14 Results for "

AMYR

" in MedChemExpress (MCE) Product Catalog:
Products (14)

14 Results for "AMYR" in MCE Product Catalog:

3
3 Cited Publications
Art. -Nr.: HY-P3462
CAS. Nr.: 1415456-99-3
Target:  

CGRP Receptor

Forschungsgebiete:  

Metabolic Disease

Cagrilintide is an investigational novel long-acting acylated amylin analogue, acts as nonselective amylin receptors (AMYR) and calcitonin G protein-coupled receptor (CTR) agonist. Cagrilintide induces significant weight loss and reduces food intake. Cagrilintide has the potential for the research of obesity .
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3
3 Cited Publications
Art. -Nr.: HY-P3462A
Target:  

CGRP Receptor

Forschungsgebiete:  

Metabolic Disease

Cagrilintide acetate is a non-selective AMYR/CTR agonist and long-acting acylated amylase analogue. Cagrilintide acetate causes a reduction in food intake and significant weight loss in a dose-dependent manner. Cagrilintide acetate can be used in obesity studies .
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Art. -Nr.: HY-P10798A
Synonyms: LY-3841136 sodium
Forschungsgebiete:  

Metabolic Disease

Eloralintide sodium is an Amylin Receptor agonist. Eloralintide sodium selectively activates AMY1R and AMY3R in cells expressing human or rat AMY1R, AMY3R or CTR. Eloralintide sodium activates AMYRs and CTR in rats, inducing a sustained decrease in plasma Ca 2+ levels. Eloralintide sodium reduces appetite and body weight in both lean and obese rats. Eloralintide sodium can be used for research related to obesity .
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Art. -Nr.: HY-179738
CAS. Nr.: 3097482-67-9
Forschungsgebiete:  

Metabolic Disease

CTR/AMYR modulator-1 is a calcitonin receptor/amylin receptor modulator. CTR/AMYR modulator-1 can be used for the research of metabolic disease .
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Art. -Nr.: HY-P11245
Target:  

Amylin Receptor

Forschungsgebiete:  

Metabolic Disease

NN1213, a long-acting human amylin peptide analog, is a selective Amylin receptor agonist with EC50 values of 0.177 and 0.262 nM for hAMY3R and rAMY3R, respectively. NN1213 significantly reduces food intake and fat mass. NN1213 can reduce body weightin diet-induced obese rats. NN1213 can be used for the research of obesity .
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Art. -Nr.: HY-CE01283
Synonyms: Coenzyme A-MYR
Forschungsgebiete:  

Metabolic Disease

CoA-MYR (Coenzyme A-MYR) is a coenzyme A derivative .
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Art. -Nr.: HY-185229
CAS. Nr.: 3108097-26-0
Forschungsgebiete:  

Metabolic Disease

CTR/AMYR agonist-1 is a CTR/AMYR agonist with EC50 values of 0.56-6.9 nM. CTR/AMYR agonist-1 can be used for the research of metabolic disease .
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Art. -Nr.: HY-185234
CAS. Nr.: 3068779-36-9
CTR/AMYR activator-1 (S configuration of compound 122) is a CTR/AMYR activator. CTR/AMYR activator-1 can be used in the research of bone diseases, metabolic diseases, cardiovascular diseases, and neurodegenerative diseases .
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Art. -Nr.: HY-185229A
CAS. Nr.: 3108097-24-8
Forschungsgebiete:  

Metabolic Disease

CTR/AMYR agonist-1 enantiomer is an enantiomer of CTR/AMYR agonist-1 (HY-185229). CTR/AMYR agonist-1 is a CTR/AMYR agonist with EC50 values of 0.56-6.9 nM. CTR/AMYR agonist-1 can be used for the research of metabolic disease .
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Art. -Nr.: HY-185234A
CAS. Nr.: 3068778-30-0
(R)-CTR/AMYR activator-1 (Compound 122) is a CTR/AMYR activator with EC50 values of 0.8 and 0.73 nM. (R)-CTR/AMYR activator-1 can used for the researches of bone diseases, metabolic diseases, cardiovascular diseases, and neurodegenerative diseases .
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Art. -Nr.: HY-185107
CAS. Nr.: 3108095-52-6
Forschungsgebiete:  

Metabolic Disease

CTR/AMYR modulator-2 (Example 107) is a receptor 3 for pancreatic amyloid peptide (bAMY3R) agonist, and its EC50 for stimulating cAMP production in cells is <500 nM. CTR/AMYR modulator-2 is also a receptor for calcitonin (bCTR) agonist, with its EC50 being <5000 nM. CTR/AMYR modulator-2 can be used for research on type 2 diabetes and obesity .
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Art. -Nr.: HY-186104
CAS. Nr.: 3097592-82-7
Forschungsgebiete:  

Metabolic Disease

AMYR/CTR agonist 1 (Compound 195) is a pancreatic amylin receptor and calcitonin receptor (AMYR/CTR) agonist with EC50 values for pancreatic amylin receptor and calcitonin receptor cAMP of 99.5 and 6.16 pM respectively. AMYR/CTR agonist 1 can be used in the research of diseases such as type 2 diabetes and obesity .
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Art. -Nr.: HY-185229B
CAS. Nr.: 3108096-13-2
Forschungsgebiete:  

Metabolic Disease

rel-CTR/AMYR agonist-1 (Example 169) is an agonist of amylin and/or calcitonin receptor .
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Art. -Nr.: HY-P11584
Forschungsgebiete:  

Metabolic Disease

KBP-066A is a long-acting dual amylin and calcitonin receptor agonist. KBP-066A can activate the CTR and AMY-R potently, with no off-target activity. KBP-066A reduces fasting blood glucose levels, fasting insulin levels, and body weight in diabetic rat models. KBP-066A can be used for the research of type 2 diabetes mellitus, obesity .
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