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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
ALK6
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "ALK6" in MCE Product Catalog:
806
806 Publications Verification
Synonyms: BML-275
Target:
Research Areas:
Dorsomorphin (BML-275) is a selective and ATP-competitive AMPK inhibitor (Ki=109 nM in the absence of AMP). Dorsomorphin (BML-275) selectively inhibits BMP type I receptors ALK2, ALK3, and ALK6. Dorsomorphin can reverse autophagy activation and anti-inflammatory effect of Urolithin A (HY-100599) .
806
806 Publications Verification
Synonyms: Compound C dihydrochloride; BML-275 dihydrochloride
Target:
Research Areas:
Dorsomorphin (Compound C) dihydrochloride is a potent, selective and ATP-competitive AMPK inhibitor, with a Ki of 109 nM. Dorsomorphin dihydrochloride inhibits BMP pathway by targeting the type I receptors ALK2, ALK3, and ALK6. Dorsomorphin dihydrochloride can reverse autophagy activation and anti-inflammatory effect of Urolithin A (HY-100599).
4
4 Cited Publications
Target:
Research Areas:
K02288 is a potent bone morphogenetic protein (BMP) type I receptor inhibitor with IC50s of 1.8, 1.1, 6.4 nM for ALK1, ALK2 and ALK6, respectively. K02288 shows slightly weaker inhibition against ALK3 and ALK6 with IC50s of of 5-34 nM.
Cat. No.: HY-117887
CAS No.: 2141955-96-4
Synonyms: BLU-782; IPN-60130; ALK2-IN-1
Target:
Research Areas:
Fidrisertib (BLU-782) is the orally active inhibitor for activin receptor-like kinase 2 (ALK2) that inhibits ALK2 R206H, ALK2, ALK1, ALK6, ALK3, ALK4, TGFβR2 and ALK5 with IC50s of 0.2, 0.6, 3, 24, 45, 65, 67 and 155 nM, respectively .
Cat. No.: HY-12273R
CAS No.: 1206711-16-1
Research Areas:
DMH-1 (Standard) is the analytical standard of DMH-1. DMH-1 is a potent and selective BMP inhibitor with IC50s of 27/107.9/<5/47.6 nM for ALK1/ALK2/ALK3/ALK6, respectively.
Cat. No.: HY-12273G
CAS No.: 1206711-16-1
Cat. No.: HY-P11354
Research Areas:
Cat. No.: HY-P11354A
Research Areas:
Cat. No.: HY-13418R
CAS No.: 1219168-18-9
Synonyms: Compound C dihydrochloride (Standard); BML-275 dihydrochloride (Standard)
Research Areas:
Dorsomorphin (dihydrochloride) (Standard) is the analytical standard of Dorsomorphin (dihydrochloride). This product is intended for research and analytical applications. Dorsomorphin (Compound C) dihydrochloride is a potent, selective and ATP-competitive AMPK inhibitor, with a Ki of 109 nM. Dorsomorphin dihydrochloride inhibits BMP pathway by targeting the type I receptors ALK2, ALK3, and ALK6. Dorsomorphin dihydrochloride can reverse autophagy activation and anti-inflammatory effect of Urolithin A (HY-100599).
Cat. No.: HY-12278G
CAS No.: 1431985-92-0
Cat. No.: HY-RS01549
Target:
Research Areas:
BMPR1B Human Pre-designed siRNA Set A contains three designed siRNAs for BMPR1B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS01550
Target:
Research Areas:
Bmpr1b Mouse Pre-designed siRNA Set A contains three designed siRNAs for Bmpr1b gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P76174
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Bone morphogenetic protein receptor type-1B; BMPR-1B; CDw293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
