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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
22 Results for "
ddC
" in MedChemExpress (MCE) Product Catalog:
Products (22)
22 Results for "ddC" in MCE Product Catalog:
17
Target:
Research Areas:
Diethyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-dicarboxylate is an orally active porphyrin inducer and ferrochelatase inhibitor. Diethyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-dicarboxylate can induce small bile duct obstruction in mice, resulting in blocked bile excretion and causing cholestasis. Long-term use of Diethyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-dicarboxylate can cause damage to bile duct epithelial cells, inflammatory responses, and liver fibrosis. Diethyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-dicarboxylate can be used to simulate the pathological features of cholestatic liver diseases such as sclerosing cholangitis (PSC) .
Cat. No.: HY-139997
CAS No.: 2140806-84-2
DDC-01-163 is an allosteric PROTAC degrader targeting EGFR. DDC-01-163 is dependent on the ubiquitin–proteasome system. DDC-01-163 can selectively inhibit the proliferation of L858R/T790M (L/T) mutant Ba/F3 cells. DDC-01-163 is effective against Osimertinib (HY-15772)-resistant cells with L/T/C797S and L/T/L718Q EGFR mutations. DDC-01-163 exhibits enhanced anti-proliferative activity against L858R/T790M EGFR-Ba/F3 cells when combined with the ATP-site EGFR inhibitor Osimertinib. DDC-01-163 can be used for the study of non-small cell lung cancer .
Synonyms: 2',3'-Dideoxycytidine (Standard); ddC (Standard); Dideoxycytidine (Standard)
Research Areas:
Zalcitabine (Standard) is the analytical standard of Zalcitabine. This product is intended for research and analytical applications. Zalcitabine is a potent nucleoside analogue reverse transcriptase inhibitor used in the treatment of HIV infection.
Cat. No.: HY-151048
CAS No.: 2140807-58-3
JBJ-07-149 is an inhibitor for EGFRL858R/T790M with an IC50 of 1.1 nM. JBJ-07-149 inhibits the proliferation of cell Ba/F3 with IC50 of 4.9 μM and 0.148 μM, without and with presence of Cetuximab (HY-P9905). JBJ-07-149 can be used as ligand for target protein in synthesis of DDC-01-163 (HY-139997) .
Cat. No.: HY-156179
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DDC 2′,3′-O-disulfate (compound 4) prevents the fibrillization and oligomerization of Aβ42. DDC 2′,3′-O-disulfate has the potential for Alzheimer's disease (AD) research .
Cat. No.: HY-RS03608
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DDC Human Pre-designed siRNA Set A contains three designed siRNAs for DDC gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-156180
Target:
Research Areas:
DDC 3′-O-β-D glucuronide (compound 5) is a drug metabolite that can prevent the fibrillization and oligomerization of Aβ42. DDC 3′-O-β-D glucuronide has potential for the research of Alzheimer's disease .
Cat. No.: HY-W784611
CAS No.: 195375-65-6
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3'-NH-Tr-2',3'-ddC(Bz)-5'-CE-Phosphoramidite is a phosphoramidite monomer used in nucleic acid synthesis, such as oligonucleotides.
Cat. No.: HY-170351
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NH2-PEG2-OMs is the linker, that could be used for synthesis of PROTAC degrader DDC-01-163 (HY-139997) .
Cat. No.: HY-170350
CAS No.: 2140807-37-8
Research Areas:
Pomalidomide-PEG2-Oms (CRBN ligand Pomalidomide (HY-10984)) is an E3 Ligase Ligand-Linker Conjugate for EGFR PROTAC DDC-01-163 (HY-139997) .
Cat. No.: HY-W393396
CAS No.: 84472-90-2
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3'-NH2-ddC is a monomeric raw material that can be used for nucleic acid synthesis.
Cat. No.: HY-P701909
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ddC; Aromatic-L-amino-acid decarboxylase; AADC; DOPA decarboxylase; ddC
Cat. No.: HY-P701910
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ddC; Aromatic-L-amino-acid decarboxylase; AADC; DOPA decarboxylase; ddC
Cat. No.: HY-P704655
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ddC; Aromatic-L-amino-acid decarboxylase; AADC; DOPA decarboxylase; ddC
Species:
Source:
Cat. No.: HY-RS16935
Target:
Research Areas:
Ddc Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ddc gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23378
Target:
Research Areas:
Ddc Rat Pre-designed siRNA Set A contains three designed siRNAs for Ddc gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
