Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
(S,R,S)-AHPC-PEG6-C4-Cl
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "(S,R,S)-AHPC-PEG6-C4-Cl" in MCE Product Catalog:
Synonyms: VH032-PEG6-C4-Cl; VHL Ligand-Linker Conjugates 10; E3 ligase Ligand-Linker Conjugates 9
Research Areas:
(S,R,S)-AHPC-PEG6-C4-Cl is a conjugate of ligands for E3 and 25-atom-length linker. The connector of linker is Halogen group. (S,R,S)-AHPC-PEG6-C4-Cl incorporates the (S,R,S)-AHPC based VHL ligand and 6-unit PEG linker. (S,R,S)-AHPC-PEG6-C4-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays .
Cat. No.: HY-176366
CAS No.: 2361117-11-3
Research Areas:
AHPC-PEG6-CH2COOH is an E3 ligase ligand-linker conjugate that incorporates a VHL ligand and 6-unit PEG linker (HY-122702). AHPC-PEG6-CH2COOH can be used for synthesis of PROTAC CMP98 (HY-136257) .
Cat. No.: HY-W998296
Research Areas:
(S,R,S)-AHPC-PEG6-C4-NH2 hydrochloride is an E3 ligase ligand-linker conjugate containing a VHL ligand and linker based on (S,R,S)-AHPC. (S,R,S)-AHPC-PEG6-C4-NH2 hydrochloride can be used to synthesize PROTAC.
Cat. No.: HY-W590583
CAS No.: 2767219-19-0
Target:
Research Areas:
(S, R, S)-AHPC-PEG6-Azide is a click chemistry PROTAC linker that incorporates an E3 ligase ligand with a PEG6 arm to empower PROTAC research & discovery. The hydrophilic PEG spacer increases the solubility of a compound in aqueous media. Azide enables click chemistry with alkyne, DBCO, or BCN molecule.
Cat. No.: HY-W800760
CAS No.: 2839806-94-7
Research Areas:
(S, R, S)-AHPC-PEG6-Tos is a combination of a von Hippel-Lindau (VHL)-recruiting ligand and PEGylated crosslinker with a tosyl group. The tosyl group is a good leaving group for nucleophilic substitution reactions. (S, R, S)-AHPC-PEG2-Tos is useful for synthesis of PROTAC compounds and molecules for targeted protein degradation.
Cat. No.: HY-103606R
CAS No.: 1835705-59-3
Synonyms: VH032-PEG6-C4-Cl (Standard); VHL Ligand-Linker Conjugates 10 (Standard); E3 ligase Ligand-Linker Conjugates 9 (Standard)
Research Areas:
(S,R,S)-AHPC-PEG6-C4-Cl (Standard) is the analytical standard of (S,R,S)-AHPC-PEG6-C4-Cl (HY-103606). This product is intended for research and analytical applications. (S,R,S)-AHPC-PEG6-C4-Cl is a conjugate of ligands for E3 and 25-atom-length linker. The connector of linker is Halogen group. (S,R,S)-AHPC-PEG6-C4-Cl incorporates the (S,R,S)-AHPC based VHL ligand and 6-unit PEG linker. (S,R,S)-AHPC-PEG6-C4-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays .
Cat. No.: HY-163209
CAS No.: 2763910-08-1
Synonyms: (S,R,S)-AHPC-PEG6-NH2 hydrochloride
Research Areas:
VH 032 amide-PEG6-amine hydrochloride (Step 4) is a functionalized von-Hippel-Lindau protein-ligand (VHL) for PROTAC development, consisting of an E3 ligand and a PEG6 ligand. Terminal amines can be coupled to target protein ligands .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
