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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
ASBT
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "ASBT" in MCE Product Catalog:
13
Research Areas:
Linerixibat (GSK2330672) is a highly potent, nonabsorbable and orally active apical sodium-dependent bile acid transporter (ASBT) inhibitor with an IC50 of 42 nM human ASBT. Linerixibat can be used as lipid-lowering agent. Linerixibat has the potential for type 2 diabetes and Primary Biliary Cholangitis treatment .
4
Research Areas:
Odevixibat (A4250) is a selective and orally active ileal apical sodium-dependent bile acid transporter (ASBT) inhibitor. Odevixibat decreases cholestatic liver and bile duct injury in mice model. Odevixibat has the potential for the treatment of primary biliary cirrhosis .
Cat. No.: HY-101190
CAS No.: 1025216-57-2
Synonyms: SHP626; LUM002
Research Areas:
Volixibat (SHP626) is a highly selective, minimally absorbed, and competitive apical sodium-dependent bile acid transporter (ASBT) inhibitor. Volixibat has potential for treatment for non-alcoholic steatohepatitis (NASH) .
Cat. No.: HY-148795
CAS No.: 2460667-52-9
Research Areas:
Ritivixibat is an apical sodium-dependent bile acid transporter (ASBT/IBAT) inhibitor. Ritivixibat blocks ASBT/IBAT function, thereby reducing bile acid reabsorption, regulating bile acid homeostasis and alleviating liver injury. Ritivixibat protects cholangiocytes from damage caused by cytotoxic bile acids. Ritivixibat is applicable to research related to primary sclerosing cholangitis .
Research Areas:
SC-435 is an orally effective apical sodium codependent bile acid transporter (ASBT) inhibitor. SC-435 effectively removes neurotoxic bile acids and ammonia from the blood by inhibiting intestinal ASBT, thereby alleviating liver and brain damage caused by liver failure. SC-435 can alter hepatic cholesterol metabolism and lower plasma low-density lipoprotein-cholesterol concentrations .
Cat. No.: HY-168523
CAS No.: 259528-99-9
Research Areas:
S1647 is a ASBT and SOAT dual inhibitor. S1647 can be used in the study of intrahepatic cholestasis, cholestatic pruritus, and obstipation .
Cat. No.: HY-RS12987
Target:
Research Areas:
Slc10a2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Slc10a2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS12988
Target:
Research Areas:
Slc10a2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Slc10a2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS12986
Target:
Research Areas:
SLC10A2 Human Pre-designed siRNA Set A contains three designed siRNAs for SLC10A2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-109120R
CAS No.: 501692-44-0
Synonyms: A4250 (Standard)
Research Areas:
Odevixibat (Standard) is the analytical standard of Odevixibat. This product is intended for research and analytical applications. Odevixibat (A4250) is a selective and orally active ileal apical sodium-dependent bile acid transporter (ASBT) inhibitor. Odevixibat decreases cholestatic liver and bile duct injury in mice model. Odevixibat has the potential for the treatment of primary biliary cirrhosis .
Cat. No.: HY-109120S
Synonyms: A4250-d5
Cat. No.: HY-109120S1
Synonyms: A4250-13C6
Cat. No.: HY-P705614
Purity: Purity analysis by SDS-PAGE is not available for VLP proteins.
Synonyms: Apical sodium-dependent bile acid transporter; ASBT; Ileal sodium-dependent bile acid transporter; IBAT; ISBT; Na+; Sodium/taurocholate cotransporting polypeptide, ileal; Solute carrier family 10 member 2
Cat. No.: HY-101190A
Synonyms: (3R,4S,5S)-SHP626; (3R,4S,5S)-LUM002
Target:
Research Areas:
(3R,4S,5S)-Volixibat ((3R,4S,5S)-SHP626) is an isomer of Volixibat (HY-101190). Volixibat is a highly selective, minimally absorbed, and competitive apical sodium-dependent bile acid transporter (ASBT) inhibitor. (3R,4S,5S)-Volixibat may be used in research on non-alcoholic steatohepatitis (NASH) .
Target:
Research Areas:
Homocholic acid is a synthetic steroid analogue. Homocholic acid can be labeled with 75Se and is used for SeHCAT detection (a method for diagnosing bile acid malabsorption) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
