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Results for "

AMCase

" in MedChemExpress (MCE) Product Catalog:

8

Inhibitors & Agonists

1

Fluorescent Dye

1

Peptides

2

Recombinant Proteins

2

Antibodies

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-D0026

    7-Amino-4-methyl-3-coumarinacetic acid N-succinimidyl ester

    Fluorescent Dye Others
    AMCA,SE (7-Amino-4-methyl-3-coumarinacetic acid N-succinimidyl ester) is a bright blue fluorescent dye. AMCA,SE reacts with amino groups and is excited by ultraviolet light. AMCA,SE can be used for amine reactive labeling (Ex/Em = 354/440 nm) .
    AMCA,SE
  • HY-P2797A

    AMCase, Streptomyces griseus

    Biochemical Assay Reagents Others
    Chitinase, Streptomyces griseus is a chitinase from Streptomyces griseus. Chitinase is a chitin-targeting enzyme with chitin hydrolysis activity. Chitinase inhibits chitin-induced innate type 2 inflammation in the lung. Chitinase augments chitin-free, allergen-induced Th2 inflammation. Chitinase mediates effector functions of IL-13 .
    Chitinase, Streptomyces griseus
  • HY-P2797

    AMCase, Serratia marcescens

    Biochemical Assay Reagents Metabolic Disease Inflammation/Immunology
    Chitinase, Serratia marcescens is a chitinase from Serratia marcescens. Chitinase is a chitin-targeting enzyme with chitin hydrolysis activity. Chitinase inhibits chitin-induced innate type 2 inflammation in the lung. Chitinase augments chitin-free, allergen-induced Th2 inflammation. Chitinase mediates effector functions of IL-13 .
    Chitinase, Serratia marcescens
  • HY-120107

    Parasite Inflammation/Immunology
    OAT-177 is a potent dual inhibitor targeting acidic mammalian chitinase (AMCase) and chitotriosidase (CHIT1) with an IC50=14.2 nM for human AMCase and IC50=232 nM for human CHIT1. OAT-177 is promising for research of chronic inflammatory and fibrotic-related lung diseases such as asthma and idiopathic pulmonary fibrosis .
    OAT-177
  • HY-RS02628

    Small Interfering RNA (siRNA) Others

    CHIA Human Pre-designed siRNA Set A contains three designed siRNAs for CHIA gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    CHIA Human Pre-designed siRNA Set A
    CHIA Human Pre-designed siRNA Set A
  • HY-115661

    Bacterial Infection
    Bisdionin C is a potent GH18 chitinases inhibitor, with an IC50 of 0.2 μM for A. fumigatus ChiB1 (AfChiB1). Bisdionin C inhibits HCHT (human macrophage chitotriosidase) and acidic mammalian chitinase (AMCase) with IC50s of 8.3 and 3.4 μM, respectively .
    Bisdionin C
  • HY-125279

    Parasite Inflammation/Immunology
    OAT-2068 is a selective, high activity and orally active inhibitor of mouse chitotriosidase (mCHIT1) (IC50=29 nM) and displays 143-fold selectivity over m AMCase (IC50=4170 nM). OAT-2068 displays a good pharmacokinetic profile and is an ideal tool to study the role of CHIT1 in biological systems, including animal models of human diseases .
    OAT-2068
  • HY-P10881

    Peptide-Drug Conjugates (PDCs) Metabolic Disease
    Ganipatide is a 1-31-Glucose-dependent insulinotropic polypeptide. Ganipatide is promising for research of diabetes .
    Ganipatide

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