-102 has analgesic activity .
Cat. No.: HY-131001
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DPNB-ABT594 is a nitrobenzyl-caged ABT594 (HY-14316A) and activates nAChRs containing the α4β2 subunits with good selectivity than the α7 subunit. DPNB-ABT594 can be used to map the distribution of nAChRs on neurons of the medial habenula (MHb) and helps to gain a deeper understanding of the nAChR-mediated Ca 2+ signalling in the MHb .
Cat. No.: HY-14588A
CAS No.: 1798014-18-2
Synonyms: (rel)-ABT-378
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rel-Lopinavir ((rel)-ABT-378) is a drug impurity.
Synonyms: Desmorpholinyl ABT-263-NH-Me
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Desmorpholinyl navitoclax-NH-Me (Desmorpholinyl ABT-263-NH-Me) is an N-methylamino-substituted derivative of Navitoclax (HY-10087) and a BCL-XL-targeting PROTAC precursor. Desmorpholinyl navitoclax-NH-Me is used for the synthesis of BCL-XL-targeting PROTACs and related research .
Cat. No.: HY-14588S
CAS No.: 1322625-54-6
Synonyms: (rel)-ABT-378-d8
Cat. No.: HY-90001S3
CAS No.: 1217720-20-1
Synonyms: rel-ABT 538-d6; rel-RTV-d6
Synonyms: (1S,2R)-ABT-957
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(1S,2R)-Alicapistat ((1S,2R)-ABT-957) is an orally active selective inhibitor of human calpains 1 and 2 for the potential application of Alzheimer's disease (AD) . (1S,2R)-Alicapistat mitigates the metabolic liability of carbonyl reduction and inhibits calpain 1 with an IC50 value of 395 nM .
Cat. No.: HY-167869
CAS No.: 819058-88-3
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A-849529 is an acid metabolite of ABT-869 (HY-50751). ABT-869 is a potent and orally active multi-target inhibitor of VEGFR and PDGFR family .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
